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Fat tissue, immune dysfunction and cellular senescence are closely related. Here we have some commentary from Reason at Fightaging! once of our new Patron sponsors about some recent research liking these factors together.

“Cellular senescence is one of the root causes of aging, and there are at present serious, well-funded efforts underway to produce rejuvenation therapies based on the selective destruction of senescent cells in old tissues. This progress is welcome, but it could have started a long time ago. It has taken many years of advocacy and the shoestring production of technology demonstrations to finally convince the broader community of scientists and funding institutions that the evidence has long merited serious investment in treatments to clear senescent cells”.

#sens #aging

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Bioprinting has been all over the news in the past several years with headline-worthy breakthroughs like printed human skin, synthetic bones, and even a fully functional mouse thyroid gland.

3D printing paved the way for bioprinting thanks to the printers’ unique ability to recreate human tissue structures; their software can be written to ‘stack’ cells in precise patterns as directed by a digital model, and they can produce tissue in just hours and make numerous identical samples.

Despite the progress in bioprinting, however, more complex human organs continue to elude scientists, and resting near the top of the ‘more complex’ list are the kidneys.

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More progress to help stroke victims.


Researchers at The University of Manchester have discovered that a potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage.

A reduction in blood flow to the brain caused by is a major cause of death and disability, and there are few effective treatments.

A team of scientists at The University of Manchester has now found that a potential new stroke drug not only works in rodents by limiting the death of existing brain cells but also by promoting the birth of new neurones (so-called neurogenesis).

Glasgow University has taken delivery of Scotland’s most powerful magnetic resonance imaging (MRI) scanner.

The £10m device was lifted into place at the new Imaging Centre of Excellence (ICE) at the city’s Queen Elizabeth University Hospital (QEUH).

A giant crane eased the 18-tonne scanner down an alleyway with inches to spare on each side, then through a hole in the wall of the new building.

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