Professor YongKeun Park of the Physics Department at the Korea Advanced Institute of Science and Technology and his research team have developed a powerful method for 3D imaging of live cells without staining.
The new microscopic tool is called the holotomography (HT)-1. It was announced to the global marketplace through a Korean start-up that Professor Park co-founded called TomoCube.
From the measurement of multiple 2D holograms of a cell, coupled with various angles of laser illuminations, the 3D refractive index (RI) distribution of the cell can be reconstructed. This 3D map provides structural and chemical information, such as dry mass and protein concentration.
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