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Grassroots funding of fundamental science and private enterprize will lead the way in rejuvenation biotechnology not the traditional funding sources from Government which are shrinking every year.


It is important to understand that innovation and progress is unlikely to come from the Government and the traditional grant system which is shrinking every year. Rejuvenation biotechnology will likely be funded with a mix of fundraising for fundamental breakthrough technologies followed by private enterprize taking discoveries to market. This is why supporting science is critcial as relying on the Government to innovate and drive progress is unlikely to yield results anytime soon.

“Today, researchers compete for government grants at increasingly shorter intervals and with diminishing chances of success: Less than 1 in 5 grant applications succeeds. This inhibits risk taking.

By contrast, private investment in medicine has kept pace with the aging population and is the principal engine for advancement. More than 80% of new drug approvals originate from work solely performed in private companies. Note that such drug approvals come on average 16 years after the beginning of clinical trials, which typically cost $2.5 billion from start to finish. Even if grant-subsidized academics wanted to create a new drug, economic reality prevents it.”

CRISPR can help us end many diseases and guide evolution and is probably one of the most powerful tools we have recently added to our toolkit.


Imagine you could edit a mouse’s genes to be resistant to Lyme Disease. The mouse would breed and evolution would take its course, leading to the extinction of the disease. That’s the vision for scientists developing CRISPR, technology that allows scientists to rewrite the code of life. William Brangham talks to Michael Specter who wrote about CRISPR for The New Yorker.

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What happens when you have Deep Learning begin to generate your designs? The commons misconception would be that a machine’s design would look ‘mechanical’ or ‘logical’. However, what we seem to be finding is that they look very organic, in fact they look organic or like an alien biology. Take a look at some of these fascinating designs.

The photo above design is described as follows:

“This is not only an exciting development for the construction sector, but many other industries as well. In the case of this particular piece, the height is approximately half that of one designed for traditional production methods, while the direct weight reduction per node is 75%. On a construction project that means we could be looking at an overall weight reduction of the total structure of more than 40%. But the really exciting part is that this technique can potentially be applied to any industry that uses complex, high quality, metal products.”

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One of the most powerful observing instruments on Earth, the Very Large Telescope, will join the search for potentially habitable planets around the Alpha Centauri star system.

The survey will take place in 2019 under the terms of an agreement signed by the European Southern Observatory, which operates the VLT in Chile, and by the Breakthrough Initiatives.

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It’s an exciting time to be an elderly mouse. Researchers believe that by removing senescent cells (cells with a persistent damage response), which naturally accumulate with age, senior rodents can regrow hair, run faster, and improve organ function. This strategy may bring us one step closer to the “fountain of youth,” but it’s important to be cautious and not hype, says researcher of aging Peter de Keizer of the Erasmus University Medical Center in the Netherlands. In an Opinion published December 29 in Trends in Molecule Medicine, he discusses the milestones the field still needs to hit before translation in humans is ready for discussion.

#aging #crowdfundthecure

https://www.sciencedaily.com/releases/2016/12/161229141835.htm

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121 people including me have already sent their gifts to CellAge project, what about you? wink


Hello everyone! There are some great news, today CellAge campaign successfully reached amazing $6 000! This makes 15% of the goal, and we are very grateful to 121 brave people who decided to support the development of a universal test system to target senescent cells!

If you have not yet supported the campaign with a donation, here is a reminder that the best New Year gift for scientists is funding to launch another longevity study! bigsmile

#crowdfundthecure for #aging