Tissue engineering makes further progress for repairing damaged joints.
Writing in The Lancet, Swiss doctors report that cartilage cells harvested from patients’ own noses have been used to successfully produce cartilage transplants for the treatment of the knees of 10 adults (aged 18–55 years) whose cartilage was damaged by injury. Two years after reconstruction, most recipients reported improvements in pain, knee function, and quality of life, as well as developing repair tissue that is similar in composition to native cartilage.
Despite this promising start, however, the effectiveness of the procedure needs to be rigorously assessed in larger randomised trials compared to conventional treatments and with longer follow up before any firm conclusions can be drawn about its use in routine clinical practice, say the authors.
Every year, around 2 million people across Europe and the USA are diagnosed with damage to articular cartilage because of injuries or accidents. Articular cartilage is the tissue on the end of a bone that cushions the surface of the joint and is vital for painless movement. Because the tissue doesn’t have its own blood supply, it has limited capacity to repair itself once damaged, leading to degenerative joint conditions like osteoarthritis. Traditional methods to prevent or delay onset of cartilage degeneration following traumatic events like microfracture surgery don’t create the healthy cartilage needed to endure the forces of everyday movement. Even novel medical advances using patients’ own articular cartilage cells (chondrocytes) have been unable to predictably restore cartilage structure and function in the long term. As the population ages and people live longer, there is an urgent and growing need to develop an effective therapy to repair cartilage damage.
Microcomputers are great for learning about code and hardware. The VoCore2 Mini is the smallest ever, packing full Linux functionality and wireless connectivity into a coin-sized device. New Atlas Deals has it for just $42.99.
This impressive little computer is capable of running programs in C, Java, Ruby, JavaScript, and many other languages. This means you can code the VoCore2 to expand its functionality, turning it into a VPN gateway, airplay music station, and much more.
You can also augment the VoCore2 with hardware components for further tinkering fun. Add a USB webcam to turn it into a home security camera, attach a microphone to issue voice commands to Siri or Echo, and so on. Your projects are limited only by your imagination.
Combination therapy to kick cancer to the curb!
Harnessing the body’s own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.
In the new study, the researchers used a combination of four different therapies to activate both of the immune system’s two branches, producing a coordinated attack that led to the complete disappearance of large, aggressive tumors in mice.
“We have shown that with the right combination of signals, the endogenous immune system can routinely overcome large immunosuppressive tumors, which was an unanswered question,” says Darrell Irvine, a professor of biological engineering and of materials science and engineering, and a member of MIT’s Koch Institute for Integrative Cancer Research.
BELGRADE – NASA’s ground-breaking voyager 2 probe is more than 3 decades into its epic journey towards deep space. On April 22nd, 2010 just as the craft prepares to cross the boundary to enter into interstellar space, it malfunctions, physics-astronomy.com reported.
As NASA’s planetary scientist, Kevin Baines said:
“Just about 10 billion miles away from the Earth and all of the sudden it starts sending data in the language we don’t understand. It can be called as an alien language”
Gene therapy in a box could reduce costs and save lives.
Gene therapy — the process of genetically altering cells to treat disease — is a highly promising process being studied as a way to cure devastating conditions like genetic disorders, HIV, and even cancer.
But despite the great need for medical advances in these areas, gene therapy can only be performed at a handful of high-tech clinics around the world and require highly trained staff, meaning that it may never be accessible to the millions of people whose lives it could save.
Enter “gene therapy in a box,” a table-top device developed at the Fred Hutchinson Cancer Research center in Seattle, which could provide gene therapy treatments without the expensive and rare medical infrastructure currently needed. My hope is that this technology… could open the door to saving millions of lives.
Gene therapy — the process of genetically altering cells to treat disease — is a highly promising process being studied as a way to cure devastating conditions like genetic disorders, HIV, and even cancer.