Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 10

Get the latest international news and world events from around the world.

Log in for authorized contributors

From Generative To Agentic: The New Era Of AI Autonomy In 2026

#artificialintelligence

Agentic AI is a form of artificial intelligence that does more than just generate; it will act, reason somewhat, collaborate, and execute on its own. Agentic AI transforms its role from a limited tool to that of a collaborative coworker.

This shift affects various sectors, including cybersecurity, national defense, healthcare, key infrastructure, finance, supply chains, and corporate automation. Additionally, it accelerates the integration of robotics, neuromorphic systems, sensor-driven edge computing, and artificial intelligence.

Systems with the ability to plan and pursue goals characterize Agentic AI. IIt combines APIs and tools, engages with dynamic environments, makes decisions, uses reasoning, and continues to learn and adapt.

ENeuro Blog

These images have been selected to showcase the art that neuroscience research can create.

As described by the authors: The cacophony voltage-gated calcium channel serves as the primary conduit for the calcium that triggers neurotransmitter release at countless synapses across the fruit fly (Drosophila) nervous system. To support this role at different synapse types, alternate splicing confers different biophysical properties upon cacophony. However, conventional techniques that might discriminate splice isoforms, such as antibodies, toxins, and pharmacological agents, are poorly suited for identifying splice isoforms across multiple neurons in a living nervous system.

This image demonstrates the transgenic expression of a bichromatic fluorescent exon reporter in most neurons of the fly brain. Green fluorescent protein (GFP) fluorescence was particularly bright relative to red fluorescent protein (TagRFP) in the α, β, and γ lobes of the mushroom body (MB), indicating a bias towards the inclusion of exon 11 at the expense of exon 10. Differences were also evident between neurons of the optic lobes.

Large language models and research progress: Q&A with an aerospace engineer

The rapid expansion of large language models’ (LLMs) capabilities—including web search, code execution, data analysis and even hypothesis generation and experimental design—is outpacing critical reflection of how the technology fits into academic research.

This is the argument that Ricardo Vinuesa, an associate professor of aerospace engineering at U-M, and his co-authors made in the journal The Innovation.

Though they acknowledge that LLMs are helpful for generating a speedy first draft, adopting LLMs into every stage of the research process without proper guardrails creates risk of misconduct, such as data fabrication or biased experimental design.

Ultrasound-responsive nanoparticles: Modulating the tumor microenvironment to advance cancer immunotherapy

Ultrasound-responsive nanoparticles (URNs) enable spatiotemporal activation of immunomodulators that can remodel the tumor microenvironment and strengthen immune responses. This review summarizes how URNs enhance immune checkpoint blockade, vaccines, T cell therapies, cytokine delivery, and innate immune modulators, while synergizing with strategies such as oxygenation, extracellular matrix depletion, metabolic reprogramming, and phototherapy. By offering precise control and reduced systemic toxicity, URNs represent a promising platform for the rational design of next-generation cancer immunotherapies.

The “StemDif Sensor Test”: A Straightforward, Non-Invasive Assay to Characterize the Secreted Stemness and/or Differentiation Activities of Tumor-Derived Cancer Cell Lines

Cancer stem cells are a subpopulation of tumor cells characterized by their ability to self-renew, induce tumors upon engraftment in animals and exhibit strong resistance to chemotherapy and radiotherapy. These cells exhibit numerous characteristics in common with embryonic stem cells, expressing some of their markers, typically absent in non-pathological adult differentiated cells. The aim of this study was to investigate the potential of conditioned media from cancer stem cells to modulate the fate of Leukemia Inhibitory Factor (LIF)-dependent murine embryonic stem cells (mESCs) as a way to obtain a direct readout of the secretome of cancer cells. A functional assay, “the StemDif sensor test”, was developed with two types of cancer stem cells derived from grade IV glioblastoma (adult and pediatric) or from gastric adenocarcinoma.

Carotenoids Are Associated With A Younger Biological Age

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Discount Links/Affiliates:
Blood testing (where I get the majority of my labs): https://www.ultalabtests.com/partners/michaellustgarten.

At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten.
Use Code: CONQUERAGING At Checkout.

Clearly Filtered Water Filter: https://get.aspr.app/SHoPY

Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ6…M0&irgwc=1
Use Code: CONQUERAGING

NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/

Continue reading “Carotenoids Are Associated With A Younger Biological Age” | >

Google’s plan for space-based computing

The sun produces more power than 100 trillion times humanity’s entire electricity generation. In orbit, solar panels can be eight times more productive than their Earth-bound counterparts, generating energy almost continuously without the need for heavy battery storage. These facts have led a team of Google researchers to ask what if the best place to scale artificial intelligence isn’t on Earth at all, but in space?

Project Suncatcher, Google’s latest space mission, envisions constellations of solar-powered satellites equipped with processors and connected by laser-based optical links. The concept tackles one of AI’s most pressing challenges, the enormous energy demands of large-scale machine learning systems, by tapping directly into the solar system’s ultimate power source. A new research paper published by Google describes their progress toward addressing the technical challenges.

The proposed system would operate in a sun-synchronous low Earth orbit, where satellites remain in almost constant sunlight. This orbital choice maximizes solar energy collection while minimizing battery requirements. However, making space-based AI infrastructure viable requires solving several formidable engineering challenges.

Turning the gut microbiome into a longevity factory

A team of researchers has found a way to turn the bacteria living in the digestive tracts of animals into factories that can produce compounds that promote longevity in their hosts—showing a potential new drug development strategy.

Janelia Senior Group Leader Meng Wang and her team study longevity and were interested in seeing how they could transfer their research findings about longevity-promoting compounds into practical applications.

One idea they had was to induce the body’s gut microbiota—a collection of bacteria in the gut that produces many different compounds—to produce metabolites that benefit their host animals. They started with one compound, colanic acid, which is generated by bacteria in the gut and had previously been found to promote longevity in roundworms and fruit flies.

/* */