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By David Ewalt

REUTERS TOP 25

N” Silicon Valley’s hoodie-wearing tech entrepreneurs are the poster kids of innovation. But the innovators who are really changing the world are more likely to wear labcoats and hold government-related jobs in Grenoble, Munich or Tokyo. That’s the conclusion of Reuters’ Top 25 Global Innovators – Government, a list that identifies and ranks the publicly funded institutions doing the most to advance science and technology.

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SAN FRANCISCO A company now owned by Uber last year quietly bought a small firm specializing in sensor technology used in autonomous vehicles, giving the ride services company a patent in the technology and possibly a defense against a trade secrets theft lawsuit filed against it by rival Alphabet Inc.

The chief executive of little-known Tyto Lidar LLC said in a May 2016 post on LinkedIn that the company had been sold, at the same time as he and three other executives joined Otto, according to their profiles on the online business network. Official U.S. patent data shows Otto acquired Tyto technology at the same time.

Otto, a self-driving truck startup founded by former Alphabet employees, was bought by Uber in August.

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A core set of genes involved in the responses of honey bees to multiple diseases caused by viruses and parasites has been identified by an international team of researchers. The findings provide a better-defined starting point for future studies of honey-bee health, and may help scientists and beekeepers breed honey bees that are more resilient to stress.

“In the past decade, honey-bee populations have experienced severe and persistent losses across the Northern Hemisphere, mainly due to the effects of , such as fungi and viruses,” said Vincent Doublet, postdoctoral research fellow, University of Exeter. “The genes that we identified offer new possibilities for the generation of honey-bee stocks that are resistant to these pathogens.”

According to the researchers, recent advances in DNA sequencing have prompted numerous investigations of the genes involved in honey-bee responses to pathogens. Yet, until now, this vast quantity of data has been too cumbersome and idiosyncratic to reveal overarching patterns in honey-bee immunity.

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Research from McMaster University has found that bacteria in the gut impacts both intestinal and behavioural symptoms in patients suffering from irritable bowel syndrome (IBS), a finding which could lead to new microbiota-directed treatments.

The new study, published today in Science Translational Medicine, was led by researchers from the Farncombe Family Digestive Health Research Institute at McMaster, Drs. Premysl Bercik and Stephen Collins, in collaboration with researchers from the University of Waterloo.

IBS is the most common gastrointestinal disorder in the world. It affects the large intestine and patients suffer from abdominal pain and altered bowel habits like diarrhea and constipation, which are often accompanied by chronic anxiety or depression. Current treatments aimed at improving symptoms have limited efficacy because the underlying causes are unknown.

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