Lifeboat Foundation: Safeguarding Humanity
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Blog – Page 10,978

If there was a poster child of aging diseases, it would be Alzheimer’s disease. The brains of people suffering from Alzheimer’s disease have deposits of amyloids resulting from the loss of proteostasis. Alzheimer’s disease is accompanied by the presence of amyloid beta protein and tau protein as well as large numbers of activated pro-inflammatory immune cells.

The debate about which is primary has raged for many years in the research world, and it is still not clear how these three elements combine to cause disease progression. A new study has attempted to untangle the mystery and suggests the order is beta amyloid, inflammation, then tau, and this study identifies new targets for therapies[1].

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A massive asteroid estimated to be 2.7 miles wide is set to make a ‘relatively close encounter’ with Earth on 1 September.

Dubbed ‘Florence,’ the huge space rock will pass just 4.4 million miles from our planet on Friday – or, about 18 times the distance between Earth and the moon.

According to NASA, this is the closest an asteroid of this size has come since they first began tracking near-Earth objects, giving scientists an unprecedented opportunity to study it up close through ground-based radar observations.

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Fantastic momentum so far on the MouseAge campaign, which raised over 10% of its goal on the first day! To learn more about how we are speeding up research and helping reduce animal suffering vist the campaign page:

https://www.lifespan.io/campaigns/mouseage-photographic-aging-clock-in-mice

A big thanks to Elena Milova, Thomas Klauset Aurdal, Jim Mellon (Juvenescence), James Joyce, Emanuele Ascani, Louie Helm, Martin Kleman, William DeVore, John D Gauchat, Peter Svensson, Poly Mamoshina, Felix Weimer, Reason (Fight Aging), Gennady Stolyarov (US Transhumanist Party). Alexey Strygin, Aleksandr Popov, Lars Christensen, Matthew Clarke and our Anonymous donors!

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Remember the 1980s movie Brewster’s Millions, in which a minor league baseball pitcher (played by Richard Pryor) must spend $30 million in 30 days to inherit $300 million? Pryor goes on an epic spending spree for a bigger payoff down the road.

One of the world’s biggest public companies is making that film look like a weekend in the Hamptons. Japan’s SoftBank Group, led by its indefatigable CEO Masayoshi Son, is shooting to invest $100 billion over the next five years toward what the company calls the information revolution.

The newly-created SoftBank Vision Fund, with a handful of key investors, appears ready to almost single-handedly hack the technology revolution. Announced only last year, the fund had its first major close in May with $93 billion in committed capital. The rest of the money is expected to be raised this year.

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