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In February 2023, Frontiers in Science published an article titled “Organoid Intelligence (OI): The New Frontier in Biocomputing and Intelligence-in-a-Dish.” Since its publication, this research has sparked significant scientific interest and gained coverage in Forbes, Financial Times, Wall Street Journal, BBC, CNN and many others.

So, what is organoid intelligence and why has this article gathered such attention?

The article showcases a forward-thinking and captivating concept of how brain organoids – artificially grown human brain tissue – could be used to study human brain cognitive function, with potential assistance from artificial intelligence and biocomputing. This multidisciplinary, emerging field holds great promise for advancing our understanding of the brain and accelerating progress in neuroscience research.

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Domain walls, long a divisive topic in physics, may be ideal explanations for some bizarre cosmic quirks.

By Anil Ananthaswamy

“As long as they live for long enough, they will always become large cosmological beasts,” says Ricardo Ferreira, a cosmologist at the University of Coimbra in Portugal. He’s not talking about actual beasts but rather about hypothetical humongous sheets of spacetime that could divide one region of the universe from another. Such so-called domain walls are the natural outcome of theories that try to solve some of the deepest mysteries in physics, such as the origins of gravity. As Ferreira says, however, had they formed after the big bang, by today they’d be the dominant source of energy in our universe, and there’s no evidence that’s the case. So any theory invoking their existence has been considered suspect—until now, perhaps.

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In an effort to make them useless to poachers, researchers are implanting radioactive isotopes into the horns of rhinos in South Africa.

The unusual material would “render the horn useless… essentially poisonous for human consumption,” James Larkin, professor and dean of science at the University of the Witwatersrand in Johannesburg, told Agence France-Presse.

The isotopes would also be “strong enough to set off detectors that are installed globally,” Larkin added, referring to hardware that was originally installed to “prevent nuclear terrorism.”

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Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles — structures that transport waste or food within cells.

In a recent ACS Nano paper (“The Secret Ballet Inside Multivesicular Bodies”), Luis Mayorga and Diego Masone shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.

A representation of multilayer lipid vesicles inspired by “Color Study: Squares with Concentric Circles,” by the artist Wassily Kandinsky. (Image: ACS Nano 2024, DOI: 10.1021/acsnano.4c01590)

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“Surfaces were invented by the devil” — this quote is attributed to the theoretical physicist Wolfgang Pauli, who taught at ETH Zurich for many years and in 1945 received the Nobel Prize in physics for his contributions to quantum mechanics. Researchers do, indeed, struggle with surfaces. On the one hand they are extremely important both in animate and inanimate nature, but on the other hand it can be devilishly difficult to study them with conventional methods.

An interdisciplinary team of materials scientists and electrical engineers led by Lukas Novotny, Professor of Photonics at ETH Zurich, together with colleagues at Humboldt-Universität zu Berlin has now developed a method that will make the characterization of surfaces considerably easier in the future.

They recently published the results of their research, which is based on an extremely thin gold membrane, in the scientific journal Nature Communications (“Bulk-suppressed and surface-sensitive Raman scattering by transferable plasmonic membranes with irregular slot-shaped nanopores”).

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Neurogenetic disorders, such as neurofibromatosis type 1 (NF1), are diseases caused by a defect in one or more genes, which can sometimes result in cognitive and motor impairments. Better understanding the neural underpinning of these disorders and how they affect motor and cognitive abilities could contribute to the development of new treatment strategies.

Researchers at Stanford University and Washington University School of Medicine recently performed a study on mice aimed at investigating the impact of Nf1 gene mutations, which cause the NF1 neurogenetic disorder, on oligodendroglial plasticity, an adaptive brain process known to contribute to cognitive and motor functions.

Their findings, published in Nature Neuroscience, provide strong evidence that Nf1 mutations delay the development of oligodendroglia, a type of glial cells that support the functioning of the central nervous system, causing disruptions in motor learning.

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This fleshy, pink smiling face is made from living human skin cells, and was created as part of an experiment to let robots show emotion.

How would such a living tissue surface, whatever its advantages and disadvantages, attach to the mechanical foundation of a robot’s limb or “face”?

In humans and…

A team of scientists unveiled a robot face covered with a delicate layer of living skin that heals itself and crinkles into a smile in hopes of developing more human-like cyborgs.

Continue reading “Robot face with lab-grown living skin created by scientists hoping to make more human-like cyborgs” | >