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MIT Researchers Can Shrink Objects to Nanoscale

MIT researchers invented a method of shrinking objects to the nanoscale.

The team can generate structures one-thousandth the volume of the original using a variety of materials, including metals, quantum dots, and DNA.

Existing techniques—like etching patterns onto a surface with light—work for 2D nanostructures, but not 3D. And while it’s possible to make 3D nanostructures, the process is slow, challenging, and restrictive.

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Progress in super-resolution microscopy

Going deeper and deeper into cells with the microscope; imaging the nucleus and other structures more and more accurately; getting the most detailed views of cellular multi-protein complexes: All of these are goals pursued by the microscopy expert Markus Sauer at the Biocenter of Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany. Together with researchers from Geneva and Lausanne in Switzerland, he has now shown that a hitherto uncertain method of super-resolution microscopy is reliable.

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