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SENS Research Foundation co-founder Aubrey de Grey believes in a world in which we no longer age. At a London event, he explained that he believes the first person who will live to be 1,000 has already been born, and we’ll solve this “aging problem” within 20 years.

Aging has plagued biological organisms since life first began on planet Earth and it’s an accepted and universally understood part of life. Sure, things like climate change pose significant threats to society, but aging will almost certainly still exist even if we ever manage to stop damaging our environment.

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Dr. Aubrey de Grey Summarizes Rejuvenation Research at the MIT Technology Review. To learn more about the work of Dr. Aubrey de Grey and the SENS Foundation visit http://www.sens.org/


Since the dawn of medicine, aging has been doctors’ foremost challenge. Three unsuccessful approaches to conquering it have failed: treating components of age-related ill health as curable diseases, extrapolating from differences between species in the rate of aging, and emulating the life extension that famine elicits in short-lived species. SENS Research Foundation is spearheading the fourth age of anti-aging research: the repair of age-related damage, that is, rejuvenation biotechnology.

The Strategies for Engineered Negligible Senescence (SENS) approach was first proposed in 2002. “Senescence,” here, refers to the actuarial phenomenon—the trend that individuals within a population suffer from an increasing morbidity and mortality rate in (typically exponential) relation to their chronological age. “Negligible” is used in a statistical sense: we consider a level of senescence negligible if no age-related contribution to mortality is statistically demonstrable within a population, given the “background noise” of age-independent mortality (such as unfortunate encounters with motor vehicles). Finally, by “Engineered,” we indicate that this state is achieved by the deliberate application of biomedical therapies, and is not the normal situation. The goal of SENSE is thus unambiguously defined; we seek methods to convert a population experiencing a non-negligible level of senescence into one experiencing a negligible level.

To see how the goal of negligible senescence could be “engineered,” it is useful to consider a situation in which human ingenuity and perseverance has already achieved an analogous result. Motor vehicles experience a process of wear-and-tear essentially similar to organismal aging; the paint flakes, windowpanes chip, rust infiltrates the pipework, and so forth. Nonetheless, as vintage car owners will attest, it is entirely possible to keep one functional for an essentially indefinite period. Critically, this is achieved not by preventing the wear but by repairing the damage that does occur at a rate sufficient to ensure that the function of the machine is never irretrievably compromised.

Summary: Cryonics has long been a non-starter due to technical limitations. A week-old radical proposal by a Russian cryonics firm to freeze people before death, combined with technological advances in Cryopreservation: Also called cryobanking. The process of cooling and storing cells, tissues, or organs at very low or freezing temperatures to save them for future use. Used in cryonics and the storage of reproductive cells in fertility treatments. [Source – NCI].” class=” glossaryLink “cryopreservation are shaking up the cryonics industry. When will cryonics be ready for prime time? [Author: Brady Hartman. This article first appeared on LongevityFacts.com. Follow us on Reddit | Google+ | Facebook. ]

Google’s most famous technologist, Ray Kurzweil, has signed up for cryonics, saying:

“My primary strategy for living through the 21st century and beyond is not to die”

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The soft artificial heart was created from silicone using a 3D-printing, lost-wax casting technique; it weighs 390 grams and has a volume of 679 cm3. “It is a silicone monoblock with complex inner structure,” explains Cohrs. This artificial heart has a right and a left ventricle, just like a real human heart, though they are not separated by a septum but by an additional chamber. This chamber is in- and deflated by pressurized air and is required to pump fluid from the blood chambers, thus replacing the muscle contraction of the human heart.

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