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Apr 1, 2024

Memories are made by breaking DNA — and fixing it

Posted by in categories: biotech/medical, business, neuroscience

When a long-term memory forms, some brain cells experience a rush of electrical activity so strong that it snaps their DNA. Then, an inflammatory response kicks in, repairing this damage and helping to cement the memory, a study in mice shows. The findings, published on 27 March in Nature1, are “extremely exciting”, says Li-Huei Tsai, a neurobiologist at the Massachusetts Institute of Technology in Cambridge who was not involved in the work. They contribute to the picture that forming memories is a “risky business”, she says. Normally, breaks in both strands of the double helix DNA molecule are associated with diseases including cancer. But in this case, the DNA damage-and-repair cycle offers one explanation for how memories might form and last.

It also suggests a tantalizing possibility: this cycle might be faulty in people with neurodegenerative diseases such as Alzheimer’s, causing a build-up of errors in a neuron’s DNA, says study co-author Jelena Radulovic, a neuroscientist at the Albert Einstein College of Medicine in New York City.

Apr 1, 2024

Unlocking the Secrets of Life With RNA’s Ancient Code

Posted by in categories: biotech/medical, genetics, robotics/AI

Salk scientists unveil RNA capabilities that enable Darwinian evolution at a molecular scale, and bring researchers closer to producing autonomous RNA life in the laboratory.

Charles Darwin described evolution as “descent with modification.” Genetic information in the form of DNA sequences is copied and passed down from one generation to the next. But this process must also be somewhat flexible, allowing slight variations of genes to arise over time and introduce new traits into the population.

Continue reading “Unlocking the Secrets of Life With RNA’s Ancient Code” »

Apr 1, 2024

Decoding Earth’s Cosmic Shields in Groundbreaking Study

Posted by in categories: particle physics, space

New insights into near-Earth space’s hazardous environment could revolutionize space weather prediction, driven by collaborative international research.

A challenge to space scientists to better understand our hazardous near-Earth space environment has been set in a new study led by the University of Birmingham.

The research represents the first step towards new theories and methods that will help scientists predict and analyze the behavior of particles in space. It has implications for theoretical research, as well as for practical applications such as space weather forecasting.

Apr 1, 2024

Quantum Computing Recharged With Electromagnetic Ion Trap Innovation

Posted by in categories: computing, quantum physics

Researchers at ETH have managed to trap ions using static electric and magnetic fields and to perform quantum operations on them. In the future, such traps could be used to realize quantum computers with far more quantum bits than have been possible up to now.

Apr 1, 2024

When Trees Fall, Mercury Rises: Unveiling a Hidden Environmental Threat

Posted by in category: space

Scientists quantify a previously overlooked driver of human-related mercury emissions.

About 10 percent of human-made mercury emissions into the atmosphere each year are the result of global deforestation, according to a new MIT study.

The world’s vegetation, from the Amazon rainforest to the savannahs of sub-Saharan Africa, acts as a sink that removes the toxic pollutant from the air. However, if the current rate of deforestation remains unchanged or accelerates, the researchers estimate that net mercury emissions will keep increasing.

Apr 1, 2024

Electro-Fenton Magic Makes Methane the New Eco Fuel Hero

Posted by in categories: chemistry, energy, physics

A team from the Dalian Institute of Chemical Physics made a breakthrough in converting methane to formic acid using oxygen at room temperature through a high-pressure electro-Fenton process, achieving significantly higher efficiency and productivity than traditional methods.

Direct conversion of methane (CH4) and oxygen (O2) to value-added chemicals is important for natural gas industries. However, challenges remain due to the difficulty of O2 activation in forming active oxygen species for CH4 activation under mild conditions.

Recently, a research group led by Prof. Dehui Deng, Assoc. Prof. Xiaoju Cui and Liang Yu from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) realized the electrochemical conversion of CH4 by O2 to formic acid (HCOOH) at room temperature. This study was published in the Journal of the American Chemical Society.

Apr 1, 2024

Defying Expectations: NASA’s Chandra Uncovers a Quasar’s Surprising Galactic Impact

Posted by in category: cosmology

Research reveals the quasar H1821+643, despite its intense activity, has a minimal effect on its host galaxy, overturning expectations about the role of quasars. Astronomers have found a rapidly growing supermassive black hole (quasar) not achieving what they expect from it.

Apr 1, 2024

Photonics Breakthrough: Tiny Chip Generates High-Quality Microwave Signals

Posted by in categories: robotics/AI, transportation

Researchers create a compact, all-optical device with the lowest microwave noise ever achieved for an integrated chip.

In a new Nature study, Columbia Engineering researchers have built a photonic chip that can produce high-quality, ultra-low-noise microwave signals using only a single laser. The compact device — a chip so small, it could fit on a sharp pencil point — results in the lowest microwave noise ever observed in an integrated photonics platform. The achievement provides a promising pathway towards small-footprint ultra-low-noise microwave generation for applications such as high-speed communication, atomic clocks, and autonomous vehicles.

Apr 1, 2024

Pushing the Limit of the Periodic Table — “Superheavy” Elements Challenge Theory

Posted by in category: chemistry

Scientists from leading global institutions are advancing our understanding of the periodic table by exploring superheavy elements and the theoretical “island of stability.” Their research, highlighted in prestigious scientific publications, seeks to uncover the properties of elements with over 103 protons and to predict their behavior through theoretical models. This work promises to expand the boundaries of the periodic table and impact a range of scientific fields.

Scientists from Massey University in New Zealand, the University of Mainz in Germany, Sorbonne University in France, and the Facility for Rare Isotope Beams (FRIB) discuss the limit of the periodic table and revising the concept of the “island of stability” with recent advances in superheavy element research. Their work is the cover feature of the February 2024 Nature Review Physics.

In addition to the Nature Reviews Physics feature, Physics Reports published a review on the atomic electronic structure theory for superheavy elements.

Apr 1, 2024

Ghostly Presences: Scientists Shed Light on the Unseen Forces Shaping Our Social Reality

Posted by in category: biotech/medical

If you had to estimate the number of people in a room, without counting them one-by-one, by nature you would overcount them. That’s because, simply put from a Darwinian perspective of how we have evolved, it’s better to overcount potentially harmful agents and predators than to underestimate them.

This overcounting social behaviour is shown to be true in humans as well as animals. It’s certainly better to detect too many tigers (even if absent) during a jungle excursion than to miss a hungry one!

Now, EPFL neuroscientists show that if you experience hallucinations, especially when related to an illness like Parkinson’s disease, then you will overestimate the number of people in a room to a greater degree. They also show that if you have hallucinations but are asked to estimate the number of boxes in a room, which are inanimate control objects, then no extra over-estimation occurs, shedding light on the social nature of this overcounting. The results are published in Nature Communications.