Lifeboat Foundation

In news certain to take the bounce out of your step, a NASA scientist says Earth is due for an “extinction-level” event that we basically would have no way of stopping.

Dr. Joseph Nuth of NASA’s Goddard Space Flight Center rang the alarm Monday in San Francisco, New York Magazine reports. The comet that spelled disaster for the dinosaurs hit 65 million years ago, and Nuth said the massive asteroids and comets that could wipe out civilization usually strike “50 to 60 million years apart,” making such an event overdue.

In 2014, scientists first spotted a large comet barreling toward Mars just 22 months before it came perilously close to hitting the planet. That wasn’t enough time to do anything, Nuth said, proof that “the biggest problem, basically, is there’s not a hell of a lot we can do about it at the moment.” To prevent a catastrophic event, Nuth suggests NASA create a rocket that can go in storage, ready to be used if a huge comet comes our way. “It could mitigate the possibility of a sneaky asteroid coming in from a place that’s hard to observe, like from the sun,” Nuth said. The way 2016 has gone so far, you might want to start scanning the sky. Catherine Garcia.

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Amazon said Wednesday it made its first customer delivery by drone, putting the online retailer in the lead to use drones as a new delivery method.

In 2017, AI won’t just be for the nerdy companies. Machine learning can help with mortgage applications and bridge safety, too.

New article on immigration and AI in The Guardian. https://www.theguardian.com/technology/2016/dec/14/donald-tr…automation #future

All of this could be under threat if we are to take some of the comments the Trump campaign made in the run-up to the election at face value. The outspoken candidate claimed that Mark Zuckerberg’s push for specialist H1B visas (the main visa used to hire foreign talent to tech companies) was a threat to jobs for American women and minorities. Meanwhile, Trump’s chief strategist Steve Bannon suggested that Asians have too much power in Silicon Valley.

About a dozen members of Silicon Valley’s elite – including Apple CEO Tim Cook, Alphabet CEO Larry Page, Microsoft CEO Satya Nadella and Facebook COO Sheryl Sandberg – will meet with Trump in New York. The meeting is likely to provide an opportunity for them to highlight their concerns and priorities with the incoming administration.

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Senescent cell removal holds great potential but are all research approaches equal?

Some scientific commentary on senescent cell clearing (Senolytics) and the different approaches the research community is engaged in.

“Researchers are taking two broad approaches to cellular senescence at the present time. The first is to build therapies that can selectively destroy senescent cells, following the SENS rejuvenation model of periodic removal of damage. If the number of senescent cells is managed so as to keep that count low, then they will not cause further harm. This has the advantage of being straightforward and requiring little further research to put into practice. A range of demonstrated treatments and potential treatments already exist — gene therapies, immunotherapies, senolytic drugs, and so forth — and companies such as Oisin Biotechnologies and UNITY Biotechnology are bringing some of these technologies to the clinic.”

Continue reading “Can Cellular Senescence be Reversed in the Near Future, and is Reversal Desirable?” »

Synthetic biology meets senolytics at Lifespan.io

We are developing tools to help researchers accurately target and remove dysfunctional cells in the body that have entered a state called “senescence”, and thereby assist in restoring it to youthful functionality. Please subscribe, share, and fund our campaign today! ►Campaign Link: https://www.lifespan.io/campaigns/cellage-targeting-senescen…c-biology/ ►Subscribe: https://www.youtube.com/user/LifespanIO?sub_confirmation=1

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Dr. Aubrey de Grey from the SENS Research Foundation was kind enough to talk in support of CellAge and their campaign on Lifespan.io

We are developing tools to help researchers accurately target and remove dysfunctional cells in the body that have entered a state called “senescence”, and thereby assist in restoring it to youthful functionality. Please subscribe, share, and fund our campaign today! ►Campaign Link: https://www.lifespan.io/campaigns/cellage-targeting-senescen…c-biology/ ►Subscribe: https://www.youtube.com/user/LifespanIO?sub_confirmation=1

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Cellular senescence is a complicated process but here it is explained in a simple infographic. The removal of senescent cells (senolytics) is a very hot topic right now and it represents the arrival of the first of the SENS therapies.

CellAge is one of the companies engaged in senolytic research and they are running a campaign on Lifespan.io if you would like to learn more about them.

https://www.lifespan.io/campaigns/cellage-targeting-senescen…c-biology/

Continue reading “Senescent cells accumulate with age and gradually poison their neighboring cells and secrete signals that shut down your stem cells and reduce your ability to regenerate tissue” »