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Today, we have an interview with Dr. Michael Bonkowski, an expert on NAD+ biology and aging from the David Sinclair Lab, Harvard Medical School.

Michael Bonkowski aims to advance our understanding of the links between metabolism, aging, and age-associated diseases. He has published 35 peer-reviewed journal articles and has conducted multiple successful longevity studies. In Dr. David Sinclair’s lab, his research efforts are focused on the role of nutrient sensors’ regulation of endocrine signaling and aging in the mouse. He is also working on direct and indirect ways to drive the activity of these nutrient sensors by using dietary manipulations, small molecules, and chemical treatments.

Michael is trained as a pharmacologist, physiologist, and animal scientist. Some of his areas of expertise include animal physiology, genetics, glucose, and insulin homeostasis, metabolism, assay development, protein biochemistry, and transmission electron microscopy imaging.

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Transatomic Power, an MIT spinout that drew wide attention and millions in funding, is shutting down almost two years after the firm backtracked on bold claims for its design of a molten-salt reactor.

High hopes: The company, founded in 2011, plans to announce later today that it’s winding down.

Transatomic had claimed its technology could generate electricity 75 times more efficiently than conventional light-water reactors, and run on their spent nuclear fuel. But in a white paper published in late 2016, it backed off the latter claim entirely and revised the 75 times figure to “more than twice,” a development first reported by MIT Technology Review.

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When you think about the amount of time we spend behind the wheel today, whether in congestion or helping friends and family getting to and forth, being able to spend this time on other activities whilst on the move opens up a whole host of possibilities.

But not only will we have more free time, driverless cars also promise to make our roads safer and make our journeys faster.

Driverless cars are set to arrive on UK roads by 2021 according to the government and are predicted to change the face of personal mobility forever. Looking past the obvious benefits, Select Car Leasing have looked into the less predictable consequences of driverless cars.

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One of the biggest drawbacks of electric vehicles – that they require hours and hours to charge – could be obliterated by new type of liquid battery that is roughly ten times more energy-dense than existing models, according to Professor Lee Cronin, the Regius Chair of Chemistry at the University of Glasgow, UK.

What’s so special about this liquid, or flow, battery?

“A normal electric vehicle has a solid battery, and when that runs out of charge you have to recharge it by plugging it in to a power socket. This takes half an hour or so if you find a rapid charger at a motorway service station, or up to 12 hours at home. Our battery, however, is made of a liquid rather than a solid. If you run out of charge, you could in principle pump out the depleted liquid and – like a regular petrol or diesel vehicle – refill it with liquid that is ready-charged. And that would take minutes.”

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Researchers at the University of Glasgow have developed a small handheld device that can scan for biomarkers to quickly and easily diagnose people with certain diseases and illnesses. Inspired (as always) by Star Trek’s tricorder, the new “multicorder” is designed to help doctors track the presence or progression of an illness from just about anywhere.

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A duty to die at 75 by law?! No need to cure one disease because anyway you will die from another after 65?! A new article uncovers the dangers of going to ‘healthy’ and not longer lifespan:


2) A duty to die becomes greater as you grow older. As we age, we will be giving up less by giving up our lives, if only because we will sacrifice fewer remaining years of life and a smaller portion of our life plans… To have reached the age of, say, seventy-five or eighty years without being ready to die is itself a moral failing, the sign of a life out of touch with life’s basic realities.

3) A duty to die is more likely when you have already lived a full and rich life. You have already had a full share of the good things life offers.

Most bioethicists who denigrate the equal importance of the lives of the elderly and/or who promote age-based health-care-rationing schemes are not as explicit or impolitic in their advocacy as Hardwig. But changing the “primary goal of medicine” to “healthspan” — if involuntary or based on policy — would come perilously close to justifying that same utilitarian end.

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