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Dr. Robert Sapolsky: Science of Stress, Testosterone & Free Will | Huberman Lab Podcast #35

In this episode, I interview Dr. Robert Sapolsky, Ph.D., Professor of Biology, Neurology & Neurosurgery at Stanford University. We discuss stress, what defines short-term versus long-term stress, and how stress can be beneficial or detrimental, depending on the context. We also discuss stress mitigation and how our sense of control over stress mitigation techniques, including exercise, determine health outcomes. Dr. Sapolsky explains some of the key effects of the hormone testosterone — how it can amplify pre-existing tendencies for aggression or sexual behavior, but that it does not produce those behaviors per se. He also explains how testosterone impacts our social hierarchies, sense of confidence, and willingness to embrace challenges of different kinds. He also explains how our behaviors and perceptions shape testosterone levels. And we discuss estrogen and the powerful role it plays in brain development, health and longevity. Finally, we discuss free will, what it means to have free will, and if we have any free will, including how knowledge alone might allow us to make better decisions for ourselves and society.

#HubermanLab #Testosterone #Stress.

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Ned Block — Toward a Science of Consciousness

Watch more interviews on the mystery of consciousness: https://bit.ly/41Bs4NV

How can consciousness be addressed scientifically? The Tucson conference, founded in 1994 and celebrating its 20th anniversary in 2014, exemplifies the quest. What are the range of theories? Where do participants position themselves? Meet the founders, early visionaries, new scientists and thinkers. Progress is being made, but what does this really mean?

Get free access to Closer To Truth’s library of 5,000 videos: https://closertotruth.com/

Support the show with Closer To Truth merchandise: https://bit.ly/3P2ogje.

Ned block is silver professor in the departments of philosophy and psychology and the center for neural science at new york university.

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DeepMind’s New AI made a Breakthrough in Computer Science!

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Mentioned Videos:
AI designing Computer Chips: https://youtu.be/NeHgMaIkPuY
Deepmind AI made a Breakthrough in Math: https://youtu.be/DU6WINoehrg.

Deepmind Paper “Faster sorting algorithms discovered using deep reinforcement learning”:
https://www.nature.com/articles/s41586-023-06004-9

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Dr. Michael Roberts, Ph.D. — Chief Science Officer, International Space Station National Laboratory

Dr. Michael Roberts, Ph.D. is Chief Science Officer of the International Space Station National Laboratory (https://www.issnationallab.org/), and Vice President at the Center for the Advancement of Science in Space (CASIS — https://www.issnationallab.org/about/center-for-the-advancem…dership/), which as manager of the ISS National Laboratory in partnership with NASA, is responsible to the nation for enabling access to the International Space Station for research, technology development, STEM education, and commercial innovation in space as a public service to foster a scalable and sustainable low Earth orbit economy.

Before joining CASIS in 2013, Dr. Roberts worked as a microbial ecologist, principal investigator, and research group lead in the NASA Advanced Life Support program at the Kennedy Space Center.

Prior to arriving at NASA-KSC in 1999, Dr. Roberts completed an undergraduate degree in biology at Maryville College, a doctorate in microbiology at Wesleyan University and post-doctoral research at the Center for Microbial Ecology at Michigan State University and the RIKEN Institute in Wako-shi, Japan.

Consciousness in a Rotor? Science and Ethics of Potentially Conscious Human Cerebral Organoids

Human cerebral organoids are three-dimensional biological cultures grown in the laboratory to mimic as closely as possible the cellular composition, structure, and function of the corresponding organ, the brain. For now, cerebral organoids lack blood vessels and other characteristics of the human brain, but are also capable of having coordinated electrical activity. They have been usefully employed for the study of several diseases and the development of the nervous system in unprecedented ways. Research on human cerebral organoids is proceeding at a very fast pace and their complexity is bound to improve. This raises the question of whether cerebral organoids will also be able to develop the unique feature of the human brain, consciousness. If this is the case, some ethical issues would arise. In this article, we discuss the necessary neural correlates and constraints for the emergence of consciousness according to some of the most debated neuroscientific theories. Based on this, we consider what the moral status of a potentially conscious brain organoid might be, in light of ethical and ontological arguments. We conclude by proposing a precautionary principle and some leads for further investigation. In particular, we consider the outcomes of some very recent experiments as entities of a potential new kind.

3 Advances in Philosophy That Made Science Better

Philosophy is often ridiculed by scientists as being little more than armchair speculation. Stephen Hawking famously declared it “dead.” This is unfortunate because the scientific method itself is a manifestation of philosophical thought arising from the subdiscipline known as epistemology. Historically, science and philosophy have worked hand-in-glove to advance our understanding of the world. In fact, “science” went by the moniker “natural philosophy” for much of history.

Scientists perhaps should be a bit more grateful. Advances in social and political philosophy helped prevent some scientists who upset the established order from being executed — but that’s a discussion for another day. Here, we will examine three philosophical insights that directly led to advances in how science is performed.

What makes science different from everything else?” is inherently a philosophical question. That means that philosophy helps define what science is. This is important because, to learn about the world, we need to be sure of the validity of our methods. For most of the history of Western philosophy, Aristotle’s ideas reigned supreme. While Aristotle’s idea of finding causes through science was largely based on deductive reasoning, experimentation was not seen as a vital part of science.

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