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- @ClubOfINFO — A recent massive leap forward in synthetic life, recently published in Nature, is the expansion of the alphabet of DNA to six letters rather than four, by synthetic biologists – the technicians to whom we entrust the great task of reprogramming life itself.

Breakthroughs such as the above are quite certain to alert more and more people to synthetic biology and its possible consequences. For as long as such breathtaking discoveries continue to be made in this area of research, it is inevitable that latent fears among society will come closer to the surface.
There is likely to be a profound distrust, whether inculcated by religion or by science fiction horror movies and literature, towards the concept of tampering with nature and especially the very building blocks that brought us into existence. While the people with this profoundly negative reaction are not sure what they are warning against, they are motivated by a vitalistic need to believe that the perversion of life is going to provoke hidden – almost divine – repercussions.
Is it really true that no-one should be meddling with something so fundamental to life, or is synthetic biology the science of our century, our civilization’s key to unlimited energy? Whatever the answer may be, the science enabling it already exists and is growing rapidly, and history seems to show that any technology once invented is impossible to contain.
The fact that synthetic base pairs now exist should confirm, for many, the beginning of humanity’s re-engineering of the structures of life itself. As it is unprecedented in our evolution, we are presented with an ethical question and all points of view should be considered, no matter how radical or conservative they are.
It is hard to find a strong display of enthusiasm for the use of synthetic biology as a solution to the world’s greatest problems, even among the transhumanists and techno-progressives. Most of the popular enthusiasm for technological change, particularly the radical improvement of life and the environment through technology, focuses on artificial intelligence, nanotechnology, and things like solar cells as the solution to energy crises. There is not much of a popular case being made for synthetic biology as one of the keys to civilization’s salvation and humanity’s long-term survival, but there should be. The first obstacles to such a case are most likely fear and prejudice.
Even among those theorists who offer the most compelling arguments about self-sustaining technologies and their potential to democratize and change the means of production, enthusiasm for synthetic biology is purposely withheld. Yannick Rumpala’s paper Additive manufacturing as global remanufacturing of politics has a title that speaks for itself. It sees in 3d printing the potential to exorcize some of the most oppressive structural inevitabilities of the current division of labor, transforming economics and politics to be more network-based and egalitarian. When I suggested to Yannick that synthetic organisms – the most obvious choices of technology that will be able to self-replicate and become universally available at every stratum of global society – he was reserved. This was half due to not having reflected on biotechnology’s democratic possibilities, and half due to a principled rejection of “artificial environments”.
Should synthetic biology make people nervous rather than excited, and should be it be rejected as controversial and potentially dangerous rather than embraced as a potentially world-changing and highly democratic technology? The second tendency that results in a rejection of synthetic biology by those who normally go about endorsing technology as the catalyst for social change is the tendency to point to a very specific threat – a humanity-threatening virus.
This second rejection of synthetic biology is easier to respond to than the first, because it is very specific. In fact, the threat is discussed in sufficient depth by synthetic biology’s own leading scientist himself, J. Craig Venter, in his 2013 book Life at the Speed of Light. In anticipation of a viral threat, “bio-terror” is considered the top danger by the US government, but “bio-error” is seen by Venter as an even bigger danger. There is a possibility of individual accidents using synthetic biology, analogous to medical accidents from overdoses. It could involve a virus introduced as a treatment for cancer becoming dangerous (like in the movie, I Am Legend). This is especially possible, if the technology becomes ubiquitous and “DIY”, with individuals customizing their own treatments by synthesizing viruses. However, many household materials and technologies already present the same level of threat to lone individuals, so there is no reason to focus on the popular use of synthetic biology as an extraordinary threat.
A larger scale disaster is far easier to prevent than the death or illness of a lone individual from his own synthetic biology accident. A bio-terror attack, Venter writes, would be extremely difficult using synthetic biology. Synthetic biology is going to give medical professionals the ability to quickly sequence genomes and transmit them on the airwaves to synthesize new vaccines. This would only make it easier to fight against bioterror or a potentially apocalyptic virus, as the threat could be found and sequenced by computers, with the cure being synthesized and introduced almost immediately. Despite this fact that synthetic biology provides the best defense against its own possible threats, it is still important to be balanced in our recognition of the benefits and threats of this technology.
More dangerous than a virus breaking loose from the lab, Venter recognizes the potential for the abuse of synthetic biology by hostile governments. Of most concern, custom viruses could be used as assassins against individuals, whether by governments or conspirators. A cold could be created to have no effect on most people, but be deadly to the President of the United States. All you would need to do is get access to a sample of the President’s genetic material, sequence it, and develop a corresponding virus that exploits a unique weakness in his/her DNA. This danger in particular seems to be more worthy of concern than an apocalyptic virus or devastating bioterrorist attack striking the whole of humanity.
The ethical burden on those who work with synthetic life, as Venter takes from a US government bioethics study, requires “a balance between the pessimistic view of these efforts as yet another example of hubris and the optimistic view of their being tantamount to “human progress” ”. Synthetic biologists must be “good stewards”, and must “move genomic research forward with caution, armed with insights from value traditions with respect to the proper purposes and uses of knowledge.”
However, there is also an undeniable reason to embrace synthetic biology as a solution to many of the world’s most urgent problems. J. Craig Venter’s own words confirm that synthetic life deserves to be included in Yannick Rumpala’s analysis, as a democratic technology that can transform global politics and economics and counter disparity in the world:

“Creating life at the speed of light is part of a new industrial revolution that will see manufacturing shift away from the centralized factories of the past to a distributed, domestic manufacturing future, thanks to 3-d printers.”

There may be a terrible threat from synthetic biology, but it will not necessarily be bio-error or bio-terror. The abuse could come from none other than a very familiar leviathan that has already violated the trust of its citizens before: the supposedly incorruptible United States government. Already, there is an interest in sequencing everyone’s genomes and placing them on a massive database, ostensibly for medical purposes. One cannot help but connect this with the US government’s fascination with tracking and monitoring its own citizens. If the ability to customize a virus to target an individual is true, the killer state will almost certainly maintain the military option of synthetic biology on the table – a possible way of carrying out “targeted killings” around the world in a more sophisticated and secretive manner than ever before.
The threats of synthetic biology are elusive and verge on being conspiracy theories or overused movie plots, but the magnificent potential of synthetic biology to eliminate inequality and suffering in the world is clear and present. In fact, the greatest bio-disaster in the history of the world may be humanity’s reluctance to remanufacture life in order to make more efficient use of the world’s declining natural resources. At the same time, the belief that ubiquitous synthetic biology will threaten life is secondary and distracting, as the true responsibility for unjustly threatening life is likely to always be with the state.

By Harry J. BenthamMore articles by Harry J. Bentham

Originally published on 13 May 2014 at the Institute for Ethics and Emerging Technologies (IEET)

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The Lifeboat Foundation Worldwide Ambassador Mr. Andres Agostini’s own Applied Non-Theological Omniscience defined:

Applied Non-Theological Omniscience defined:

“… Applied non-theological omniscience consists of having total knowledge; knowing everything, having infinite knowledge, the current state of knowledge, the ability to know anything that one chooses to know and can be known and actually knowing everything that can be known. Synonyms to omniscience include panshopy, polyhistory and all-knowingness …”

Transformative and Integrative Risk Management (TAIRM) methodology, under applied omniscience, is the theme of the White Swan idea.

The Lifeboat Foundation Worldwide Ambassador Mr. Andres Agostini’s own Transformative and Integrative Risk Management (TAIRM) methodology and White Swan defined:

“…Transformative and Integrative Risk Management (TAIRM) methodology, a most advanced beyond-insurance risk management systems, comprises of all activities and initiatives required to seize the optimum degree of risk ( a ) elimination, ( b ) mitigation, ( c ) modulation or ( d ) control within the constraints of ( i ) operational effectiveness, ( ii ) time, and ( iii ) cost, attained through the specific, systemic and systematic application of management, scientific, engineering and applied mathematical principles throughout all phases and facets of system operation, articulated under ( 1 ) Systems Approach, ( 2 ) Engineering, ( 3 ) Classical Risk Management and ( 4 ) Practical Non-Theological Omniscience…”

Transformative and Integrative Risk Management (TAIRM) methodology is the theme of the White Swan idea.

Applied Non-Theological Omniscience defined:

“… Applied non-theological omniscience consists of having total knowledge; knowing everything, having infinite knowledge, the current state of knowledge, the ability to know anything that one chooses to know and can be known and actually knowing everything that can be known. Synonyms to omniscience include panshopy, polyhistory and all-knowingness …”

White Swan Update by Andres Agostini at https://lifeboat.com/blog/2014/04/white-swan

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But What Would the End of Humanity Mean for Me? http://www.theatlantic.com/health/archive/2014/05/but-what-d…me/361931/

This Is Your Brain on Gluten
http://www.theatlantic.com/health/archive/2013/12/this-is-yo…en/282550/

This Project Aims To Create Virtual Avatars Of Us All
http://bigthink.com/ideafeed/this-project-aims-to-create-vir…-of-us-all

How Do We Build Ethical Robots?
http://bigthink.com/ideafeed/how-do-we-build-ethical-robots

Americans Can Now Make Political Donations Using Bitcoin
http://bigthink.com/ideafeed/americans-can-now-make-politica…feedburner

In silico: First steps towards a computer simulation of the human body
http://www.independent.co.uk/life-style/health-and-families/…40781.html

A Potent Source Of Genetic Variation In Cognitive Ability Has Just Been Discovered http://www.businessinsider.com/a-potent-source-of-genetic-va…2014-5

Nokia investing $100M in smart-car technology
http://www.cnet.com/news/nokia-investing-100m-in-smart-car-technology/

Ten things you need to know about the Internet of Things http://www.theguardian.com/technology/2014/apr/09/the-intern…ed-to-know

Patented Hydrogen Engine Ready to Power the Future http://www.21stcentech.com/patented-hydrogen-engine-ready-power-future/

Money laundering, counterfeit money: possible solution http://www.datasciencecentral.com/forum/topics/money-launder…e-solution
5 Big Data Use Cases To Watch
http://www.informationweek.com/big-data/big-data-analytics/5…id/1251031

The White Swan Treatise at https://lifeboat.com/blog/2014/04/white-swan

transcendence
I recently saw the film Transcendence with a close friend. If you can get beyond Johnny Depp’s siliconised mugging of Marlon Brando and Rebecca Hall’s waddling through corridors of quantum computers, Transcendence provides much to think about. Even though Christopher Nolan of Inception fame was involved in the film’s production, the pyrotechnics are relatively subdued – at least by today’s standards. While this fact alone seems to have disappointed some viewers, it nevertheless enables you to focus on the dialogue and plot. The film is never boring, even though nothing about it is particularly brilliant. However, the film stays with you, and that’s a good sign. Mark Kermode at the Guardian was one of the few reviewers who did the film justice.

The main character, played by Depp, is ‘Will Caster’ (aka Ray Kurzweil, but perhaps also an allusion to Hans Castorp in Thomas Mann’s The Magic Mountain). Caster is an artificial intelligence researcher based at Berkeley who, with his wife Evelyn Caster (played by Hall), are trying to devise an algorithm capable of integrating all of earth’s knowledge to solve all of its its problems. (Caster calls this ‘transcendence’ but admits in the film that he means ‘singularity’.) They are part of a network of researchers doing similar things. Although British actors like Hall and the key colleague Paul Bettany (sporting a strange Euro-English accent) are main players in this film, the film itself appears to transpire entirely within the borders of the United States. This is a bit curious, since a running assumption of the film is that if you suspect a malevolent consciousness uploaded to the internet, then you should shut the whole thing down. But in this film at least, ‘the whole thing’ is limited to American cyberspace.

Before turning to two more general issues concerning the film, which I believe may have led both critics and viewers to leave unsatisfied, let me draw attention to a couple of nice touches. First, the leader of the ‘Revolutionary Independence from Technology’ (RIFT), whose actions propel the film’s plot, explains that she used to be an advanced AI researcher who defected upon witnessing the endless screams of a Rhesus monkey while its entire brain was being digitally uploaded. Once I suspended my disbelief in the occurrence of such an event, I appreciate it as a clever plot device for showing how one might quickly convert from being radically pro- to anti-AI, perhaps presaging future real-world targets for animal rights activists. Second, I liked the way in which quantum computing was highlighted and represented in the film. Again, what we see is entirely speculative, yet it highlights the promise that one day it may be possible to read nature as pure information that can be assembled according to need to produce what one wants, thereby rendering our nanotechnology capacities virtually limitless. 3D printing may be seen as a toy version of this dream.

Now on to the two more general issues, which viewers might find as faults, but I think are better treated as what the Greeks called aporias (i.e. open questions):

(1) I think this film is best understood as taking place in an alternative future projected from when, say, Ray Kurzweil first proposed ‘the age of spiritual machines’ (i.e. 1999). This is not the future as projected in, say, Spielberg’s Minority Report, in which the world has become so ‘Jobs-ified’, that everything is touch screen-based. In fact, the one moment where a screen is very openly touched proves inconclusive (i.e. when, just after the upload, Evelyn impulsively responds to Will being on the other side of the interface). This is still a world very much governed by keyboards (hence the symbolic opening shot where a keyboard is used as a doorstop in the cyber-meltdown world). Even the World Wide Web doesn’t seem to have the prominence one might expect in a film where computer screens are featured so heavily. Why is this the case? Perhaps because the script had been kicking around for a while (which is true). This may also explain why in Evelyn’s pep talk to funders includes a line about Einstein saying something ‘nearly fifty years ago’. (Einstein died in 1955.) Or, for that matter, why the FBI agent (played by Irish actor Cillian Murphy) looks like something out of a 1970s TV detective series, the on-site military commander looks like George C. Scott and the great quantum computing mecca is located in a town that looks frozen in the 1950s. Perhaps we are seeing here the dawn of ‘steampunk’ for the late 20th century.

(2) The film contains heavy Christian motifs, mainly surrounding Paul Bettany’s character, Max Waters, who turns out to be the only survivor of the core research team involved in uploading consciousness. He wears a cross around his neck, which pops up at several points in the film. Moreover, once Max is abducted by RIFT, he learns that his writings querying whether digital uploading enhances or obliterates humanity have been unwittingly inspirational. Max and Will can be contrasted in terms of where they stand in relation to the classic Faustian bargain: Max refuses what Will accepts (quite explicitly, in response to the person who turns out to be his assassin). At stake is whether our biblically privileged status as creatures entitles us to take the next step to outright deification, which in this case means merging with the source of all knowledge on the internet. To underscore the biblical dimension of dilemma, toward the end of the film, Max confronts Evelyn (Eve?) with the realization that she was the one who nudged Will toward this crisis. Yet, the film’s overall verdict on his Faustian fall is decidedly mixed. Once uploaded, Will does no permanent damage, despite the viewer’s expectations. On the contrary, like Jesus, he manages to cure the ill, and even when battling with the amassed powers of the US government and RIFT, he ends up not killing anyone. However, the viewer is led to think that Will 2.0 may have overstepped the line when he revealed his ability to monitor Evelyn’s thoughts. So the real transgression appears to lie in the violation of privacy. (The Snowdenistas would be pleased!) But the film leaves the future quite open, as what the viewer sees in the opening and final scenes looks more like the result of an extended blackout (and hints are given that some places have already begun the restore their ICT infrastructure) than anything resembling irreversible damage to life as we know it. One can read this as either a warning shot to greater damage ahead if we go down the ‘transcendence’ route, or that such a route might be worth pursuing if we get manage to sort out the ‘people issues’. Given that Max ends the film by eulogising Will and Evelyn’s attempts to benefit humanity, I read the film as cautiously optimistic about the prospects for ‘transcendence’, where the film’s plot is taken as offering a simulated trial run.

My own final judgement is that this film would be very good for classroom use to raise the entire range of issues surrounding what I have called ‘Humanity 2.0’.

WHITE SWAN GRAPHICS BY MR. ANDRES AGOSTINI. — QUESTION: IN CORPORATE SETTINGS, IS THERE AN OUTRIGHT COUNTERMEASSURING WHITE SWAN TO THE BLACK SWAN? READ at https://lifeboat.com/blog/2014/04/White-Swan

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001a  from Profitable Challenges

WHITE SWAN GRAPHICS BY MR. ANDRES AGOSTINI. — QUESTION: IN CORPORATE SETTINGS, IS THERE AN OUTRIGHT COUNTERMEASSURING WHITE SWAN TO THE BLACK SWAN? READ at https://lifeboat.com/blog/2014/04/White-Swan

Mr. Andres Agostini

Lifeboat Foundation Worldwide Ambassador: https://lifeboat.com/ex/bios.andres.agostini

The White Swan Treatise at https://lifeboat.com/blog/2014/04/white-swan

The « … The Human Race to the Future … » Worldwide Ambassador at http://amzn.to/19H3qf0 POINT OF CONTACT AND QUERY: www.linkedin.com/in/andresagostini PROFESSIONAL SERVICE: http://ThisSuccess.wordpress.com

Yesterday’s program, The Next Space Race, on Bloomberg TV was an excellent introduction to the commercial aerospace companies, SpaceX, the Sierra Nevada Company (SNC), and Boeing. The following are important points, at the stated times, in the program:

0.33 mins: The cost of space travel has clipped our wings.
5:18 mins: How many people knew Google before they started?
7:40 mins: SpaceX costs, full compliment, 4x per year at $20 million per astronaut.
11:59 mins: Noisy rocket launch, notice also the length of the hot exhaust is several times the length of the rocket.
12:31 mins: One small step for man, one giant leap for mankind.
12:37 mins: Noisy shuttle launch, notice also the length of the hot exhaust is several times the length of the rocket.
13:47 mins: OPF-3, at one time the largest building in the world at 129 million cubic feet.
16:04 mins: States are luring private companies to start up in their states.
16:32 mins: NASA should be spending its money on exploration and missions and not maintenance and operations.
17:12 mins: The fair market value of OPF-3 is about $13.5 million.
17:19 mins: Maintenance cost is $100,000 per month
17:47 mins: Why Florida?
18:55 mins: International Space Station (ISS) cost $60B and if including the Shuttle program, it cost $150B.
19:17 mins: The size of the commercial space launch business.
21:04 mins: Elon Musk has put $100 million of his own money into SpaceX.
21:23 mins: The goals of NASA and private space do not conflict.

Summary:
1. Cost of ISS is $60B, total cost including the Shuttle program is $150B.

2. SpaceX cost is $20M per astronaut (for 7 astronauts) or a launch cost of $140 million per launch at $560 million per year for 4 launches per year.

3. The next space race is about money.

4. NASA will give a multi billion dollar contract to private space companies to ferry humans & cargo into space and back.

5. Orbiter Processing Facility 3 (OPF-3) valued at $13.5million, and an estimated area of 207,000 sq ft gives a value of $65.22/sq ft.

6. With a maintenance costs of $100,000 gives a per sq ft maintenance costs of $0.48/sq ft/month or $5.80/sq ft/year.

7. Another reason for the Cape Canaveral NASA launch site is the mandatory no/low population down range for rocket launches. At Cape Canaveral this down range is the Atlantic Ocean.

The May 2014 Scientific American article, “Super Symmetry, A Crisis in Physics”, got me thinking. If the proton mass is substantially greater that the sum of the masses of the quarks & gluons in the proton then there is an outrageous question regarding the Standard Model.

Before I attempt to answer that question we need to understand the concept of falsifiability.

The reason why I am qualified to ask this outrageous question is because I solved the physics of gravity modification, and falsifiability opens up more avenues for research, more questions and the finally the reasons for the outrageous question.

In April 2012 I met Lisa Randall while book signing at the National Space Symposium, held every April at the Broadmoor Hotel, Colorado Springs, Colorado. She is the Frank B. Baird, Jr., Professor of Science at Harvard University.

She autograph my copy of her book “Warped Passages” and I showed her the proof copy of my book “An Introduction to Gravity Modification, 2nd Edition” with the g=tau.c^2 massless formula for gravitational acceleration, solving the gravity modification physics.

More in the video …