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Ferroelectric Semiconductors Could Mix Memory and Logic

FSJs (Ferroelectric Semiconductor Junction) in neuromorphic chips.


Engineers at Purdue University and at Georgia Tech have constructed the first devices from a new kind of two-dimensional material that combines memory-retaining properties and semiconductor properties. The engineers used a newly discovered ferroelectric semiconductor, alpha indium selenide, in two applications: as the basis of a type of transistor that stores memory as the amount of amplification it produces; and in a two-terminal device that could act as a component in future brain-inspired computers. The latter device was unveiled last month at the IEEE International Electron Devices Meeting in San Francisco.

Ferroelectric materials become polarized in an electric field and retain that polarization even after the field has been removed. Ferroelectric RAM cells in commercial memory chips use the former ability to store data in a capacitor-like structure. Recently, researchers have been trying to coax more tricks from these ferroelectric materials by bringing them into the transistor structure itself or by building other types of devices from them.

In particular, they’ve been embedding ferroelectric materials into a transistor’s gate dielectric, the thin layer that separates the electrode responsible for turning the transistor on and off from the channel through which current flows. Researchers have also been seeking a ferroelectric equivalent of the memristors, or resistive RAM, two-terminal devices that store data as resistance. Such devices, called ferroelectric tunnel junctions, are particularly attractive because they could be made into a very dense memory configuration called a cross-bar array. Many researchers working on neuromorphic- and low-power AI chips use memristors to act as the neural synapses in their networks. But so far, ferroelectric tunnel junction memories have been a problem.

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

A lack of tools to precisely control gene expression has limited our ability to evaluate relationships between expression levels and phenotypes. Here, we describe an approach to titrate expression of human genes using CRISPR interference and series of single-guide RNAs (sgRNAs) with systematically modulated activities. We used large-scale measurements across multiple cell models to characterize activities of sgRNAs containing mismatches to their target sites and derived rules governing mismatched sgRNA activity using deep learning. These rules enabled us to synthesize a compact sgRNA library to titrate expression of ~2,400 genes essential for robust cell growth and to construct an in silico sgRNA library spanning the human genome. Staging cells along a continuum of gene expression levels combined with single-cell RNA-seq readout revealed sharp transitions in cellular behaviors at gene-specific expression thresholds. Our work provides a general tool to control gene expression, with applications ranging from tuning biochemical pathways to identifying suppressors for diseases of dysregulated gene expression.

Sexy robot influencers are taking over Instagram — and coming for your jobs

In reality, Shudu, who has 196,000 followers on Instagram, is more painting than person. She’s a 3D digital animation made by an Englishman named Cameron-James Wilson, who bills his creation as “the world’s first digital supermodel.”

Influencers, beware: hot bots are coming for your jobs. Shudu is representative of a growing crop of beautiful and highly realistic avatars on social media, created for the sole purpose of gaining followers and making money. And it’s working — these otherworldly beauties are landing lucrative partnerships with the biggest names in fashion, such as Balmain, Calvin Klein and Dior. Social-media-savvy celebrities are embracing them as well; Kim Kardashian, Bella Hadid and Zendaya have all appeared in photos and videos with their digital counterparts. Even top modeling agencies, including IMG and Lipps, have signed on to manage the most popular bots.

“Over the past few years, this has really taken off,” Wilson, who runs the virtual-influencer company the Diigitals, tells The Post. Wilson, 30, now controls the careers of seven robot models who, like human influencers, post sponsored content on social media for money. “My company has grown massively. This is a really lucrative industry.”

Hyperuniform disordered waveguides and devices for near infrared silicon photonics

In a new report published on Scientific Reports, Milan M. Milošević and an international research team at the Zepler Institute for Photonics and Nanoelectronics, Etaphase Incorporated and the Departments of Chemistry, Physics and Astronomy, in the U.S. and the U.K. Introduced a hyperuniform-disordered platform to realize near-infrared (NIR) photonic devices to create, detect and manipulate light. They built the device on a silicon-on-insulator (SOI) platform to demonstrate the functionality of the structures in a flexible, silicon-integrated circuit unconstrained by crystalline symmetries. The scientists reported results for passive device elements, including waveguides and resonators seamlessly integrated with conventional silicon-on-insulator strip waveguides and vertical couplers. The hyperuniform-disordered platform improved compactness and enhanced energy efficiency as well as temperature stability, compared to silicon photonic devices fabricated on rib and strip waveguides.

Academic and commercial efforts worldwide in the field of silicon photonics have led to engineer optical data communications at the Terabit-scale at increasingly lower costs to meet the rapidly growing demand in data centers. Explosive growth in cloud computing and entertainment-on-demand pose increasingly challenging costs and energy requirements for , processing and storage. Optical interconnects can replace traditional copper-based solutions to offer steadily increasing potential to minimize latency and , while maximizing the bandwidth and reliability of the devices. Silicon photonics also leverage large-scale, complementary metal-oxide semiconductor (CMOS) manufacturing processes to produce high-performance optical transceivers with high yield at low-cost. The properties allow applications of optical transceivers (fiber optical technology to send and receive data) to be increasingly compelling across shorter distances.

More than three decades ago, physicist Richard Soref identified silicon as a promising material for photonic integration. Leading to the present-day steady development and rapid production of increasingly complex photonic integrated circuits (PICs). Researchers can integrate large numbers of massively-parallel compact energy-efficient optical components on a single chip for cloud computing applications from deep learning to artificial intelligence and the internet of things. Compared to the limited scope of commercial silicon photonic systems, photonic crystal (PhC) architectures promise smaller device sizes, although they are withheld by layout constraints imposed by waveguide requirements along the photonic crystal’s axis. Until recently, photonic band gap (PBG) structures that efficiently guide light were limited to photonic crystal platforms. Now, newer classes of PBG structures include photonic quasicrystals, hyperuniform disordered solids (HUDs) and local self-uniform structures.

Blood Test to Diagnose Brain Cancer in Development

Brain cancer remains challenging to diagnose, due to nonspecific symptoms and a lack of cost-effective tests. A new blood test that uses attenuated total reflection (ATR)-Fourier transform infrared (FTIR) spectroscopy in conjunction with machine learning technology, may help advance the detection of brain cancer.

The patented technology, developed by a team at the University of Strathclyde, uses infrared light to produce a “bio-signature” of a blood sample and applies artificial intelligence to check for the signs of cancer.

The research is published in Nature Communications in a paper titled, “Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer.

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