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A new generative AI approach to predicting chemical reactions improves accuracy and reliability

Many attempts have been made to harness the power of new artificial intelligence and large language models (LLMs) to try to predict the outcomes of new chemical reactions. These have had limited success, in part because until now they have not been grounded in an understanding of fundamental physical principles, such as the laws of conservation of mass.

Now, a team of researchers at MIT has come up with a way of incorporating these physical constraints into a reaction prediction model, and thus greatly improving the accuracy and reliability of its outputs.

The new work is reported in the journal Nature, in a paper by recent postdoc Joonyoung Joung (now an assistant professor at Kookmin University, South Korea); former software engineer Mun Hong Fong (now at Duke University); chemical engineering graduate student Nicholas Casetti; postdoc Jordan Liles; physics undergraduate student Ne Dassanayake; and senior author Connor Coley, who is the Class of 1957 Career Development Professor in the MIT departments of Chemical Engineering and Electrical Engineering and Computer Science.

Inflation without an inflaton! This Model Challenges Big Bang Inflation

A new study suggests the universe didn’t need inflation to begin. Instead, gravitational waves could explain how structure formed in the early cosmos.

Paper link: https://journals.aps.org/prresearch/a

Chapters:
00:00 Introduction.
00:40 The Discovery/Event.
02:42 Scientific Significance & Theories.
04:48 Implications and What’s Next.
07:16 Outro.
07:54 Enjoy.

MUSIC TITLE: Starlight Harmonies.

MUSIC LINK: https://pixabay.com/music/pulses-star
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Researchers pioneer optical generative models, ushering in a new era of sustainable generative AI

In a major leap for artificial intelligence (AI) and photonics, researchers at the University of California, Los Angeles (UCLA) have created optical generative models capable of producing novel images using the physics of light instead of conventional electronic computation.

Published in Nature, the work presents a new paradigm for generative AI that could dramatically reduce energy use while enabling scalable, high-performance content creation.

Generative models, including diffusion models and , form the backbone of today’s AI revolution. These systems can create realistic images, videos, and human-like text, but their rapid growth comes at a steep cost: escalating power demands, large carbon footprints, and increasingly complex hardware requirements. Running such models requires massive computational infrastructure, raising concerns about their long-term sustainability.

Deep learning method enables efficient Boltzmann distribution sampling across a continuous temperature range

A research team has developed a novel direct sampling method based on deep generative models. Their method enables efficient sampling of the Boltzmann distribution across a continuous temperature range. The findings have been published in Physical Review Letters. The team was led by Prof. Pan Ding, Associate Professor from the Departments of Physics and Chemistry, and Dr. Li Shuo-Hui, Research Assistant Professor from the Department of Physics at the Hong Kong University of Science and Technology (HKUST).

Astronomers uncover enormous bubble bigger than our Solar System

A giant bubble of gas and dust surrounds the red supergiant DFK 52, likely created in a powerful outburst 4,000 years ago. Astronomers are baffled at how the star survived without going supernova, and suspect a hidden companion may have played a role. This discovery could reveal clues about the final stages of massive stars.

Astronomers from Chalmers University of Technology, Sweden, have discovered a vast and expanding bubble of gas and dust surrounding a red supergiant star – the largest structure of its kind ever seen in the Milky Way. The bubble, which contains as much mass as the Sun, was blown out in a mysterious stellar eruption around 4,000 years ago. Why the star survived such a powerful event is a puzzle, the scientists say.

The new results are published in the scientific journal Astronomy and Astrophysics, and the team was led by Mark Siebert, Chalmers, Sweden. Using the ALMA radio telescope in Chile, the researchers observed the star DFK 52 – a red supergiant similar to the well-known star Betelgeuse.

Starship IFT-10 & Starlink

SpaceX’s successful Starship IFT-10 test and advancements in Starlink technology are poised to significantly reduce launch costs and disrupt the broadband landscape, paving the way for a more efficient and cost-effective space travel and satellite internet service.

## Questions to inspire discussion.

Starship and Starlink Advancements.

🚀 Q: How does Starship improve Starlink satellite deployment? A: Starship enables deployment of V3 Starlink satellites that are 40-50X cheaper per unit bandwidth compared to Falcon 9, according to Mach33 research.

📡 Q: What advantages do larger satellites on Starship offer? A: Starship’s size allows for larger satellites delivering more bandwidth per mass, improving physics scaling laws and making it 50X more efficient than Falcon 9 for launching bandwidth per kilogram.

Cost and Capacity Improvements.

Uncovering the mysteries of high-temperature cuprate superconductors

In their quest to explore and characterize high-temperature superconductors, physicists have mostly focused on a material that is not the absolute highest. That’s because that crystal is much easier to split into uniform, easily measurable samples. But in 2024, researchers found a way to grow good crystals that are very similar to the highest temperature superconductor.

Now, many from the same group have analyzed these new crystals and determined why the highest temperature superconductor is indeed higher and what details were missed by looking at the more popular crystal. Their work is published in Physical Review Letters.

The cuprate Bi2223, which at (about 100,000 pascals) superconducts at 110 Kelvin (−163°C), has proven easier to study and specify, even though the similar cuprate Hg1223 superconducts at 134 K.

International collaboration doubles detection of cosmic collisions

An international team of researchers has announced a significant advancement in gravitational-wave astronomy, with the detection of 128 new cosmic collisions involving black holes and neutron stars.

This discovery more than doubles the number of known gravitational-wave events and marks a major milestone in our understanding of the universe.

The findings come from the latest data release by the Laser Interferometer Gravitational-Wave Observatory (LIGO) Virgo Gravitational Wave Interferometer (Virgo) Kamioka Gravitational Wave Detector (KAGRA) collaboration, a global network of gravitational-wave observatories.

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