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Sponge Genes Hint at the Origins of Neurons and Other Cells

๐™Ž๐™ฅ๐™ค๐™ฃ๐™œ๐™š ๐™‚๐™š๐™ฃ๐™š๐™จ ๐™ƒ๐™ž๐™ฃ๐™ฉ ๐™–๐™ฉ ๐™ฉ๐™๐™š ๐™Š๐™ง๐™ž๐™œ๐™ž๐™ฃ๐™จ ๐™ค๐™› ๐™‰๐™š๐™ช๐™ง๐™ค๐™ฃ๐™จ ๐™–๐™ฃ๐™™ ๐™Š๐™ฉ๐™๐™š๐™ง ๐˜พ๐™š๐™ก๐™ก๐™จ


A new study of gene expression in sponges reveals the complex diversity of their cells as well as some possibly ancient connections between the nervous, immune and digestive systems.

Multivitamins, but not cocoa, bound for slower brain aging

Taking a daily multivitamin for 3 years is associated with a 60% slower cognitive aging, with the effects particularly pronounced in patients with cardiovascular (CVD) disease, new research suggests.

In addition to testing the effect of a daily multivitamin on cognition, the COSMOS-Mind study also examined the effect of cocoa flavonols, but showed no beneficial effect.

The results โ€œmay have important public health implications, particularly for brain health, given the availability of multivitamins and minerals and their low cost and safety,โ€ said research researcher Laura D. Baker, PhD, professor, Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Scientists May Have Unlocked Function of Mysterious Structure Found on Neurons in the Brain

Unusual clusters on neurons are calcium-signaling โ€œhotspotsโ€ that activate gene transcription, allowing neurons to produce crucial proteins.

For 30 years, mysterious clusters of proteins found on the cell body of neurons in the hippocampus, a part of the brain, both intrigued and baffled James Trimmer.

Now, the distinguished professor of physiology and membrane biology at the UC Davis School of Medicine may finally have an answer. In a new study published in PNAS, Trimmer and his colleagues reveal these protein clusters are calcium signaling โ€œhotspotsโ€ in the neuron that play a crucial role in activating gene transcription.

New neuroscience study finds neighborhood disadvantage is linked to altered brain maturation in adolescence

The Neuro-Network.

๐™‰๐™š๐™ฌ ๐™ฃ๐™š๐™ช๐™ง๐™ค๐™จ๐™˜๐™ž๐™š๐™ฃ๐™˜๐™š ๐™จ๐™ฉ๐™ช๐™™๐™ฎ ๐™›๐™ž๐™ฃ๐™™๐™จ ๐™ฃ๐™š๐™ž๐™œ๐™๐™—๐™ค๐™ง๐™๐™ค๐™ค๐™™ ๐™™๐™ž๐™จ๐™–๐™™๐™ซ๐™–๐™ฃ๐™ฉ๐™–๐™œ๐™š ๐™ž๐™จ ๐™ก๐™ž๐™ฃ๐™ ๐™š๐™™ ๐™ฉ๐™ค ๐™–๐™ก๐™ฉ๐™š๐™ง๐™š๐™™ ๐™—๐™ง๐™–๐™ž๐™ฃ ๐™ข๐™–๐™ฉ๐™ช๐™ง๐™–๐™ฉ๐™ž๐™ค๐™ฃ ๐™ž๐™ฃ ๐™–๐™™๐™ค๐™ก๐™š๐™จ๐™˜๐™š๐™ฃ๐™˜๐™š

๐™‹๐™จ๐™ฎ๐™ฅ๐™ค๐™จ๐™ฉ:

๐˜•๐˜ฆ๐˜ธ ๐˜ณ๐˜ฆ๐˜ด๐˜ฆ๐˜ข๐˜ณ๐˜ค๐˜ฉ ๐˜ฑ๐˜ถ๐˜ฃ๐˜ญ๐˜ช๐˜ด๐˜ฉ๐˜ฆ๐˜ฅ ๐˜ช๐˜ฏ ๐˜‹๐˜ฆ๐˜ท๐˜ฆ๐˜ญ๐˜ฐ๐˜ฑ๐˜ฎ๐˜ฆ๐˜ฏ๐˜ต๐˜ข๐˜ญ ๐˜Š๐˜ฐโ€ฆ See more.


โ€œOur results essentially showed the children who grew up in disadvantaged neighborhoods had brains that looked older than was typical for their age during early adolescenceโ€ฆ Whatโ€™s more, these associations held true even when we accounted for household socioeconomic status and other adversities (such as childhood abuse and neglect), which suggests that neighborhood disadvantage has a unique role to play in brain development.

MDMA-assisted therapy for PTSD edges closer

Phase 3 clinical trials of MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD) are currently underway in the USA, Canada, and Israel.

These trials, led by the Multidisciplinary Association for Psychedelic Studies (MAPS), are the last step in figuring out if this treatment is safe and effective enough for MDMA to be legally prescribed to treat PTSD.

If thereโ€™s a positive result from the trials, this could happen in the USA as soon as 2022.

Algorithms mimic the process of biological evolution to learn efficiently

Uncovering the mechanisms of learning via synaptic plasticity is a critical step towards understanding how our brains function and building truly intelligent, adaptive machines. Researchers from the University of Bern propose a new approach in which algorithms mimic biological evolution and learn efficiently through creative evolution.

Our brains are incredibly adaptive. Every day, we form , acquire new knowledge, or refine existing skills. This stands in marked contrast to our current computers, which typically only perform pre-programmed actions. At the core of our adaptability lies . Synapses are the connection points between neurons, which can change in different ways depending on how they are used. This synaptic plasticity is an important research topic in neuroscience, as it is central to learning processes and memory. To better understand these processes and build adaptive machines, researchers in the fields of neuroscience and (AI) are creating models for the mechanisms underlying these processes. Such models for learning and plasticity help to understand biological information processing and should also enable machines to learn faster.

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