Lifeboat Foundation

A new tool to address loss of proteostasis and destroy target proteins. It could potentially be used to destroy amyloids in Alzheimer’s, Parkinson’s, ALS, heart disease and amyloidosis which are driven by misfolded protein aggregation.

A new therapy could be the basis for addressing one of the primary reasons we age, loss of proteostasis and the resulting accumulation of Amyloidosis. Alzheimer’s, Parkinson’s, Amloidosis, Lipofuscin and so on could all potentially be targets for this technique.

“University of Dundee researchers have shown that it is possible to rapidly target and destroy specific proteins in cells, raising the possibility of developing new ways of targeting ‘undruggable’ proteins in diseases.”

Continue reading “‘Protein missile’ raises possibility of disease breakthroughs” »

For an empirical science, physics can be remarkably dismissive of some of our most basic observations. We see objects existing in definite locations, but the wave nature of matter washes that away. We perceive time to flow, but how could it, really? We feel ourselves to be free agents, and that’s just quaint. Physicists like nothing better than to expose our view of the universe as parochial. Which is great. But when asked why our impressions are so off, they mumble some excuse and slip out the side door of the party.

Physicists, in other words, face the same hard problem of consciousness as neuroscientists do: the problem of bridging objective description and subjective experience. To relate fundamental theory to what we actually observe in the world, they must explain what it means “to observe”—to become conscious of. And they tend to be slapdash about it. They divide the world into “system” and “observer,” study the former intensely, and take the latter for granted—or, worse, for a fool.

A purely atomic explanation of behavior may be just that: an explanation of what atoms do. It would say nothing about brains, much less minds.

Continue reading “A Theory of Consciousness Can Help Build a Theory of Everything” »

https://www.linkedin.com/pulse/spacetech-we-quite-yet-brett-gallie on @LinkedIn

I was recently at NASA’s annual SpaceApps Hackathon and the focus this year was climate change and our team brainstormed solutions to track the causes of devastating Twisters and we noted that technology had not progressed far enough to build our tracking probes but was close to being developed.

Massive technological advances need to be made if we are going to Mars and beyond.

Researches successfully avoided brain-damaging blood loss while the donor head was being attached to the recipient rat.

The world has been gifted, or maybe cursed, with the latest iteration of creepy head transplant experiments.

In a new study published in CNS Neuroscience and Therapeutics, researchers in China grafted the heads of smaller rats onto the necks of larger rats because we all know that rats with two heads are better than rats with one.

Continue reading “Scientists Just Transplanted Small Rat Heads Onto Bigger Rats” »

Another futurist, Dave Evans, founder and CTO of Silicon Valley stealth startup Stringify, gave his thoughts about Kurzweil’s nanobot idea in an interview with James Bedsole on February.

Evans explained that he thinks such a merging of technology and biology isn’t at all farfetched. In fact, he described three stages as to how this will occur: the wearable phase (where we are today), the embeddable phase (where we’re headed, with neural implants and such), and the replaceable phase.

Continue reading “Kurzweil: By 2030, Nanobots Will Flow Throughout Our Bodies” »

The DARPA Targeted Neuroplasticity Training (TNT) program is exploring ways to speed up skill acquisition by activating synaptic plasticity. If the program succeeds, downloadable learning that happens in a flash may be the result.

In March 2016, DARPA — the U.S. military’s “mad science” branch — announced their Targeted Neuroplasticity Training (TNT) program. The TNT program aims to explore various safe neurostimulation methods for activating synaptic plasticity, which is the brain’s ability to alter the connecting points between neurons — a requirement for learning. DARPA hopes that building up that ability by subjecting the nervous system to a kind of workout regimen will enable the brain to learn more quickly.

DARPA announced the Targeted Neuroplasticity Training, or TNT, program last March, and work now has begun on the effort to discover the safest and most effective ways to activate a natural process called “synaptic plasticity.”

Plasticity is the brain’s ability to strengthen or weaken its neural connections to adapt to changes in the environment. For TNT Program Manager Dr. Doug Weber, such plasticity is about learning.

“We’re talking about neural plasticity, or how the neurons, which are the working units in the brain, how their function changes over time as we train on new skills,” he said during a recent interview with DoD News.

Continue reading “DARPA Funds Brain-Stimulation Research to Speed Learning” »

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Memory might form simultaneously in the hippocampus and the cortex, but remain “silent” in the cortex for several weeks before maturing.