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Category: neuroscience – Page 619

Prof. Dr. Andrea B. Maier, MD, PhD — Building A Clinically Credible Platform For Longevity Medicine

Building A Clinically Credible Platform For Longevity Medicine — Prof. Dr. Andrea Maier MD, PhD, National University of Singapore, Centre for Healthy Longevity.

Professor Dr. Andrea B. Maier, MD, Ph.D., is the Oon Chiew Seng Professor in Medicine, Healthy Ageing and Dementia Research, and Co-Director of the Centre for Healthy Longevity, at the National University Of Singapore (https://discovery.nus.edu.sg/19564-andrea-britta-maier).

Professor Maier also holds professorship appointments at VU University Medical Centre — https://research.vu.nl/en/persons/andrea-maier, Amsterdam, Netherlands, and University of Melbourne (https://findanexpert.unimelb.edu.au/profile/773728-andrea-maier), Australia, as well as is Director of Medicine and Community Care at the Royal Melbourne Hospital, Australia.

Professor Maier is also the President of the Australia and New Zealand Society for Sarcopenia and Frailty Research, as well as Founding President of the Healthy Longevity Medicine Society — https://hlms.co/.

A Fellow of the Royal Australasian College of Physicians (FRACP), Professor Maier graduated in Medicine (MD) 2003 from the University of Lübeck (Germany), was registered 2009 in The Netherlands as Specialist in Internal Medicine-Geriatrics and was appointed Full Professor of Gerontology at Vrije Universiteit Amsterdam (The Netherlands) in 2013 where she was the head of Geriatrics at the Vrije Universiteit Medical Center from 2012 to 2016.

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‘Love hormone’ oxytocin may help mend broken hearts (literally), lab study suggests

Oxytocin, sometimes called the “love hormone,” may help heal broken hearts — literally. In a new study of zebrafish and human cells, scientists found that the brain-made hormone may help heart tissue regenerate after injury and, in theory, could someday be used in the treatment of heart attacks, according to the researchers.

Because the new study was conducted in fish tanks and lab dishes, however, this theoretical treatment is still far from realization.

Research team shines light on how the brain stores positive and negative memories

You may not realize it, but each time you recall a memory—like your first time riding a bike or walking into your high school prom—your brain changes the memory ever so slightly. It’s almost like adding an Instagram filter, with details being filled in and information being updated or lost with each recall.

“We’re inadvertently applying filters to our ,” says Steve Ramirez, a Boston University neuroscientist. Even though a filtered memory is different from the original, you can tell what that basic picture is, for the most part, he says.

“Memory is less of a video recording of the past, and more reconstructive,” says Ramirez, a BU College of Arts & Sciences assistant professor of psychological and . The malleable nature of memory is both a blessing and curse: It’s bad if we remember false details, but it’s good that our brains have the natural ability to mold and update memories to make them less potent, especially if it is something scary or traumatic.

Cognitive and Behavioral Neurology

E to forgetting and false memories. However, if we believe that episodic memory developed to flexibly and creatively combine and rearrange memories of prior events in order to plan for the future, then it is quite a good system. We argue that consciousness originally developed as part of the episodic memory system—quite likely the part needed to accomplish that flexible recombining of information. We posit further that consciousness was subsequently co-opted to produce other functions that are not directly relevant to memory per se, such as problem-solving, abstract thinking, and language. We suggest that this theory is compatible with many phenomena, such as the slow speed and the after-the-fact order of consciousness, that cannot be explained well by other theories. We believe that our theory may have profound implications for understanding intentional action and consciousness in general. Moreover, we suggest that episodic memory and its associated memory systems of sensory, working, and semantic memory as a whole ought to be considered together as the conscious memory system in that they, together, give rise to the phenomenon of consciousness. Lastly, we suggest that the cerebral cortex is the part of the brain that makes consciousness possible, and that every cortical region contributes to this conscious memory system…

The Aging Process Is Unstoppable, Or Is It…?

Just a matter of time for people.

Anti-Aging interview with David Sinclair by Mr. Myllet.

BY THE WAY…, I recently signed up for Dr. David Sinclair’s new test that will tell me how fast I’m aging — I thought you would want to know too!
You also can secure your free waiting list spot: https://otrim.ai/YourBiologicalAging.

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Thank you for watching, I´m happy about your interest in Healthy Lifestyle & Longevity!

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New Discovery Means Parkinson’s Could Be Diagnosed With a Swab in Just 3 Minutes

When it comes to developing treatments and eventual cures for diseases, being able to diagnose a condition early and accurately makes a huge difference – and scientists have now developed a quick, reliable method of identifying people with Parkinson’s disease.

The test can be run in as little as 3 minutes after a skin swab has been taken. The swab is analyzed for changes in the chemical mix of sebum, a natural waxy oil produced by the skin that has previously been linked to Parkinson’s.

At the moment, there’s no conclusive test for Parkinson’s disease – specialists look at symptoms, medical history, the results of a lengthy physical examination, and in some cases, a brain scan to diagnose the condition.

Unlocking the Mysteries of Brain Regeneration — Groundbreaking Study Offers New Insight

Because of its distinctive and adorable look, the axolotl Ambystoma mexicanum is a popular pet. Unlike other metamorphosing salamanders, axolotls (pronounced ACK-suh-LAH-tuhl) never outgrow their larval, juvenile stage, a trait known as neoteny. It’s also recognized for its ability to regenerate missing limbs and other tissues including the brain, spinal cord, tail, skin, limbs, liver, skeletal muscle, heart, upper and lower jaw, and ocular tissues like the retina, cornea, and lens.

Mammals, including humans, are almost incapable of rebuilding damaged tissue after a brain injury. Some species, such as fish and axolotls, on the other hand, may replenish wounded brain regions with new neurons.

BI 103 Randal Koene and Ken Hayworth: The Road to Mind Uploading

Patreon support: https://www.patreon.com/braininspired.

Free Video Series: Open Questions in AI and Neuroscience:

BI Workshop- Open Questions Ever

Show notes: https://braininspired.co/podcast/103/

Randal, Ken, and I discuss a host of topics around the future goal of uploading our minds into non-brain systems, to continue our mental lives and expand our range of experiences. The basic requirement for such a subtrate-independent mind is to implement whole brain emulation. We discuss two basic approaches to whole brain emulation. The “scan and copy” approach proposes we somehow scan the entire structure of our brains (at whatever scale is necessary) and store that scan until some future date when we have figured out how to us that information to build a substrate that can house your mind. The “gradual replacement” approach proposes we slowly replace parts of the brain with functioning alternative machines, eventually replacing the entire brain with non-biological material and yet retaining a functioning mind.
Randal and Ken are neuroscientists who understand the magnitude and challenges of a massive project like mind uploading, who also understand what we can do right now, with current technology, to advance toward that lofty goal, and who are thoughtful about what steps we need to take to enable further advancements.

Timestamps.
0:00 — Intro.
6:14 — What Ken wants.
11:22 — What Randal wants.
22:29 — Brain preservation.
27:18 — Aldehyde stabilized cryopreservation.
31:51 — Scan and copy vs. gradual replacement.
38:25 — Building a roadmap.
49:45 — Limits of current experimental paradigms.
53:51 — Our evolved brains.
1:06:58 — Counterarguments.
1:10:31 — Animal models for whole brain emulation.
1:15:01 — Understanding vs. emulating brains.
1:22:37 — Current challenges.

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