Lifeboat Foundation

We all know taking away screens and reading to our children during their formative years is the best thing for their brains. Now, there is new incredible science to back it up. We asked Jessica Ewing, CEO of subscription book club Literati and graduate of Stanford University in Cognitive Science, every question we could think of about kids, brains, and books.

The latest science, as explored by Literati CEO Jessica Ewing.

Scientific studies continue to show us how exercise can bring a range of cognitive benefits, from limiting the risk of Alzheimer’s to giving an immediate boost to our learning capabilities. Researchers working in this area at the University of South Australia have turned their attention to neuroplasticity, finding two styles of workout in particular that give this key brain function the biggest boost.

Neuroplasticity refers to the brain’s ability to rewire the neural connections as we go through life, whether that be in response to certain experiences, building memories, learning new skills or adapting to new environments. In this way, it is seen as critical to the development of a healthy brain from infancy all the way through to adulthood, and the authors of this new study set out to dig into how exercise can influence these vital pathways.

Continue reading “Study pinpoints two workouts that give brain plasticity a big boost” »

A Yale University experiment, led by neuroscientist Nenad Sestanwhich reawakened the brains of slaughtered pigs has raised speculation that human trials could be next, renewing ethical concerns over the pursuit of immortality. In the experiments, the pigs did not regain consciousness but Sestan acknowledged that restoring awareness is a possibility and that the technique could work on humans, keeping the brain alive indefinitely.

Nottingham Trent University ethics researcher Benjamin Curtis says ending up as a disembodied brain might just be a “living hell.” Writing in The Conversation he suggested that living without any actual contact with reality could be a fate worse than death. “Some have argued that even with a fully functional body, immortality would be tedious. With absolutely no contact with external reality, it might just be a living hell,” Curtis wrote.

Curtis explained that the brain is highly integrated with the rest of the body in both humans and animals. It is constantly receiving and sending signals from and to it. “We have no idea what experiences would occur within a disembodied brain. But those experiences may well be deeply disturbing,” he said.

A neuroscientist, he showed how an unrelenting barrage of stress hormones can break down the body, leading to disease, depression, obesity and more.

In a surprising study, Oregon State University researchers found that no matter how much stress they placed on mice from either a high-fat diet or strenuous exercise, the animals’ mitochondria were able to adapt and continue their normal processes.

The findings could have major implications for the study of diseases like diabetes, Parkinson’s and Alzheimer’s, all of which are associated with an impairment in the breaking-down and clearance of damaged mitochondria.

Mitochondria are the structures that house cellular respiration, the process used to turn nutrients into energy. Dysfunction in mitochondria may lead to lower energy production, greater inflammation and tissue damage. Yet as central as mitochondria are to living organisms, scientists still don’t know exactly what keeps them healthy—or makes them unhealthy.

The interactive art pop-up The End of You tackles the environmental crisis through a transhumanistic lens. It’ll even let you morph into a tree. Well, sorta.

A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer’s or cancer from getting into the brain.

Now a team led by researchers at the Georgia Institute of Technology has engineered a way of studying the barrier more closely with the intent of helping drug developers do the same. In a new study, the researchers cultured the human blood-brain barrier on a chip, recreating its physiology more realistically than predecessor chips.

The new chip devised a healthy environment for the barrier’s central component, a brain cell called the astrocyte, which is not a neuron, but which acts as neurons’ intercessors with the circulatory system. Astrocytes interface in human brains with cells in the vasculature called endothelial cells to collaborate with them as the blood-brain barrier.

Identifying biological correlates of late life cognitive function is important if we are to ascertain biomarkers for, and develop treatments to help reduce, age-related cognitive decline. Here, we investigated the associations between plasma levels of 90 neurology-related proteins (Olink® Proteomics) and general fluid cognitive ability in the Lothian Birth Cohort 1936 (LBC1936, N = 798), Lothian Birth Cohort 1921 (LBC1921, N = 165), and the INTERVAL BioResource (N = 4451). In the LBC1936, 22 of the proteins were significantly associated with general fluid cognitive ability (β between −0.11 and −0.17). MRI-assessed total brain volume partially mediated the association between 10 of these proteins and general fluid cognitive ability. In an age-matched subsample of INTERVAL, effect sizes for the 22 proteins, although smaller, were all in the same direction as in LBC1936. Plasma levels of a number of neurology-related proteins are associated with general fluid cognitive ability in later life, mediated by brain volume in some cases.

Important research happening. thank you SENS. if you don’t know what SENS is, take a moment to check them out.

Albert Einstein College of Medicine.