Working out buffs up the body — and perhaps the mind, too.
Category: neuroscience – Page 560
How Grief Rewires The Brain
Posted in neuroscience
Grief can be overwhelming. Here’s what’s going on in the brain when you’re heartsick.
28:49 minutes.
But having strong relationships also means the possibility of experiencing loss. Grief is one of the hardest things people go through in life. Those who have lost a loved one know the feeling of overwhelming sadness and heartache that seems to well up from the very depths of the body.
Scientists at the University of Plymouth are in the early stages of developing tech that would allow humans to control quantum computers with their thoughts.
Within the human brain, neurons perform complex calculations on information they receive. Researchers at MIT have now demonstrated how dendrites—branch-like extensions that protrude from neurons—help to perform those computations.
The researchers found that within a single neuron, different types of dendrites receive input from distinct parts of the brain, and process it in different ways. These differences may help neurons to integrate a variety of inputs and generate an appropriate response, the researchers say.
In the neurons that the researchers examined in this study, it appears that this dendritic processing helps cells to take in visual information and combine it with motor feedback, in a circuit that is involved in navigation and planning movement.
Scientists have uncovered a set of neurons in fruit flies that shut down in cold temperatures and slow reproduction, a system conserved in many insects, including mosquitoes, which could provide a target for pest control.
Their study, published Feb. 16 in the journal Current Biology, takes a step toward understanding how a fly’s brain contributes to sensing the cold and limiting reproduction. Insects and animals, including many mammals, curb reproduction in the winter to protect their newborns from being exposed to harsh winter conditions.
The study has public health and agricultural implications, as tapping into environmentally-dependent mechanisms that influence reproduction in mosquitoes and crop pests may offer new control strategies. Mosquitoes act as reservoirs for the malaria-causing Plasmodium falciparum parasite, which spend the winter inside them.
Neural cell type diversification during development is a complex and highly regulated process. Here, the authors show that the histone H3-lysine 27 demethylase Kdm6b promotes and inhibits the generation of specific motor neuron subtypes during the development of the mouse spinal cord.
You’re not bad at math. Like pearls before swine, your beautiful brain is just far too complex for such basic things. property= description.
There is a cyborg organoid platform developed by integrating “tissue-like” stretchable mesh nanoelectronics with 2D stem cell sheets. Leveraging the 2D-to-3D reconfiguration during organoid development, 2D stem cell sheets fold and embed stretchable mesh nanoelectronics with electrodes throughout the entire 3D organoid. The embedded electronics can then enable continuous electrical recording.
Scientists design stretchable mesh nanoelectronics, mimicking the mechanical and structural properties of brain organoids to build cyborg human brain organoids.
Using the 3D embedded stretchable electrodes, achieved reliable long-term electrical recording of the same hiPSC-derived neural tissue at single-cell, millisecond spatiotemporal resolution for 6 months, revealing the evolution of the tissue-wide single-cell electrophysiology over hiPSC-derived neuron development. Applying this technology to brain organoids at early developmental stages, they traced the gradually emerging single-cell action potentials and network activities.
#biomimicry #meshelectronics #hiPSC #neurallace #neuroscience
About 1 in 300 people in the general population carry the Tay-Sachs disease gene. Ray Kachatorian/Stone via Getty ImagesTwo babies have received the first-ever gene therapy for Tay-Sachs disease after over 14 years of development. Tay-Sachs is a severe neurological disease caused by a deficiency in an enzyme called HexA. This enzyme breaks down a fatlike substance that normally exists in very small, harmless amounts in the brain. Without HexA, however, this fatlike substance can accumulate to toxic levels that damage and kill neurons.