An innovative microscopy technique bridges the gap between field of view and resolution.
Category: neuroscience – Page 381
Analysis of intracranial EEG from epilepsy patients suggests three neural patterns associated with spatial attention and consciousness, and implicate high-level visual areas and lateralized fronto-parietal networks in shaping human conscious experience.
Click image for animation of DBS for post-stroke rehabilitation
A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients by Cleveland Clinic researchers has shown that using DBS to target the dentate nucleus – which regulates fine-control of voluntary movements, cognition, language, and sensory functions in the brain – is safe and feasible.
The EDEN trial (Electrical Stimulation of the Dentate Nucleus for Upper Extremity Hemiparesis Due to Ischemic Stroke) also shows that the majority of participants (nine out of 12) demonstrated improvements in both motor impairment and function. Importantly, the study found that participants with at least minimal preservation of distal motor function at enrollment showed gains that almost tripled their initial scores.
New work led by researchers at the University of Exeter, King’s College London, the London School of Hygiene and Tropical Medicine and the University of Liverpool has found that women who had at least one contact with mental health services in the seven years prior to their pregnancy were at increased risk of preterm birth.
The study, “Obstetric and neonatal outcomes in pregnant women with and without a history of specialist mental health care: a national population-based cohort study using linked routinely collected data in England,” published in Lancet Psychiatry, analyzed data from more than two million pregnant women, and found that one in 10 women who had used mental health services before their pregnancy had a preterm birth, compared to one in 15 in those who had not.
Researchers also found that women who had used mental health services faced a higher risk of giving birth to a baby that was small for its gestational age, increasing from 65 per 1,000 births in women who had not used mental health services to 75 per 1,000 births in women who had.
We’re seeing major advancements in tech that can decode brain signals, interpreting neural activity to reveal what’s on someone’s mind, what they want to say, or – in the case of a new study – which song they’re listening to.
US researchers have been able to reconstruct a “recognizable version” of a Pink Floyd song based on the pulses of activity moving through a specific part of the brain’s temporal lobe in volunteers as they listened to the hit Another Brick in the Wall Part 1.
While the tune in question did go through some initial processing into a spectrogram form to be more compatible with the brain’s audio processing techniques, the reverse process is impressive in terms of its fidelity.
Dr. Howard Tucker has been practicing medicine and neurology for over 75 years. The 101-year-old doctor shares his No. 1 secret for keeping your brain sharp.
Blood vessels form the transportation network within our bodies. They are streets where red and white blood cells drive. They are the delivery system to oxygenate our brain and other vital organs and muscles. There are other highways in our bodies such as our nervous and lymphatic systems, but blood vessels are the ones that are central to healthy heart function and keeping our brain supplied with oxygen. When blood vessels are compromised we can suffer a stroke, heart attack, aneurysm or die.
When usual causes of heart attacks are blocked coronary arteries. The coronary arteries supply blood and oxygen to the heart. When partially blocked people experience symptoms like angina. When blocked they can suffer a myocardial infarction, the fancy name for a heart attack.
Today, harvested blood vessel grafts from human donors or the patient are used for bypassing coronary blood vessel blockages. But researchers at the University of Melbourne believe that fabricated blood vessel tissue that can be shaped to any need would be an effective substitute for existing grafts. The team in its search for a graft alternative has combined a variety of materials and living tissue with a fabrication technique to create complex blood vessels that can serve multiple purposes.
M3GAN wasn’t malicious. It followed its programming, but without any care or respect for other beings—ultimately including Cady. In a sense, as it engaged with the physical world, M3GAN became an AI sociopath.
Sociopathic AI isn’t just a topic explored in Hollywood. To Dr. Leonardo Christov-Moore at the University of Southern California and colleagues, it’s high time we build artificial empathy into AI—and nip any antisocial behaviors in the bud.
In an essay published last week in Science Robotics, the team argued for a neuroscience perspective to embed empathy into lines of code. The key is to add “gut instincts” for survival—for example, the need to avoid physical pain. With a sense of how it may be “hurt,” an AI agent could then map that knowledge onto others. It’s similar to the way humans gauge each others’ feelings: I understand and feel your pain because I’ve been there before.
Watch the full episode and view show notes here: https://bit.ly/3Oo9mE5
Become a member to receive exclusive content: https://peterattiamd.com/subscribe/
Sign up to receive Peter’s email newsletter: https://peterattiamd.com/newsletter/
In this “Ask Me Anything” (AMA) episode, Peter delves into the realm of genetics, unraveling its connection to disease and emphasizing the value of understanding one’s genetic risks. He elucidates essential background knowledge on genetics before delving into the myriad reasons why individuals might consider genetic testing. Peter differentiates scenarios where genetic testing provides genuine insights from those where it may not be as useful. From there, Peter explores a comprehensive comparison of commercial direct-to-consumer genetic tests, providing insights on interpreting results and identifying the standout options for gaining insights into personal health.
In this sneak peek, we discuss:
00:00 — Intro.
02:09 — Defining the term “genetics” and why it’s important.
04:03 — What is DNA, and how does it impact our biology and traits?
07:13 — How are genetics passed down from parent to child?
11:44 — How much do genes vary across individuals?
16:22 — Which traits are determined by genetics versus experience or environmental factors?
22:30 — Reasons for genetic testing.
In the full episode, we also discuss:
–What exactly is being measured by a genetic test?;
–Testing for monogenic disorders;
–Understanding polygenic risk;
–Is genetic testing more important for someone who doesn’t know their family history?;
–What does it mean to be positive for a particular variant?;
–What does it mean to be negative for a particular variant?;
–How does someone get genetic testing through their healthcare provider, and how are these tests performed?;
–The financial cost of various genetic tests;
–Could having a risk allele for a disease result in an increase in one’s insurance premium?;
–Other risks associated with genetic testing;
–How do commercial, direct-to-consumer genetic tests compare to the information one might receive from clinical genetic testing?;
–Are certain direct-to-consumer tests better than others?;
–How long until whole genome sequencing becomes genuinely useful?;
–How useful are personalized dietary recommendations based on genetics?;
–Final thoughts and advice regarding genetic testing; and.
–More.
——-
About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
A comprehensive new study provides evidence that various personality traits and cognitive abilities are connected. This means that if someone is good at a certain cognitive task, it can give hints about their personality traits, and vice versa.
For example, being skilled in math could indicate having a more open-minded approach to new ideas, but might also be associated with lower levels of politeness. These connections can help us understand why people are different in how they think and act.
The research has been published in the Proceedings of the National Academy of Sciences.