Dec 4, 2022
Swelling along brain’s axons may be true culprit in Alzheimer’s disease
Posted by Shubham Ghosh Roy in categories: biotech/medical, neuroscience
The formation of amyloid plaques in the brain is a hallmark of Alzheimer’s disease. But drugs designed to reduce accumulations of these plaques have so far yielded, at best, mixed results in clinical trials.
Yale researchers have found, however, that swelling caused by a byproduct of these plaques may be the true cause of the disease’s debilitating symptoms, they report Nov. 30 in the journal Nature. And they identified a biomarker that may help physicians better diagnose Alzheimer’s and provide a target for future therapies.
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