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Archive for the ‘neuroscience’ category: Page 343

Feb 6, 2023

The Brain Works Like a Resonance Chamber

Posted by in category: neuroscience

Summary: Using advanced neuroimaging techniques, researchers discovered distant brain regions oscillate together in time.

Source: champalimaud centre for the unknown.

Itโ€™s been over 20 years since neuroimaging studies โ€“ using functional magnetic resonance imaging (fMRI), a widely-used technology to capture live videos of brain activity โ€“ have been detecting brain-wide complex patterns of correlated brain activity that appear disrupted in a wide range of neurological and psychiatric disorders.

Feb 6, 2023

Prolific autism researcher has two dozen papers retracted

Posted by in category: neuroscience

๐๐ซ๐จ๐ฅ๐ข๐Ÿ๐ข๐œ ๐š๐ฎ๐ญ๐ข๐ฌ๐ฆ ๐ซ๐ž๐ฌ๐ž๐š๐ซ๐œ๐ก๐ž๐ซ ๐ก๐š๐ฌ ๐ญ๐ฐ๐จ ๐๐จ๐ณ๐ž๐ง ๐ฉ๐š๐ฉ๐ž๐ซ๐ฌ ๐ซ๐ž๐ญ๐ซ๐š๐œ๐ญ๐ž๐

An autism researcher lost two dozen papers to retraction in January, eight years after the publisher was made aware of potentially troubling editorial practices. Elsevier, the publisher, cited undisclosed conflicts of interest, duplicated methodology and a โ€œcompromisedโ€ peer-review process as reasons for the retractions.

The papers were published in Research in Developmental Disabilities and Research in Autism Spectrum Disorders between 2013 and 2014 โ€” a period when Johnny Matson, then professor of psychology at Louisiana State University (LSU) in Baton Rouge and an author on all of the papers, was editor-in-chief of both journals.

Continue reading “Prolific autism researcher has two dozen papers retracted” »

Feb 6, 2023

Will Revitalizing Old Blood Slow Aging?

Posted by in categories: biotech/medical, life extension, neuroscience

Rejuvenating an older personโ€™s blood may now be within reach, based on recent findings from Passeguรฉโ€™s lab published in Nature Cell Biology(link is external and opens in a new window).

Passeguรฉ, with her graduate student Carl Mitchell, found that an anti-inflammatory drug, already approved for use in rheumatoid arthritis, can turn back time in mice and reverse some of the effects of age on the hematopoietic system.

Nature article:

Continue reading “Will Revitalizing Old Blood Slow Aging?” »

Feb 6, 2023

Depression and Anxiety Exhaust the Heart, Literally

Posted by in categories: biotech/medical, neuroscience

A 1967 publication titled โ€œMortality of Bereavementโ€ discovered that bereaved relatives had a 7-fold increased risk of dying within the following year. Despite that the cause of death was undetermined, this is the first scientific evidence indicating that extreme sadness kills.

Coined in 1991, Takotsubo cardiomyopathy โ€” or broken heart syndrome โ€” mimic aspects of a heart attack such as shortness of breath, fainting, and chest pain. But, oddly, they have no blocked arteries. Instead, some parts of the heart stopped moving and other heart muscles try to compensate for this. This turns the heart into an irregular shape, like that of an octopus pot โ€” hence, the name โ€œTakotsuboโ€ (โ€˜Takoโ€™ means octopus and โ€˜tsuboโ€™ means pot in Japanese). This condition is reversible but can be fatal at times. Takotsubo cardiomyopathy is triggered by intense emotions or stressful life events such as the death of a loved one and losing (or even winning) a lot of money. This is why โ€œheartbrokenโ€ from sadness is a legitimate phenomenon.

Research advances further confirm that sadness, or more accurately emotional stress, destroy the heart in many ways. The mind-heart connection extends to far more than just the broken heart syndrome. Convincing epidemiological evidence ascertains that emotional pains can lead to heart diseases, the major killer worldwide, and this linkage is underpinned by biology.

Feb 5, 2023

Blobs of human brain planted in rats offer new treatment hope

Posted by in categories: biotech/medical, neuroscience

The team behind the work suggest that eventually doctors might be able to grow blobs of brain tissue from a patientโ€™s own cells in the lab and use them to repair brain injuries caused by stroke or trauma.

โ€œThis is incredibly exciting to me as a physician,โ€ said Isaac Chen, a physician and assistant professor of neurosurgery at the University of Pennsylvania.

The study is the latest in the rapidly growing and ethically complex field of brain organoids. Scientists have shown that when cultivated in the right conditions, neurons begin to form tiny brain-like structures, allowing scientists to investigate developmental conditions such as autism and a wide range of basic neuroscience questions.

Feb 5, 2023

Whatโ€™s Next?: The 2023 Healthcare Industry Trend Report

Posted by in categories: biotech/medical, neuroscience, robotics/AI

In 2023, the US healthcare industry is again facing several significant challenges, including ongoing high inflation rates, labor shortages, and the persistent impact of the COVID-19 pandemic. Despite continued difficulties, leaders in the space are working to find innovative solutions to improve the current system while looking ahead at the promising future of medicine that appears to have already arrived.

From artificial intelligence-based medicine to breakthroughs in precision neuroscience, we outline key trends expected to shape the healthcare landscape in 2023 and beyond.

The 2023 Trend Report: Impactful Healthcare Innovations to Watch.

Feb 5, 2023

Goodbye coffee, hello brain stimulation? People are zapping their brains at home to clear brain fog

Posted by in categories: biotech/medical, neuroscience

๐๐ž๐จ๐ฉ๐ฅ๐ž ๐š๐ซ๐ž ๐ณ๐š๐ฉ๐ฉ๐ข๐ง๐  ๐ญ๐ก๐ž๐ข๐ซ ๐›๐ซ๐š๐ข๐ง๐ฌ ๐š๐ญ ๐ก๐จ๐ฆ๐ž ๐ญ๐จ ๐ข๐ฆ๐ฉ๐ซ๐จ๐ฏ๐ž ๐Ÿ๐จ๐œ๐ฎ๐ฌ ๐š๐ง๐ ๐œ๐ฅ๐ž๐š๐ซ ๐›๐ซ๐š๐ข๐ง ๐Ÿ๐จ๐ . ๐๐ฎ๐ญ ๐ข๐ฌ ๐ข๐ญ ๐ฌ๐š๐Ÿ๐ž?

In 2021, Craig Gibbons was diagnosed with Lyme disease. His doctor prescribed him antibiotics, but the medication failed to eliminate one of his most debilitating symptoms: a lasting brain fog that made it difficult for him to focus or recall information.

So he went with a different approach: at-home brain stimulation.

Continue reading “Goodbye coffee, hello brain stimulation? People are zapping their brains at home to clear brain fog” »

Feb 4, 2023

Ideal blood pressure may remodel brain clearance pathways linked to brain health, dementia

Posted by in categories: biotech/medical, health, neuroscience

๐ˆ๐๐ž๐š๐ฅ ๐›๐ฅ๐จ๐จ๐ ๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ฎ๐ซ๐ž ๐ฆ๐š๐ฒ ๐ซ๐ž๐ฆ๐จ๐๐ž๐ฅ ๐›๐ซ๐š๐ข๐ง ๐œ๐ฅ๐ž๐š๐ซ๐š๐ง๐œ๐ž ๐ฉ๐š๐ญ๐ก๐ฐ๐š๐ฒ๐ฌ ๐ฅ๐ข๐ง๐ค๐ž๐ ๐ญ๐จ ๐›๐ซ๐š๐ข๐ง ๐ก๐ž๐š๐ฅ๐ญ๐ก, ๐๐ž๐ฆ๐ž๐ง๐ญ๐ข๐š

๐˜พ๐™ก๐™ค๐™จ๐™š ๐™ง๐™š๐™ซ๐™ž๐™š๐™ฌ ๐™ค๐™› ๐™ˆ๐™๐™„ ๐™จ๐™˜๐™–๐™ฃ๐™จ ๐™›๐™ค๐™ช๐™ฃ๐™™ ๐™ข๐™ค๐™ง๐™š ๐™ž๐™ฃ๐™ฉ๐™š๐™ฃ๐™จ๐™ž๐™ซ๐™š ๐™๐™ž๐™œ๐™ ๐™—๐™ก๐™ค๐™ค๐™™ ๐™ฅ๐™ง๐™š๐™จ๐™จ๐™ช๐™ง๐™š ๐™ฉ๐™ง๐™š๐™–๐™ฉ๐™ข๐™š๐™ฃ๐™ฉ (๐™ฉ๐™–๐™ง๐™œ๐™š๐™ฉ๐™š๐™™ ๐™ฉ๐™ค ๐™–๐™˜๐™๐™ž๐™š๐™ซ๐™š ๐™– ๐™จ๐™ฎ๐™จ๐™ฉ๐™ค๐™ก๐™ž๐™˜ ๐™ฅ๐™ง๐™š๐™จ๐™จ๐™ช๐™ง๐™š ๐™ก๐™š๐™จ๐™จ ๐™ฉ๐™๐™–๐™ฃ 120 ๐™ข๐™ข ๐™ƒ๐™œ) ๐™ฌ๐™–๐™จ ๐™ข๐™ค๐™ง๐™š ๐™š๐™›๐™›๐™š๐™˜๐™ฉ๐™ž๐™ซ๐™š ๐™ฉ๐™๐™–๐™ฃ ๐™– ๐™ก๐™š๐™จ๐™จ-๐™ž๐™ฃ๐™ฉ๐™š๐™ฃ๐™จ๐™š ๐™ฉ๐™ง๐™š๐™–๐™ฉ๐™ข๐™š๐™ฃ๐™ฉ ๐™œ๐™ค๐™–๐™ก ๐™ค๐™› 140 ๐™ข๐™ข ๐™ƒ๐™œ ๐™จ๐™ฎ๐™จ๐™ฉ๐™ค๐™ก๐™ž๐™˜ ๐™ž๐™ฃ ๐™–๐™˜๐™๐™ž๐™š๐™ซ๐™ž๐™ฃ๐™œ ๐™– ๐™ฅ๐™ค๐™จ๐™ž๐™ฉ๐™ž๐™ซ๐™š ๐™จ๐™ฉ๐™ง๐™ช๐™˜๐™ฉ๐™ช๐™ง๐™–๐™ก ๐™˜๐™๐™–๐™ฃ๐™œ๐™š ๐™ž๐™ฃ ๐™ฉ๐™๐™š ๐™—๐™ง๐™–๐™ž๐™ฃโ€™๐™จ ๐™ฅ๐™š๐™ง๐™ž๐™ซ๐™–๐™จ๐™˜๐™ช๐™ก๐™–๐™ง ๐™จ๐™ฅ๐™–๐™˜๐™š๐™จ: ๐™ฅ๐™–๐™ฉ๐™๐™ฌ๐™–๐™ฎ๐™จ ๐™ฉ๐™๐™–๐™ฉ ๐™–๐™ง๐™š ๐™ž๐™ข๐™ฅ๐™ค๐™ง๐™ฉ๐™–๐™ฃ๐™ฉ ๐™ฉ๐™ค ๐™˜๐™ก๐™š๐™–๐™ง๐™ž๐™ฃ๐™œ ๐™ฉ๐™ค๐™ญ๐™ž๐™ฃ๐™จ ๐™–๐™ฃ๐™™ ๐™ค๐™ฉ๐™๐™š๐™ง ๐™—๐™ฎ๐™ฅ๐™ง๐™ค๐™™๐™ช๐™˜๐™ฉ๐™จ.

๐™„๐™› ๐™ฉ๐™๐™š ๐™—๐™ง๐™–๐™ž๐™ฃ ๐™˜๐™–๐™ฃ๐™ฃ๐™ค๐™ฉ ๐™ฅ๐™ง๐™ค๐™ฅ๐™š๐™ง๐™ก๐™ฎ ๐™˜๐™ก๐™š๐™–๐™ง ๐™ข๐™š๐™ฉ๐™–๐™—๐™ค๐™ก๐™ž๐™˜ ๐™—๐™ฎ๐™ฅ๐™ง๐™ค๐™™๐™ช๐™˜๐™ฉ๐™จ, ๐™ฉ๐™๐™š๐™ฎ ๐™–๐™˜๐™˜๐™ช๐™ข๐™ช๐™ก๐™–๐™ฉ๐™š ๐™–๐™ฃ๐™™ ๐™ข๐™–๐™ฎ ๐™˜๐™ค๐™ฃ๐™ฉ๐™ง๐™ž๐™—๐™ช๐™ฉ๐™š ๐™ฉ๐™ค ๐™ฉ๐™๐™š ๐™™๐™š๐™ซ๐™š๐™ก๐™ค๐™ฅ๐™ข๐™š๐™ฃ๐™ฉ ๐™ค๐™› ๐™™๐™š๐™ข๐™š๐™ฃ๐™ฉ๐™ž๐™–, ๐™ง๐™š๐™จ๐™š๐™–๐™ง๐™˜๐™๐™š๐™ง๐™จ ๐™จ๐™–๐™ž๐™™.

Continue reading “Ideal blood pressure may remodel brain clearance pathways linked to brain health, dementia” »

Feb 4, 2023

Clinical trials show encouraging safety profile for brain-computer interface turning thoughts into action

Posted by in categories: biotech/medical, neuroscience, robotics/AI

PROVIDENCE, R.I. [Brown University] โ€” More than two decades ago, a team of Brown University researchers set out with an ambitious goal to provide people with paralysis a revolutionary neurotechnology capable of turning thoughts about movement into actual action, using a tiny device that would one day be implanted in the surface of the brain. Their work led to an ongoing, multi-institution effort to create the BrainGate brain-computer interface, designed to allow clinical trial participants with paralysis to control assistive devices like computers or robotic limbs just by thinking about the action they want to initiate.

Open Access Paper:

https://n.neurology.org/content/early/2023/01/13/WNL.

Continue reading “Clinical trials show encouraging safety profile for brain-computer interface turning thoughts into action” »

Feb 4, 2023

Scientists develop new device to detect brain tumors using urine

Posted by in categories: biotech/medical, nanotechnology, neuroscience

๐‘๐ž๐ฌ๐ž๐š๐ซ๐œ๐ก๐ž๐ซ๐ฌ ๐š๐ญ ๐๐š๐ ๐จ๐ฒ๐š ๐”๐ง๐ข๐ฏ๐ž๐ซ๐ฌ๐ข๐ญ๐ฒ ๐ข๐ง ๐‰๐š๐ฉ๐š๐ง ๐ก๐š๐ฏ๐ž ๐ฎ๐ฌ๐ž๐ ๐š ๐ง๐ž๐ฐ ๐๐ž๐ฏ๐ข๐œ๐ž ๐ญ๐จ ๐ข๐๐ž๐ง๐ญ๐ข๐Ÿ๐ฒ ๐š ๐ค๐ž๐ฒ ๐ฆ๐ž๐ฆ๐›๐ซ๐š๐ง๐ž ๐ฉ๐ซ๐จ๐ญ๐ž๐ข๐ง ๐ข๐ง ๐ฎ๐ซ๐ข๐ง๐ž ๐ญ๐ก๐š๐ญ ๐ข๐ง๐๐ข๐œ๐š๐ญ๐ž๐ฌ ๐ฐ๐ก๐ž๐ญ๐ก๐ž๐ซ ๐ญ๐ก๐ž ๐ฉ๐š๐ญ๐ข๐ž๐ง๐ญ ๐ก๐š๐ฌ ๐š ๐›๐ซ๐š๐ข๐ง ๐ญ๐ฎ๐ฆ๐จ๐ซ. ๐“๐ก๐ข๐ฌ ๐ฉ๐ซ๐จ๐ญ๐ž๐ข๐ง ๐œ๐จ๐ฎ๐ฅ๐ ๐›๐ž ๐ฎ๐ฌ๐ž๐ ๐ญ๐จ ๐๐ž๐ญ๐ž๐œ๐ญ ๐›๐ซ๐š๐ข๐ง ๐œ๐š๐ง๐œ๐ž๐ซ, ๐š๐ฏ๐จ๐ข๐๐ข๐ง๐  ๐ญ๐ก๐ž ๐ง๐ž๐ž๐ ๐Ÿ๐จ๐ซ ๐ข๐ง๐ฏ๐š๐ฌ๐ข๐ฏ๐ž ๐ญ๐ž๐ฌ๐ญ๐ฌ, ๐š๐ง๐ ๐ข๐ง๐œ๐ซ๐ž๐š๐ฌ๐ข๐ง๐  ๐ญ๐ก๐ž ๐ฅ๐ข๐ค๐ž๐ฅ๐ข๐ก๐จ๐จ๐ ๐จ๐Ÿ ๐ญ๐ฎ๐ฆ๐จ๐ซ๐ฌ ๐›๐ž๐ข๐ง๐  ๐๐ž๐ญ๐ž๐œ๐ญ๐ž๐ ๐ž๐š๐ซ๐ฅ๐ฒ ๐ž๐ง๐จ๐ฎ๐ ๐ก ๐Ÿ๐จ๐ซ ๐ฌ๐ฎ๐ซ๐ ๐ž๐ซ๐ฒ. ๐“๐ก๐ข๐ฌ ๐ซ๐ž๐ฌ๐ž๐š๐ซ๐œ๐ก ๐œ๐จ๐ฎ๐ฅ๐ ๐š๐ฅ๐ฌ๐จ ๐ก๐š๐ฏ๐ž ๐ฉ๐จ๐ญ๐ž๐ง๐ญ๐ข๐š๐ฅ ๐ข๐ฆ๐ฉ๐ฅ๐ข๐œ๐š๐ญ๐ข๐จ๐ง๐ฌ ๐Ÿ๐จ๐ซ ๐๐ž๐ญ๐ž๐œ๐ญ๐ข๐ง๐  ๐จ๐ญ๐ก๐ž๐ซ ๐ญ๐ฒ๐ฉ๐ž๐ฌ ๐จ๐Ÿ ๐œ๐š๐ง๐œ๐ž๐ซ. ๐“๐ก๐ž ๐ซ๐ž๐ฌ๐ž๐š๐ซ๐œ๐ก ๐ฐ๐š๐ฌ ๐ฉ๐ฎ๐›๐ฅ๐ข๐ฌ๐ก๐ž๐ ๐ข๐ง ๐€๐‚๐’ ๐๐š๐ง๐จ.

Although early detection of many types of cancer has contributed to the recent increases in cancer survival rates, the survival rate for has remained almost unchanged for over 20 years. Partly this is due to their late detection. Physicians often discover only after the onset of neurological symptoms, such as loss of movement or speech, by which time the tumor has reached a considerable size. Detecting the tumor when it is still small, and starting treatment as soon as possible, should help to save lives.

One possible sign that a person has a brain tumor is the presence of tumor-related extracellular vesicles (EVs) in their urine. EVs are nano-sized vesicles involved in a variety of functions, including cell-to-cell communication. Because those found in patients have specific types of RNA and membrane proteins, they could be used to detect the presence of cancer and its progression.

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