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Archive for the ‘neuroscience’ category: Page 335

Feb 1, 2023

Study: Superconductivity switches on and off in ‘magic-angle’ graphene

Posted by in categories: computing, neuroscience, particle physics

With some careful twisting and stacking, MIT physicists have revealed a new and exotic property in “magic-angle” graphene: superconductivity that can be turned on and off with an electric pulse, much like a light switch.

The discovery could lead to ultrafast, energy-efficient superconducting transistors for neuromorphic devices—electronics designed to operate in a way similar to the rapid on/off firing of neurons in the human brain.

Magic-angle graphene refers to a very particular stacking of graphene—an atom-thin material made from carbon atoms that are linked in a hexagonal pattern resembling chicken wire. When one sheet of graphene is stacked atop a second sheet at a precise “magic” angle, the twisted structure creates a slightly offset “moiré” pattern, or superlattice, that is able to support a host of surprising electronic behaviors.

Feb 1, 2023

Life as a Brain in a Jar

Posted by in categories: futurism, neuroscience

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Science fiction loves to show us disembodied heads or brains floating in jars, but could this be one route to extending our lives? Or could you already be one living in false reality?

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Jan 31, 2023

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Posted by in categories: bioengineering, biotech/medical, neuroscience

Cancer vaccines are an active area of research for many labs, but the approach that Shah and his colleagues have taken is distinct. Instead of using inactivated tumor cells, the team repurposes living tumor cells, which possess an unusual feature. Like homing pigeons returning to roost, living tumor cells will travel long distances across the brain to return to the site of their fellow tumor cells. Taking advantage of this unique property, Shah’s team engineered living tumor cells using the gene editing tool CRISPR-Cas9 and repurposed them to release tumor cell killing agents. In addition, the engineered tumor cells were designed to express factors that would make them easy for the immune system to spot, tag, and remember, priming the immune system for a long-term anti-tumor response.

The team tested their repurposed CRISPR-enhanced and reverse-engineered therapeutic tumor cells (ThTC) in different mice strains, including the one that bore bone marrow, liver, and thymus cells derived from humans, mimicking the human immune microenvironment. Shah’s team also built a two-layered safety switch into the cancer cell, which, when activated, eradicates ThTCs if needed. This dual-action cell therapy was safe, applicable, and efficacious in these models, suggesting a roadmap toward therapy. While further testing and development is needed, Shah’s team specifically chose this model and used human cells to smooth the path of translating their findings for patient settings.

Jan 31, 2023

AI-Powered Brain Implant Smashes Speed Record for Turning Thoughts Into Text

Posted by in categories: biotech/medical, neuroscience

We speak at a rate of roughly 160 words every minute. That speed is incredibly difficult to achieve for speech brain implants.

Decades in the making, speech implants use tiny electrode arrays inserted into the brain to measure neural activity, with the goal of transforming thoughts into text or sound. They’re invaluable for people who lose their ability to speak due to paralysis, disease, or other injuries. But they’re also incredibly slow, slashing word count per minute nearly ten-fold. Like a slow-loading web page or audio file, the delay can get frustrating for everyday conversations.

A team led by Drs. Krishna Shenoy and Jaimie Henderson at Stanford University is closing that speed gap.

Jan 31, 2023

Tuning Into Brainwave Rhythms Speeds up Learning in Adults

Posted by in category: neuroscience

Summary: Tuning into a person’s brain wave cycle before they perform a learning task can dramatically improve the speed at which cognitive skills improve.

Source: University of Cambridge.

Scientists have shown for the first time that briefly tuning into a person’s individual brainwave cycle before they perform a learning task dramatically boosts the speed at which cognitive skills improve.

Jan 31, 2023

MIT neuroscientist shares 4 things she never does to eliminate ‘brain fog and forgetfulness’

Posted by in categories: food, neuroscience

Brain fog can be caused by stress or eating the wrong foods. Neuroscientist Tara Swart Bieber shares how she boosts mental clarity, memory and concentration.

Jan 31, 2023

Scientists Reveal New Potential Therapeutic Targets for Mental and Neurological Disorders

Posted by in categories: biotech/medical, mathematics, media & arts, neuroscience

A recent study from researchers at the University of California, Irvine found that the removal of cilia from the striatum region of the brain negatively impacted time perception and judgement, opening the possibility for new therapeutic targets for mental and neurological conditions such as schizophrenia, Parkinson’s and Huntington’s diseases, autism spectrum disorder.

Autism Spectrum Disorder (ASD) is a complex developmental disorder that affects how a person communicates and interacts with others. It is characterized by difficulty with social communication and interaction, as well as repetitive behaviors and interests. ASD can range from mild to severe, and individuals with ASD may have a wide range of abilities and challenges. It is a spectrum disorder because the symptoms and characteristics of ASD can vary widely from person to person. Some people with ASD are highly skilled in certain areas, such as music or math, while others may have significant learning disabilities.

Jan 31, 2023

Scientists harness light therapy to target and kill cancer cells in world first

Posted by in categories: biotech/medical, neuroscience

Year 2022 😗


Experts believe it is destined to become the world’s fifth major cancer treatment after surgery, chemotherapy, radiotherapy and immunotherapy.

The light-activated therapy forces cancer cells to glow in the dark, helping surgeons remove more of the tumours compared with existing techniques – and then kills off remaining cells within minutes once the surgery is complete. In a world-first trial in mice with glioblastoma, one of the most common and aggressive types of brain cancer, scans revealed the novel treatment lit up even the tiniest cancer cells to help surgeons remove them – and then wiped out those left over.

Continue reading “Scientists harness light therapy to target and kill cancer cells in world first” »

Jan 31, 2023

The Believing Brain: Evolution, Neuroscience, and the Spiritual Instinct

Posted by in categories: evolution, neuroscience

God, they say, is in the details. But could God also be in our frontal lobes? Every culture from the dawn of humankind has imagined planes of existence beyond the reach of our senses, spiritual domains that shape our Earthly experiences. Why do beliefs of the fantastic hold such powerful sway over our species? Is there something in our evolutionary history that points to an answer? Does neuroscience hold the key? Straddling the gap between science and religion, Brian Greene is joined by renowned neuroscientists, anthropologists, and evolutionary biologists, to explore one of the most profound mysteries of our existence.

PARTICIPANTS: Lisa Barrett, Barbara J. King, Zoran Josipovic, Steven Pinker.

Continue reading “The Believing Brain: Evolution, Neuroscience, and the Spiritual Instinct” »

Jan 31, 2023

Distributed harmonic patterns of structure-function dependence orchestrate human consciousness

Posted by in categories: biotech/medical, mathematics, neuroscience

Connectome harmonic decomposition (CHD) generalises the mathematics of the Fourier transform to the network structure of the human brain. The traditional Fourier transform operates in the temporal domain (Fig. 1a): decomposition into temporal harmonics quantifies to what extent the signal varies slowly (low-frequency temporal harmonics) or quickly (high-frequency temporal harmonics) over time (Fig. 1b). Analogously, CHD re-represents a spatial signal in terms of harmonic modes of the human connectome, so that the spatial frequency (granularity) of each connectome harmonic quantifies to what extent the organization of functional brain signals deviates from the organization of the underlying structural network (Fig. 1c, d). Therefore, CHD is fundamentally different from, and complementary to, traditional approaches to functional MRI data analysis. This is because CHD does not view functional brain activity as composed of signals from discrete spatial locations, but rather as composed of contributions from distinct spatial frequencies: each connectome harmonic is a whole-brain pattern with a characteristic spatial scale (granularity)—from an entire hemisphere to just a few millimetres.

On one hand, this means that CHD is unsuitable to address questions pertaining to spatial localisation and the involvement of specific neuroanatomical regions; such questions have been extensively investigated within the traditional framework of viewing brain activity in terms of spatially discrete regions, and several previous studies have implicated specific neuroanatomical regions in supporting consciousness33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49. On the other hand, CHD enables us to consider how brain activity across states of consciousness is shaped by the brain’s distributed network of structural connections, reflecting the contribution of global patterns at different spatial scales—each arising from the network topology of the human connectome. We emphasise that neither approach is inherently superior, but rather they each provide a unique perspective on brain function: one localised, the other distributed.

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