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In a study published in the journal Cell Stem Cell on February 2, researchers show that brain organoids—clumps of lab-grown neurons—can integrate with rat brains and respond to visual stimulation like flashing lights.

Decades of research has shown that we can transplant individual human and rodent neurons into rodent brains, and, more recently, it has been demonstrated that human brain organoids can integrate with developing rodent brains. However, whether these organoid grafts can functionally integrate with the visual system of injured adult brains has yet to be explored.

“We focused on not just transplanting individual cells, but actually transplanting tissue,” says senior author H. Isaac Chen, a physician and Assistant Professor of Neurosurgery at the University of Pennsylvania. “Brain organoids have architecture; they have structure that resembles the brain. We were able to look at individual neurons within this structure to gain a deeper understanding of the integration of transplanted organoids.”

Who was rumored to be a pedophile.

“The over-all number of minds is just one.”

Nature Neuroscience volume 25, page 1,119 (2022) Cite this article.

Bias in juries pose a serious challenge for judges and attorneys to conduct fair, equal and impartial trials. A recent paper published in Social Cognitive and Affective Neuroscience considers the overlap between social cognitive processes such as cultural and racial stereotyping and brain activity associated with bias against defendants accused of severe crimes.

R. McKell Carter, one of the paper’s co-authors, is an assistant professor of psychology and neuroscience at the University of Colorado Boulder. He is an expert on social cognition: the processes of the brain that interpret the actions, intentions and expectations of others.

Carter’s study examines the role of social cognition in crime-type bias, when jurors perceive the prosecutor’s case stronger based on the severity of the charges against the defendant. Using functional magnetic resonance imaging (fMRI) scans on mock jurors, researchers mapped out regions of the brain that activated when jurors were presented with fictional case narratives and evidence.

A team of Stanford scientists claims to have tested a new brain-computer interface (BCI) that can decode speech at up to 62 words per minute, improving the previous record by 3.4 times.

That’d be a massive step towards real-time speech conversion at the pace of natural human conversation.

Max Hodak, who founded BCI company Neuralink alongside Elon Musk, but wasn’t involved in the study, called the research “a meaningful step change in the utility of implanted BCIs” in an email to Futurism.

Artificial intelligence and machine learning have made tremendous progress in the past few years including the recent launch of ChatGPT and art generators, but one thing that is still outstanding is an energy-efficient way to generate and store long-and short-term memories at a form factor that is comparable to a human brain. A team of researchers in the McKelvey School of Engineering at Washington University in St. Louis has developed an energy-efficient way to consolidate long-term memories on a tiny chip.

Shantanu Chakrabartty, the Clifford W. Murphy Professor in the Preston M. Green Department of Electrical & Systems Engineering, and members of his lab developed a relatively simple device that mimics the dynamics of the brain’s synapses, connections between neurons that allows signals to pass information. The artificial synapses used in many modern AI systems are relatively simple, whereas biological synapses can potentially store complex memories due to an exquisite interplay between different chemical pathways.

Chakrabartty’s group showed that their artificial synapse could also mimic some of these dynamics that can allow AI systems to continuously learn new tasks without forgetting how to perform old tasks. Results of the research were published Jan. 13 in Frontiers in Neuroscience.

Summary: Advancements in brain mapping and the development of new digital tools over the past decade have opened the door to exciting new discoveries in neuroscience and brain sciences.

Source: University of Oslo.

A billion people worldwide suffer from brain diseases such as dementia, addiction and depression. Scientists carrying out brain research at UiO are now contributing to a more efficient utilization of research data by developing 3D brain atlases and new analytic tools.

Researchers at the University of Tsukuba have discovered a connection between the risk of functional disability or death in older adults and the distance they are willing to walk or cycle to reach common destinations (such as a friend’s house or a supermarket).

As they age, physical or cognitive decline can make it difficult for some older adults to navigate their community, affecting their quality of life and becoming a burden on society. However, a recent study by researchers at the University of Tsukuba demonstrates that a willingness to travel longer distances by walking or cycling may help reduce the risk of early functional disability and mortality.

A recent study published in Health and Place presents a model linking death and functional disability rates in older adults to the distances they are willing to travel on foot or bicycle for common community trips. The research found that older adults who were only comfortable with short distances – such as 500 meters or less for walking, or 1 kilometer or less for cycling – faced higher risks of functional disability and death.

Sending a jolt of electricity through a person’s brain can do remarkable things. You only have to watch the videos of people with Parkinson’s disease who have electrodes implanted in their brains. They can go from struggling to walk to confidently striding across a room literally at the flick of a switch.

Stimulating certain parts of the brain can bring people in and out of consciousness. Even handheld devices that deliver gentle pulses to the brain can help older people remember things.

Continue reading “Here’s how personalized brain stimulation could treat depression” »