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Archive for the ‘neuroscience’ category: Page 315

Apr 7, 2022

Alzheimer’s researchers are studying the brain’s plumbing

Posted by in categories: biotech/medical, neuroscience

Tweaking it may delay development of the disease | Science & technology.

Apr 7, 2022

Honey might be the key to cooler, more efficient, biodegradable chips

Posted by in categories: computing, engineering, neuroscience, sustainability

These chips might be the future of neuromorphic computing.


Honey could be the next material used to create brain-like computer chips. Its proven practicality marks another step toward creating efficient, renewable processors for neuromorphic computing systems, using biodegradable products.

Research engineers from WSU’s School of Engineering and Computer Science, Feng Zhao and Brandon Sueoka, first processed honey into a solid. Then they jammed it between two electrodes, using a structure design similar to that of a human synapse. They’re known as ‘memristors,’ and are proficient at learning and retaining information just like human neurons.

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Apr 6, 2022

Reconstruction of Largest Single-Neuron Projectome in Mouse Brain

Posted by in category: neuroscience

Summary: Researchers have released a whole-brain projectome consisting of over 6,000 single neurons in the mouse prefrontal cortex.

Source: Chinese Academy of Science.

In a study published in Nature Neuroscience, scientists at the Center for Excellence in Brain Science and Intelligence Technology (CEBSIT) of the Chinese Academy of Sciences, along with their collaborators, reported the first release of a whole-brain projectome comprising over 6,000 single neurons in the mouse prefrontal cortex (PFC), making it the largest database of a whole-brain, single-neuron mouse projectome to date.

Apr 5, 2022

Loss of neurons, not lack of sleep, makes Alzheimer’s patients drowsy

Posted by in categories: biotech/medical, life extension, neuroscience

The lethargy that many Alzheimer’s patients experience is caused not by a lack of sleep, but rather by the degeneration of a type of neuron that keeps us awake, according to a study that also confirms the tau protein is behind that neurodegeneration.

The study’s findings contradict the common notion that Alzheimer’s patients during the day to make up for a bad night of sleep and point toward potential therapies to help these patients feel more awake.

The data came from study participants who were patients at UC San Francisco’s Memory and Aging Center and volunteered to have their sleep monitored with electroencephalogram (EEG) and donate their brains after they died.

Apr 4, 2022

Neuroscientists Are Confident the Secret to Reversing Brain Damage Is Restoring Brain Plasticity

Posted by in category: neuroscience

The Neuro-Network.

𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐀𝐫𝐞 𝐂𝐨𝐧𝐟𝐢𝐝𝐞𝐧𝐭 𝐭𝐡𝐞 𝐒𝐞𝐜𝐫𝐞𝐭 𝐭𝐨 𝐑𝐞𝐯𝐞𝐫𝐬𝐢𝐧𝐠 𝐁𝐫𝐚𝐢𝐧 𝐃𝐚𝐦𝐚𝐠𝐞 𝐈𝐬 𝐑𝐞𝐬𝐭𝐨𝐫𝐢𝐧𝐠 𝐁𝐫𝐚𝐢𝐧 𝐏𝐥𝐚𝐬𝐭𝐢𝐜𝐢𝐭𝐲

𝙁𝙤𝙧 𝙩𝙝𝙚 𝙬𝙤𝙧𝙡𝙙’𝙨 𝙡𝙚𝙖𝙙𝙞𝙣𝙜 𝙣𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨, 𝙩𝙝𝙚 𝙨𝙚𝙘𝙧𝙚𝙩 𝙩𝙤 𝙪𝙣𝙡𝙤𝙘𝙠𝙞𝙣… See more.

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Apr 4, 2022

Life may actually flash before your eyes on death

Posted by in category: neuroscience

Scientists who “accidentally” made the first ever recording of a dying brain saw startling results.


Scientists — who “accidentally” made the first ever recording of a dying brain — saw startling results.

Apr 3, 2022

Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex

Posted by in category: neuroscience

Recent advances in multi-electrode array technology have made it possible to monitor large neuronal ensembles at cellular resolution in animal models. In humans, however, current approaches restrict recordings to a few neurons per penetrating electrode or combine the signals of thousands of neurons in local field potential (LFP) recordings. Here we describe a new probe variant and set of techniques that enable simultaneous recording from over 200 well-isolated cortical singl… See more.


Neuropixels probes were used to simultaneously record from more than 200 cortical neurons in human participants during neurosurgical procedures. The approach could reveal insights underlying human cognition and pathology.

Apr 3, 2022

Watch: Building the Ultimate Brain Map

Posted by in categories: computing, neuroscience

In efforts to construct a map of neural connections in the brain, researchers at the Flatiron Institute’s Center for Computational Neuroscience are turning to a… See more.


Watch: building the ultimate brain map on simons foundation.

Apr 1, 2022

A human genome has finally, fully been decoded

Posted by in categories: biotech/medical, genetics, neuroscience

Further study of newly-sequenced portions of the genome could also help scientists better understand how humans evolved particular traits, such as the bigger brains that sent them down a genetically distinct path from their great ape ancestors.

“The things that make our frontal cortex bigger come from the genes that map in these repetitive regions,” said Evan Eichler, a professor in the department of genome sciences at the University of Washington School of Medicine and also part of the research collaborative.

Advances in genomic sequencing technology could drive a renaissance of medical breakthroughs, the researchers say.

Mar 31, 2022

CRISPR/Cas9-engineered Gad1 elimination in rats leads to complex behavioral changes: implications for schizophrenia

Posted by in categories: biotech/medical, genetics, neuroscience

GABAergic dysfunctions have been implicated in the pathogenesis of schizophrenia, especially the associated cognitive impairments. The GABA synthetic enzyme glutamate decarboxylase 67-kDa isoform (GAD67) encoded by the GAD1 gene is downregulated in the brains of patients with schizophrenia. Furthermore, a patient with schizophrenia harboring a homozygous mutation of GAD1 has recently been discovered. However, it remains unclear whether loss of function of GAD1 leads to the symptoms observed in schizophrenia, including cognitive impairment. One of the obstacles faced in experimental studies to address this issue is the perinatal lethality of Gad1 knockout (KO) mice, which precluded characterization at the adult stage. In the present study, we successfully generated Gad1 KO rats using CRISPR/Cas9 genome editing technology.