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How cholesterol in the brain may accelerate the onset of Alzheimer’s disease

A landmark study has revealed that cholesterol in the brain may play a fundamental role in catalyzing the formation of amyloid beta clusters, thought to be a central mechanism leading to the devastating degenerative symptoms of Alzheimer’s disease.

An international team of researchers, led by the University of Cambridge, set out to uncover what causes amyloid beta proteins to cluster into the plaques that slowly accumulate and cause the primary degenerative symptoms of Alzheimer’s disease.

“The levels of amyloid-beta normally found in the brain are about a thousand times lower than we require to observe it aggregating in the laboratory – so what happens in the brain to make it aggregate?” asks Michele Vendruscolo, lead on the new research.

Yale experiment to reanimate dead brains promises ‘living hell’ for humans

A scientific experiment to reanimate dead brains could lead to humans enduring a ‘fate worse than death,’ an ethics lecturer has warned.

Last month Yale University announced it had successfully resurrected the brains of more than 100 slaughtered pigs and found that the cells were still healthy.

The reanimated brains were kept alive for up to 36 hours and scientists said the process, which should also work in primates, offered a new way to study intact organs in the lab.

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