A newly developed “GPS nanoparticle” injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.
A critical molecule for the metabolism of living organisms has been synthesized for the first time by University of Hawaiʻi at Mānoa researchers at low temperatures (10 K) on ice coated nanoparticles mimicking conditions in deep space, marking a “cool” step in advancing our understanding of the origins of life.
EPFL researchers have discovered that nanoscale devices harnessing the hydroelectric effect can harvest electricity from the evaporation of fluids with higher ion concentrations than purified water, revealing a vast untapped energy potential.
Evaporation is a natural process so ubiquitous that most of us take it for granted. In fact, roughly half of the solar energy that reaches the earth drives evaporative processes. Since 2017, researchers have been working to harness the energy potential of evaporation via the hydrovol~aic (HV) effect, which allows electricity to be harvested when fluid is passed over the charged surface of a nanoscale device. Evaporation establishes a continuous flow within nanochannels inside these devices, which act as passive pumping mechanisms. This effect is also seen in the microcapillaries of plants, where water transport occurs thanks to a combination of capillary pressure and natural evaporation.
Although hydrovoltaic devices currently exist, there is very little functional understanding of the conditions and physical phenomena that govern HV energy production at the nanoscale. It’s an information gap that Giulia Tagliabue, head of the Laboratory of Nanoscience for Energy Technology (LNET) in the School of Engineering, and PhD student Tarique Anwar wanted to fill. They leveraged a combination of experiments and multiphysics modelling to characterize fluid flows, ion flows, and electrostatic effects due to solid-liquid interactions, with the goal of optimizing HV devices.
A group of Tohoku University researchers has developed a theoretical model for a high-performance spin wave reservoir computing (RC) that utilizes spintronics technology. The breakthrough moves scientists closer to realizing energy-efficient, nanoscale computing with unparalleled computational power.
Credit: Springer Nature Limited
Gas stoves emit nanocluster aerosol that may get deep into your respiratory system, study shows. Cooking on your gas stove can emit more nano-sized particles into the air than vehicles that run on gas or diesel, possibly increasing your risk of developing asthma or other respiratory illnesses, a new Purdue University study has found.
Combustion remains a source of air pollution across the world, both indoors and outdoors. We found that cooking on your gas stove produces large amounts of small nanoparticles that get into your respiratory system and deposit efficiently, said Brandon Boor, an associate professor in Purdue’s Lyles School of Civil Engineering, who led this research.
Based on these findings, the researchers would encourage turning on a kitchen exhaust fan while cooking on a gas stove.
The FIT4NANO project has mapped out the expansive applications and future directions of focused ion beam technology, emphasizing its critical role in advancing research and development across multiple disciplines, from microelectronics to life sciences.
Processing materials on the nanoscale, producing prototypes for microelectronics, or analyzing biological samples: The range of applications for finely focused ion beams is huge. Experts from the EU collaboration FIT4NANO have now reviewed the many options and developed a roadmap for the future. The article, published in Applied Physics Review, is aimed at students, users from industry and science as well as research policymakers.
Discovery and Applications.
“But in the process, we also made a major finding: that hydrovoltaic devices can operate over a wide range of salinities, contradicting prior understanding that highly purified water was required for best performance.”
The process can generate power around the clock since evaporation occurs at various temperatures and even at night. The process also occurs across humidities, making it suitable for use across the planet, irrespective of location.
Guanylate binding proteins (GBP) were discovered by YSM’s John MacMicking, PhD, and colleagues over a decade ago as major organizers of cellular immune response.
In a recent study, MacMicking’s team used advanced cryo-and electron microscope technology to visualize in high resolution the way GBPs…
Yale scientists have discovered a family of immune proteins, which they describe as a “massive molecular machine,” that could affect the way our bodies fight infection.
Our immune system mobilizes numerous proteins to detect viruses and bacteria — and to bring them under control. But until recently, limits to research technology have thwarted scientists’ understanding of how to prevent different pathogens from occupying and replicating within specific parts of our cells in the first place.
Harnessing the latest cryo‐electron microscopy techniques to look inside human cells, researchers at the Yale Systems Biology Institute have identified a family of large immune proteins that assemble into a massive signaling platform directly on the surface of microbial pathogens.
Emerging nanotechnology and molecular innovations present promising strategies in combating inflammation and diabetes, aiming to transform treatment methods and improve patient outcomes significantly.
The intersection of nanotechnology and biomedicine has sparked significant advances in the treatment and understanding of both inflammatory and metabolic diseases. These advances have brought about innovative solutions to longstanding medical challenges, such as rheumatoid arthritis (RA) and type 2 diabetes mellitus (T2DM), diseases that collectively affect millions worldwide.
In Nature Physics, the LSU Quantum Photonics Group offers fresh insights into the fundamental traits of surface plasmons, challenging the existing understanding. Based on experimental and theoretical investigations conducted in Associate Professor Omar Magaña-Loaiza’s laboratory, these novel findings mark a significant advancement in quantum plasmonics, possibly the most noteworthy in the past decade.
While prior research in the field has predominantly focused on the collective behaviors of plasmonic systems, the LSU group adopted a distinct approach. By viewing plasmonic waves as a puzzle, they were able to isolate multiparticle subsystems, or break down the puzzle into pieces. This allowed the team to see how different pieces work together and revealed a different picture, or in this case, new behaviors for surface plasmons.
Plasmons are waves that move along the surface of metals when light is coupled to charge oscillations. Much like tossing pebbles into water generates ripples, plasmons are “ripples” traveling along metal surfaces. These minute waves operate on a nanometer scale, rendering them crucial in fields such as nanotechnology and optics.
