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Solid-State Nanopores Unravel Twisted DNA Mystery

Cancer thrives when mutated cells undergo frequent division. Most anti-cancer drugs work by inserting themselves in between the DNA base pairs that encode our genetic information. This process is known as intercalation, and it can result in subtle changes to the DNA molecule’s geometric shape or tertiary structure. These structural changes interfere with the DNA’s transcription and a cell’s replication process, ultimately resulting in cell death.

While intercalating agents used in chemotherapy drugs are highly effective in fighting cancer, they also may kill important cells in the body and lead to other complications such as heart failure. Therefore, researchers are always searching for faster, cheaper and more accurate tools to aid in the design of next-generation anti-cancer drugs with reduced side effects.

A paper published in ACS Nano, one of the top nanotechnology journals in the world, explores this topic. “Modeling and Analysis of Intercalant Effects on Circular DNA Conformation,” (LINK TO http://pubs.acs.org/doi/abs/10.1021/acsnano.6b04876) focuses on the effect of the intercalating agent ethidium bromide (a mimic for many chemotherapy drugs) on the tertiary structure of DNA.

Carbon nanotube nonvolatile NRAM memory 1000 times faster than Flash will be commercially released by the end of 2018 by Nantero and Fujitsu

Nantero, Fujitsu Semiconductor and Mie Fujitsu Semiconductor today announced an agreement for Fujitsu and Mie Fujtisu to license that Nantero’s technology for NRAM, non-volatile RAM using carbon nanotubes, and to conduct joint development towards releasing a product based on 55-nm process technology.

Three companies are aiming to develop a product using NRAM non-volatile RAM that achieves several 1000 times faster rewrites and many thousands of times more rewrite cycles than embedded flash memory, making it potentially capable of replacing DRAM with non-volatile memory.

Fujitsu Semiconductor plans to develop an NRAM-embedded custom LSI product by the end of 2018, with the goal of expanding the product line-up into stand-alone NRAM product after that. Mie Fujitsu Semiconductor, which is a pure-play foundry, plans to offer NRAM-based technology to its foundry customers.

A New Way to Create Synthetic Proteins Could Lead to More Flexible Designs

Nice advancement for the nanomaterials space particularly as we look at ways to improve machines, devices, BMI, living buildings or other living structures, etc. Definitely advances efforts around Singularity.


Proteins perform a myriad of functions essential for life. They also make up important and useful biological materials, for example spider silk, which is exceptionally strong but still flexible.

The ability to design completely new proteins would help scientists create nanomaterials that, like spider silk, have a specific microstructure that confers useful properties.

Mind-controlled nanobots could be used to treat depression or epilepsy

It echoes the nanite and nanobot technology seen in science fiction TV series like Star Trek and Red Dwarf, where swarms of microscopic robots can be used to repair damaged tissue.

Researchers at Bar Ilan University in Ramat Gan, Israel, and the Interdisciplinary Centre in Herzliya, built their nanobots using a form to DNA origami to create hollow shell-like structures.

Drugs could then be placed inside these before they were chemically locked shut with particles of iron oxide.

First Direct Proof of Stable Carbyne, The World’s Strongest Material

Scientists have managed to develop a novel method to grow stable, ultra-long 1D carbon chains of a material that is twice as strong as carbon nanotubes and far stronger than diamonds.

Elemental carbon is extremely versatile, and scientists have long been able to create new carbon allotropes that make for super durable and multi-functioning materials—such as everyone’s favorite material, graphene.

The “carbon family” is one very resourceful family. But even with all these developments, carbyne remained elusive. In fact, it is the only form of carbon that has not been synthesized, even though researchers have been studying its properties for over 50 years.

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