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TruDiagnostic Discount Link (Epigenetic Testing)
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Continue reading “Epigenetic Tests #1 and 2: Horvath, Hannum, DunedinPACE” »
NIA-funded researchers identified areas of the genome responsible for accelerating or slowing down brain aging.
Including Charlie Kam, Dr. Aubrey deGrey, Valery Chuprin, Jose Cordeiro, Gennady Stolyarov, Joseph Kowalsky & Richard Daley.
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Foresight Existential Hope Group.
Program & apply to join: https://foresight.org/existential-hope/
In the Existential Hope-podcast (https://www.existentialhope.com), we invite scientists to speak about long-termism. Each month, we drop a podcast episode where we interview a visionary scientist to discuss the science and technology that can accelerate humanity towards desirable outcomes.
Continue reading “Existential Hope Special with Morgan Levine | On the Future of Aging” »
2022 https://www.cryonics.org/images/uploads/magazines/CI_NEWS-2022-02.pdfdiv.
THE CRYONICS INSTITUTE NEWSLETTER ISSUE 2, 2022 https://www.cryonics.org/images/uploads/magazines/CI_NEWS-2022-02.pdf
Circa 2016 face_with_colon_three aging reversed.
Cellular reprogramming by transient expression of Yamanaka factors ameliorates age-associated symptoms, prolongs lifespan in progeroid mice, and improves tissue homeostasis in older mice.
Talking about some of the ideas and philosophy surrounding life extension technologies. Our own psychology and coping mechanisms that view death as a good thing. The same way we used to see some diseases as a part of a gods plan. As soon as we cured these diseases, somehow they were not a part of gods plan anymore. The same will happen with aging and death, and that is just a matter of time. Picking apart some of the ways of thinking that suggest a longer life would be a boring or bad thing. We live for all of the pleasant and amazing experiences that we can have in the world, what else could possibly matter more. The end and absence of meaning (death) does not give life meaning. It is life that gives life meaning.
All around smart guy Dr Goerge Church talking about genetic engineering technologies.
George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology.
Continue reading “George Church, PhD: Rewriting Genomes to Eradicate Disease and Aging” »
Modulating Autophagy To Promote Healthspan — Dr. Ana Maria Cuervo, M.D., Ph.D., Albert Einstein College of Medicine.
Dr. Ana Maria Cuervo, M.D., Ph.D. (https://www.einsteinmed.edu/faculty/8784/ana-maria-cuervo/) is Co-Director of the Einstein Institute for Aging Research, and a member of the Einstein Liver Research Center and Cancer Center. She serves as a Professor in the Department of Developmental & Molecular Biology, and the Department of Medicine (Hepatology), and has the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases.
Aging is a complex and inevitable process that affects all organisms – and it is associated with tissue dysfunction, susceptibility to various diseases, and death [1]. The development of strategies like cellular reprogramming for increasing the duration of healthy life and promoting healthy aging is difficult since the mechanism of aging is not understood clearly. Aging is known to be associated with several hallmarks of aging – such as epigenetic alterations, genomic instability, cellular senescence, telomere shortening, mitochondrial dysfunction and altered intercellular communication.
Aging can be divided into two major phases: healthy aging and pathological aging. Healthy aging is the phase where the accumulation of minor alterations takes place, but pathological aging is the phase where clinical diseases and disabilities predominate along with the impairment of physiological functions [2].
Longevity. Technology: Notions regarding cells undergoing a unidirectional differentiation process during development existed previously [3]. However, in recent years cellular reprogramming using transcription factors has emerged as an important strategy for the rejuvenation of aging cells, erasing markers of cell damage and restoring epigenetic markers. These transcription factors also known as Yamanaka factors include Oct4, Sox2, Klf4, and c-Myc (OSKM). They can convert terminally differentiated somatic cells into pluripotent stem cells which are capable of dividing into any cell type of the body and thus can improve the health and longevity of individuals.
