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In Intel’s second “Behind this Door” video, take a sneak peek into fab D1X in Oregon to see what is likely the most complicated machine humans have built. An extreme ultraviolet (EUV) lithography system uses radically shorter wavelengths to project circuit patterns onto silicon wafers. The #EUV machine pushes Moore’s Law forward and #chip makers cannot produce leading-edge chips without it. (Credit: Intel Corporation)
#Intel #Manufacturing #Semiconductor.

▶ Learn more on Intel’s EUV: https://intel.ly/3AeAKwz.

Notice: This video contains footage provided by external vendors who have their own safety and health policies. Moreover, some footage was recorded prior to the COVID outbreak when no pandemic-related mask or social-distancing policies were needed or in place.

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Quantum researchers from CSIRO, Australia’s national science agency, have demonstrated the potential for quantum computing to significantly improve how we solve complex problems involving large datasets, highlighting the potential of using quantum in areas such as real-time traffic management, agricultural monitoring, health care, and energy optimization.

By leveraging the unique properties of quantum computing, like superposition and entanglement, researchers compressed and analyzed a large dataset with speed, accuracy, and efficiency that traditional computers cannot match.

The work is published in the journal Advanced Science.

The divide between their lineage and ours narrowed even further in 2010, when researchers published the first Neandertal genome sequence. Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then, numerous studies have explored the ways in which Neandertal DNA affects our modern physiology, revolutionizing our understanding not only of our extinct cousins but of ourselves as a hybrid species.

This area of research, clinical paleogenomics, is still in its infancy, and there are many complexities to unravel as we explore this new frontier. We therefore must take the findings from these studies with a grain of salt. Nevertheless, the research conducted to date raises the fascinating possibility that Neandertal DNA has wide-­reach­ing effects on our species—not only on general health but on brain development, including our propensity for conditions such as autism. In other words, DNA from our extinct relatives may, to some extent, shape the cognition of people today.

Synthetic Biology is on the cusp of revolutionizing biomedicine.
at NextMed Health 2023 (http://NextMedHealth.com)

Andrew Hessel is chairman of Project-write, and Author of The Genesis Machine, Our Quest to Rewrite Life in the Age of Synthetic Biology.

More about Andrew Hessel: https://www.nextmed.health/bio-andrewhessel.

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Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during reproduction. The map marks a major step in the understanding of genetic diversity and its impact on health and fertility. It continues 25 years of research at deCODE genetics into how new diversity is generated in the human genome, and its relationship to health and disease.

The new map, appearing today in the online edition of Nature, is the first to incorporate shorter-scale shuffling, (non crossover) of grandparental DNA, which is difficult to detect due to the high DNA sequence similarity. The map also identifies areas of DNA that are devoid of major reshuffling, likely to protect critical genetic functions or prevent chromosomal problems. This insight offers a clearer picture of why some pregnancies fail and how the genome balances diversity with stability.

While this shuffling, known as , is essential for genetic diversity, errors in the process can lead to serious reproductive issues. These failures can result in genetic errors that prevent pregnancies from continuing, helping to explain why infertility affects around one in ten couples worldwide. Understanding this process offers new hope for improving fertility treatments and diagnosing pregnancy complications.

Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win. At first, a brain chemical called dopamine is essential for young males to master this behavior. But as they gain experience, the chemical grows less important in promoting aggression, a new study shows.

Dopamine has been linked to male aggression for decades. How past experiences might influence this relationship, however, had until now been unclear.

In experiments in rodents, a team led by researchers at NYU Langone Health boosted activity in -releasing cells in a part of the brain called the . The findings revealed that in inexperienced male fighters, this led the animals to attack for twice as long as they would have fought naturally. When the cells were blocked, the novice mice would not fight at all.

The ability to regulate one’s own food intake is essential to the survival of both humans and other animals. This innate ability ensures that the body receives the nutrients it needs to perform daily activities, without significantly exceeding calorie intake, which could lead to health problems and metabolic disorders.

Past neuroscience studies suggest that the regulation of food intake is supported by specific regions in the brain, including the hypothalamus and caudal nucleus of the solitary tract (cNTS), which is part of the brainstem. This key region in the brainstem is known to integrate originating from the gut and then transform them into adaptive feeding behaviors.

While previous research has highlighted the key role of the cNTS in food intake regulation, the unique contribution of the different neuron subtypes within this brainstem region and the mechanisms by which they regulate feeding remain poorly understood. Better understanding these neuron-specific mechanisms could help to devise more effective therapeutic interventions for obesity and eating disorders.

Past research suggests that meditation and exposure to art or nature can positively impact people’s well-being and brain health, in some cases even reducing stress and supporting the processing of emotions. Yet most past studies focused on each of these experiences individually, rather than comparing their effects on brain activity.

Researchers at University of California Los Angeles set out to examine the brain activation patterns associated with a visualization-based of connecting to the cosmic soul and compare them to those from people watching evocative digital art or nature videos.

Their findings, published in Frontiers in Human Neuroscience, suggest that these different types of transcending experiences prompt different brain activation patterns.