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Freedom of Information Act requests are rarely speedy, but when a group of scientists asked the federal government to share the data it relied upon in licensing Pfizer’s COVID-19 vaccine, the response went beyond typical bureaucratic foot-dragging.

55 years and longer.

That’s how long the Food & Drug Administration in court papers this week proposes it should be given to review and release the trove of vaccine-related documents responsive to the request. If a federal judge in Texas agrees, plaintiffs Public Health and Medical Professionals for Transparency can expect to see the full record in 2076.

Fundamental Research On Ethical & Trustworthy Artificial Intelligence, For Health, Environment, And A Sustainable Future — Dr. Patrick van der Smagt, Ph.D., Director, ArtificiaI Intelligence Research, Volkswagen.


Dr. Patrick van der Smagt is Director of ArtificiaI Intelligence Research, Volkswagen AG, and Head of Argmax. AI (https://argmax.ai/), the Volkswagen Group Machine Learning Research Lab, in Munich, focusing on a range of research domains, including probabilistic deep learning for time series modelling, optimal control, reinforcement learning robotics, and quantum machine learning.

Dr. van der Smagt is also a research professor in the Computer Science faculty at Eötvös Loránd University in Budapest.

The creation of nanoscale computers for use in precision health care has long been a dream of many scientists and health care providers. Now, for the first time, researchers at Penn State have produced a nanocomputing agent that can control the function of a particular protein that is involved in cell movement and cancer metastasis. The research paves the way for the construction of complex nanoscale computers for the prevention and treatment of cancer and other diseases.

Nikolay Dokholyan, G. Thomas Passananti Professor, Penn State College of Medicine, and his colleagues — including Yashavantha Vishweshwaraiah, postdoctoral scholar in pharmacology, Penn State — created a transistor-like ‘logic gate,’ which is a type of computational operation in which multiple inputs control an output.

“Our logic gate is just the beginning of what you could call cellular computing,” he said, “but it is a major milestone because it demonstrates the ability to embed conditional operations in a protein and control its function, said Dokholyan. ” It will allow us to gain a deeper understanding of human biology and disease and introduces possibilities for the development of precision therapeutics.”

The era of space exploration brings with it a new risk: invasion. The peril comes not from little green men arriving on flying saucers but, rather, from microbiological contamination of Earth from extraterrestrial environments and vice versa. Writing in BioScience, Anthony Ricciardi, of McGill University, and colleagues describe the dangers posed by such organisms and outline an approach to address the threat.

The authors caution that biological contamination endangers both ecosystems and human well-being. “Owing to their massive costs to resource sectors and human health, biological invasions are a global biosecurity issue requiring rigorous transboundary solutions,” say Ricciardi and colleagues. And that threat may be more immediate than previously anticipated. Despite considerable microbial caution among space agencies, say the authors, “bacterial strains exhibiting extreme resistance to ionizing radiation, desiccation, and disinfectants have been isolated in NASA

Established in 1958, the National Aeronautics and Space Administration (NASA) is an independent agency of the United States Federal Government that succeeded the National Advisory Committee for Aeronautics (NACA). It is responsible for the civilian space program, as well as aeronautics and aerospace research. It’s vision is To discover and expand knowledge for the benefit of humanity.

Creating a world where no woman has to die giving life — temitayo erogbogbo, global advocacy director, MSD for mothers, merck sharp & dohme.


Mr. Temitayo (Tayo) Erogbogbo, is Global Advocacy Director of MSD for Mothers (https://www.msdformothers.com/), at Merck Sharp & Dohme.

Tayo has two decades of combined private sector and international development experience, 13 years of which was spent in the pharmaceutical industry in multiple roles across community relations, government affairs, marketing and sales.

It’s more likely than you think.


When it comes to interstellar missions, however, there are no plans for crewed missions on the table. While there are proposals for sending robotic missions, sending astronauts to nearby stars and exoplanets simply isn’t feasible yet.

However, according to new research led by the University of California, interstellar missions could be conducted in the near future that would have tardigrades (aka. “Water Bears”) as their crew.

Pfizer has pledged a shipment of its experimental antiviral COVID-19 pill to Israel, according to a Saturday television report, a week after the US drugmaker said it was engaged in “active discussion” with 90 countries regarding the coronavirus medication.

Prime Minister Naftali Bennett and Health Minister Nitzan Horowitz reached an agreement with the drug company for tens of thousands of doses, Channel 12 news reported. The shipment will be despatched as soon as Pfizer receives FDA approval for the pill, the TV report said.


PM and health minister reach agreement with drug company for ‘tens of thousands of doses’; initial data shows almost 90% efficacy.

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Papers referenced in the video:
Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a.
https://pubmed.ncbi.nlm.nih.gov/34725961/

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double-blind, placebo-controlled, multicenter trial: The MASTERS trial.
https://pubmed.ncbi.nlm.nih.gov/31557380/

Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults.

Forget all the nanotechnology devoted to fighting cancer, and just consider that nanoparticles have invaded makeup, anti-odor socks, sunscreen, plastic beer bottles and home pregnancy tests. Now scientists have developed a way to assess the health and environmental impact of such nanoparticles: a tiny microresonator that can detect and measure individual particles smaller than a single virus.

The microresonator is a lab-on-a-chip that harnesses the “whispering gallery” concept that’s displayed by buildings such as St. Paul’s Cathedral in London. The cathedral’s domed gallery can carry whispers easily across to the other side, but normal-volume voices end up garbled after bouncing around the dome multiple times.

Similarly, microresonators can bounce laser light many times around a circular “waveguide,” such as a glass ring. A laser frequency must perfectly fit the circumference of a ring to achieve this whispering-gallery mode.