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Category: health – Page 151

Ambassador Dr. John-Arne Røttingen, MD, Ph.D. (https://www.bsg.ox.ac.uk/people/john-arne-rottingen) is Ambassador for Global Health, at the Ministry of Foreign Affairs, Norway, and a Visiting Fellow of Practice, at the Blavatnik School of Government, Oxford University.

Ambassador Dr. Røttingen has previously served as the Chief Executive of the Research Council of Norway; the founding Chief Executive Officer of the Coalition for Epidemic Preparedness Innovations (CEPI); Executive Director of Infection Control and Environmental Health at the Norwegian Institute of Public Health; founding Chief Executive of the Norwegian Knowledge Centre for the Health Services; Professor of Health Policy at the Department of Health Management and Health Economics, Institute of Health and Society, University of Oslo; and Adjunct Professor at the Department of Global Health and Population, Harvard T.H. Chan School of Public Health.

From 2020, Ambassador Dr. Røttingen also chaired the Executive Group and the International Steering Committee of the WHO Solidarity trial to compare four untested treatments for hospitalized people with severe COVID-19 illness. In early 2021, he was appointed by the G20 to the High Level Independent Panel (HLIP) on financing the global commons for pandemic preparedness and response. That same year, he was also appointed to the Pandemic Preparedness Partnership (PPP), an expert group chaired to advise the G7 presidency. From mid-2021, he was part of the Access to COVID-19 Tools Accelerator’s Vaccine Manufacturing Working Group.

Ambassador Dr. Røttingen received his MD and Ph.D. from the University of Oslo, an MSc from Oxford University and an MPA from Harvard University.

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In the intensive care unit (ICU), critically ill patients are cared for by a multidisciplinary care team. Compassionate and caring behaviors on the part of the care team result in better outcomes for patients and their families, and care providers entering the demanding field of medicine because they wish to help people and relieve suffering. However, studies have demonstrated deficiencies in delivering compassionate health care. Evidence suggests that physicians may miss up to 90% of opportunities to respond to patients with compassion.

To determine what factors drive and enhance compassionate care behaviors in the ICU setting and which factors drain and negate caring attitudes and behaviors, Shahla Siddiqui, MD, MSc, FCCM, and a colleague conducted an observational, qualitative study of an international panel of intensive and critical . The researcher-clinicians report in PLOS ONE that while ICU physicians and nurses feel a deep moral imperative to deliver the highest level of compassionate care, pressures of capacity strain, lack of staff, lack of compassionate skills training and a heavy emphasis on electronic health record maintenance present significant hurdles to achieving that goal.

“Studies done on physician compassion from a patient perspective emphasize listening and awareness of the patient’s , which not only builds trust within the patient-physician relationship but also enhances resilience amongst the care team and prevents burnout,” said Siddiqui, an anesthesiologist at BIDMC. “Our aim was to describe compassionate behaviors in the ICU, study the factors that enhance and those that drain such behaviors with an aim to enable recommendations for practice and training.”

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“Introducing the first soft material that can maintain a high enough electrical conductivity to support power hungry devices.” and self-healing.

The newest development in softbotics will have a transformative impact on robotics, electronics, and medicine. Carmel Majidi has engineered a soft material with metal-like conductivity and self-healing properties that, for the first time, can support power-hungry devices.

“Softbotics is about seamlessly integrating robotics into everyday life, putting humans at the center,” explained Majidi, a professor of mechanical engineering.

Engineers work to integrate robots into our everyday lives with the hope of improving our mobility, health, and well-being. For example, patients might one day recover from surgery at home thanks to a wearable robot monitoring aid. To integrate robots seamlessly, they need to be able to move with us, withstand damage, and have electrical functionality without being encased in a hard structure.

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Your circadian rhythm doesn’t just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review paper published in the journal Trends in Cell Biology, researchers discuss the role of circadian rhythms in tumor progression and spread and describe how we could better time when patients are tested for cancer and when they receive therapies to improve diagnostic accuracy and improve treatment success.

“The circadian rhythm governs most of the cellular functions implicated in cancer progression, and therefore its exploitation opens new promising directions in the fight against metastasis,” write the authors, molecular oncologists Zoi Diamantopoulou, Ana Gvozdenovic, and Nicola Aceto from the ETH Zurich in Switzerland.

Our circadian rhythms help our bodies synchronize different tasks throughout the day, including gene expression, immune function, and cell repair. We’ve long known that chronically disrupted circadian rhythms—as a result of erratic sleep patterns, jet lag, or , for example—can predispose us to a number of health issues, including cancer. More recent work has shown that circadian rhythms are not only involved in tumor onset, but also govern and metastasis, the colonization of secondary sites within the body.

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Researchers from the University of Geneva (UNIGE), the Geneva University Hospitals (HUG), and the National University of Singapore (NUS) have developed a novel method for evaluating the interpretability of artificial intelligence (AI) technologies, opening the door to greater transparency and trust in AI-driven diagnostic and predictive tools. The innovative approach sheds light on the opaque workings of so-called “black box” AI algorithms, helping users understand what influences the results produced by AI and whether the results can be trusted.

This is especially important in situations that have significant impacts on the health and lives of people, such as using AI in . The research carries particular relevance in the context of the forthcoming European Union Artificial Intelligence Act which aims to regulate the development and use of AI within the EU. The findings have recently been published in the journal Nature Machine Intelligence.

Time series data—representing the evolution of information over time—is everywhere: for example in medicine, when recording heart activity with an electrocardiogram (ECG); in the study of earthquakes; tracking weather patterns; or in economics to monitor financial markets. This data can be modeled by AI technologies to build diagnostic or predictive tools.

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More magnesium in our daily diet leads to better brain health as we age, according to scientists from the Neuroimaging and Brain Lab at The Australian National University (ANU).

The researchers say increased intake of -rich foods such as spinach and nuts could also help reduce the risk of dementia, which is the second leading cause of death in Australia and the seventh biggest killer globally.

The study of more than 6,000 cognitively healthy participants in the United Kingdom aged 40 to 73 found people who consume more than 550 milligrams of magnesium each day have a brain age that is approximately one year younger by the time they reach 55 compared with someone with a normal magnesium intake of about 350 milligrams a day.

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Researchers in the Oregon State University College of Engineering have developed a handheld sensor that tests perspiration for cortisol and provides results in eight minutes, a key advance in monitoring a hormone whose levels are a marker for many illnesses including various cancers.

Findings were published in the journal ACS Applied Materials & Interfaces. The material and sensing mechanism in the new device could be easily engineered to detect other specific hormones, the researchers say—for example, progesterone, a key marker for women’s reproductive health and pregnancy outcomes.

“We took inspiration from the natural enzymes used in sold at pharmacies,” said Larry Cheng, associate professor of electrical engineering and computer science. “In glucose meters, specific enzymes are applied to an electrode, where they can capture and react with glucose molecules to generate an electrical signal for detection. However, finding natural enzymes for cortisol detection is not straightforward, and natural enzymes are prone to instability and have a short lifespan.”

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Physicists at Delft University of Technology have built a new technology on a microchip by combining two Nobel Prize-winning techniques for the first time. This microchip could measure distances in materials at high precision—for example, underwater or for medical imaging.

Because the technology uses sound vibrations instead of light, it is useful for high-precision position measurements in opaque materials. The instrument could lead to new techniques to monitor the Earth’s climate and human health. The work is now published in Nature Communications.

The microchip mainly consists of a thin ceramic sheet that is shaped like a trampoline. This trampoline is patterned with holes to enhance its interaction with lasers and has a thickness about 1,000 times smaller than the thickness of a hair. As a former Ph.D. candidate in Richard Norte’s lab, Matthijs de Jong studied the small trampolines to figure out what would happen if they pointed a simple at them.

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Studying Our Ocean’s History To Understanding Its Future — Dr. Emily Osborne, PhD, Ocean Chemistry & Ecosystems Division, National Oceanic and Atmospheric Administration (NOAA)

Dr Emily Osborne, Ph.D. (https://www.aoml.noaa.gov/people/emily-osborne/) is a Research Scientist, in the Ocean Chemistry and Ecosystems Division, at the Atlantic Oceanographic and Meteorological Laboratory.

The Atlantic Oceanographic and Meteorological Laboratory (AOML), a federal research laboratory, is part of the National Oceanic and Atmospheric Administration’s (NOAA) Office of Oceanic and Atmospheric Research (OAR), located in Miami in the United States. AOML’s research spans tropical cyclone and hurricanes, coastal ecosystems, oceans and human health, climate studies, global carbon systems, and ocean observations. It is one of ten NOAA Research Laboratories.

With a B.S. in Geology from the College of Charleston and a Ph.D. in Marine Science from University of South Carolina, Dr. Osborne is currently involved in investigating regional and global biogeochemical issues related to ocean health and climate through the use of a combination of paleoceanographic approaches, new autonomous sensors, and conventional measurements on large multi-disciplinary oceanographic cruises.

Paleoceanography is the study of the history of the oceans in the geologic past with regard to circulation, chemistry, biology, geology and patterns of sedimentation and biological productivity. Paleoceanographic studies using environment models and different proxies enable the scientific community to assess the role of the oceanic processes in the global climate by the re-construction of past climate at various intervals.

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