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Category: health – Page 133

Dedicated to ending the HIV epidemic — dr. moupali das, MD, MPH, executive director, HIV clinical research, gilead sciences.

Dr. Moupali Das, MD, MPH, is Executive Director, HIV Clinical Research, in the Virology Therapeutic Area, at Gilead Sciences (https://www.gilead.com/), where she leads the pre-exposure prophylaxis (PrEP) clinical drug development program, including evaluating the safety and efficacy of a long-acting, twice yearly, subcutaneous injection being studied for HIV prevention. Her responsibilities also include expanding the populations who may benefit from PrEP.

Dr. Das has led high-performing teams in academic medicine, public health, implementation science, and cross-functionally in drug development. She has successfully helped develop, implement, and evaluate how to better test, link to care, increase virologic suppression, and improve quality of life for people with HIV, and to prevent HIV in those who may benefit from PrEP.

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The soot produced by unburnt hydrocarbon flames is the second largest contributor to global warming, while also harming human health. Researchers have developed state-of-the-art, high-speed imaging techniques to study turbulent flames, yet they are limited to an imaging rate of million-frames-per-second. Physicists are therefore keen to obtain a complete picture of flame-laser interactions via single-pulse imaging.

In a new report published in Light: Science & Applications, Yogeshwar Nath Mishra and a research team at the Caltech Optical Imaging Laboratory, the NASA Jet propulsion lab, department of physics, and the Institute of Engineering Thermodynamics in the U.S., and Germany, used single-shot laser-sheet comprised ultrafast photography per billion frames per second, for the first time, to observe the dynamics of laser-flames.

The team noted laser-induced incandescence, elastic light scattering and the fluorescence of soot precursors such as polycyclic aromatic hydrocarbons in , with a single nanosecond laser pulse. The research outcomes provide strong experimental evidence to support soot inception and growth mechanisms in flames. Mishra and the team combined a variety of techniques to probe the short-lived species in turbulent environments to unravel the mysteries of hot plasma, nuclear fusion and sonoluminescence.

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Rational Virology Research For Human Health & Pandemic Prevention — Dr. Felicia Goodrum Sterling, Ph.D. Professor, Department of Immunobiology, The University of Arizona.

Dr. Felicia Goodrum, Ph.D. (https://profiles.arizona.edu/person/fgoodrum) is Interim Associate Department Head and Professor of Immunobiology, as well as Professor, BIO5 Institute, Cellular and Molecular Medicine, Molecular and Cellular Biology, Cancer Biology And Genetics Graduate Interdisciplinary Programs, at the University of Arizona.

Dr. Goodrum earned her Ph.D. from Wake Forest University School of Medicine studying cell cycle restrictions to adenovirus replication and then trained as a postdoctoral fellow at Princeton University in the laboratory of Dr. Thomas Shenk studying human cytomegalovirus latency.

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The man may have acquired this very rare infection after rinsing his sinuses with tap water, the Florida Department of Health in Charlotte County said in a news release.

While health officials continue to investigate the cause of the Naegleria fowleri infection, they emphasized that it can’t be contracted from drinking tap water.

These infections only happen when contaminated water enters through the sinuses, officials said.

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Poor sleep could lead to between two and seven years worth of heightened heart disease risk and even premature death, according to a new study led by researchers at the University of Sydney in collaboration with Southern Denmark University.

The study analyzed data from more than 300,000 middle-aged adults from the UK Biobank and found that different disturbances to sleep are associated with different durations of compromised later in life compared to healthy sleepers.

In particular, men with clinical sleep-related breathing disorders lost nearly seven years of cardiovascular disease-free life compared to those without these conditions, and women lost over seven years. Importantly, even general , such as insufficient sleep, insomnia complaints, snoring, going to bed late, and is associated with a loss of around two years of normal heart health in men and women.

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A team of researchers from Michigan State University’s College of Veterinary Medicine has made a discovery that may have implications for therapeutic gene editing strategies, cancer diagnostics and therapies and other advancements in biotechnology.

Kathy Meek, a professor in the College of Veterinary Medicine, and collaborators at Cambridge University and the National Institutes of Health have uncovered a previously unknown aspect of how DNA double-stranded breaks are repaired.

A large protein kinase called DNA-PK starts the DNA repair process; in their new report, two distinct DNA-PK protein complexes are characterized, each of which has a specific role in DNA repair that cannot be assumed by the other.

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