Lifeboat Foundation

Scientists have discovered that an inflammatory cytokine known as LIGHT is a major factor in the deadly airway damage that can affect people with severe asthma. This research has suggested that such airway damage could be reversed by therapeutics that halt LIGHT, and the molecule could offer a way to treat asthma. The study, which used a mouse model and human tissue, has been reported in the Journal of Allergy and Clinical Immunology.

“This is a very, very significant finding,” said senior study author and LJI Professor Michael Croft, Ph.D. “This research gives us a better understanding of the potential of therapeutic targeting of LIGHT and what we might do to relieve some of the symptoms and some of the inflammatory features seen in patients who have severe asthma.”

The secret to great health is within our control, based on 23 drivers that are largely modifiable.

Immunotherapy is a type of drug that might be an option if you have triple-negative breast cancer.

Triple-negative breast cancer, also called basal-like breast cancer, is not sensitive to hormones. This means that the breast cancer cells don’t use estrogen or progesterone to grow and they don’t have hormone receptors. This type of breast cancer also doesn’t produce too much of the growth-promoting protein called HER2.

“Triple-negative breast cancer is about 10% to 15% of all breast cancer cases,” says Pooja Advani, M.D., a medical oncologist with the Robert and Monica Jacoby Center for Breast Health at Mayo Clinic in Florida.

Cells with XX or XY chromosomes provide researchers with a new tool to study how differences in sex chromosomes can influence health and development.

Professor Carmit Levy. Credit: Tel Aviv University.

Professor Carmit Levy from the Department of Human Genetics and Biochemistry and Dr. Yftach Gepner from the School of Public Health and the Sylvan Adams Sports Institute at TAU’s Sackler Faculty of Medicine conducted the study. Prof. Levy notes that the new research has resulted in a very important discovery by merging scientific know-how from different schools at TAU, which may help avoid metastatic cancer, Israel’s top cause of death. The study was recently published on the cover of the journal of Cancer Research.

Prof. Levy and Dr. Gepner: “Studies have demonstrated that physical exercise reduces the risk for some types of cancer by up to 35%. This positive effect is similar to the impact of exercise on other conditions, such as heart disease and diabetes. In this study we added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been ‘be active, be healthy’, now we can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer.”

We all lead busy lives, and it can be hard to remember to eat healthy. Sometimes, it’s easier to just grab food off the shelf, thinking only of the convenience and not of the nutritional value. Processed foods are always on-hand, and they’ve saved us time and energy in the past. But, at what cost?

Many of the products on this list are staples of our daily diet. However, if not eaten in strict moderation (or avoided completely) they can lead to long-term health problems. Some of these products are clearly harmful, but others seem like healthy foods, only to be proven unhealthy when it’s too late. After looking at this list, you might want to reconsider what you put on your shopping list.

In this episode, Emad and Peter discuss everything from AI-generated content and property rights to ethical implications, along with the upcoming hyper-disruption wave of technology in all industries.

Emad Mostaque is the CEO and Co-Founder of Stability AI, a company funding the development of open-source music-and image-generating systems such as Dance Diffusion and Stable Diffusion.

Continue reading “AI Will Be a Public Good With Emad Mostaque | EP #16 Moonshots and Mindsets” »

For those curious about the Ukraine war which is involving over 75 countries (and the number keeps growing!):

Ukraine has received 41 powerful generators intended for health facilities from the Republic of Kazakhstan. Kazakhstan was occupied by Russian troops earlier this year so this is a big deal. Russia also does all their space launches from Kazakhstan.

The relevant statement was made by the Ukrainian Health Ministry on Facebook, an Ukrinform correspondent reports.

Continue reading “Ukraine receives 41 hospital generators from Kazakhstan” »

Astronauts are at higher risk for developing mutations—possibly linked to spaceflight—that can increase the risk of developing cancer and heart disease during their lifetimes, according to a first-of-its kind study from the Icahn School of Medicine at Mount Sinai.

Mount Sinai study could lead to ongoing health monitoring of astronauts to assess possible health risks and prevent disease progression.