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PI3K/AKT signaling mediates stress-inducible amyloid formation through c-Myc

Lacroix et al. demonstrate that heat-induced activation of the PI3K/AKT signaling cascade drives the formation of functional amyloid aggregates that protect cells from harsh environmental conditions. Here, activation of PI3K and AKT represses GSK3-mediated degradation of c-Myc, leading to upregulation of nucleating noncoding RNAs that mediate this physiological amyloidogenic event.

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5 Weird Civilisations Sci-Fi Books You Need to Read

Today we’re taking a tour through some of the weirdest civilisations in science fiction.

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0:00 — intro.
0:48 — Eden by Stanisław Lem.
2:36 — The Child Garden by Geoff Ryman.
4:17 — The Mote in God’s Eye by Larry Niven & Jerry Pournelle.
5:50 — The Gods Themselves by Isaac Asimov.
7:27 — Honourable Mentions:
Embassytown by China Miéville.
City by Clifford D. Simak.
Engine Summer by John Crowley.
9:44 — A Deepness in the Sky by Vernor Vinge.

#scifi #weird #books.

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DELPHINE DESCENDS 📖 — (Amazon link) https://shortlink.uk/P59l.

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