Codenamed GT1, the electric sedan will offer up to 603 hp and over 400 miles of range, according to a leaked production schedule. But will anybody buy it?
Category: futurism – Page 298
Shedding Light on Cell Attachment
“Focus has been on how cells become mechanosensitive, how cell adhesion became mechanosensitive through the recruitment of mechanosensitive proteins like talin, vinculin, and also other proteins,” said Sangyoon Han, a mechanobiologist at Michigan Technological University who was not involved in the study. “But not many studies were around to tell if there is any kind of premechanosensitive processes that act as a seed for the original binding of this mechanosensitive binding.”
Cooper’s team imaged adhesion formation at the cell surface interface using total internal reflection (TIRF) microscopy and observed that activated Cas clustered at this site almost a full minute before mechanosensing proteins arrived or β1 integrin was activated. They depleted Cas with siRNA and inactivated it to determine this protein’s role in the developing adhesion site. “When we remove Cas from cells, or inhibit its phosphorylation, or inhibit stuff downstream of Cas, the integrin clustering doesn’t really happen,” Cooper said. The Cas-depleted cells attached poorly to surfaces and were immobile.
Finally, the group identified a positive feedback loop between Cas and Rac1, which drives actin polymerization and is important in forming focal complexes that promoted cell adhesion formation.5,6 Cas phosphorylation activated Rac1, which in turn generated reactive oxygen species, which promoted additional Cas activation. Cas degradation regulated this loop.
It’s a Tremendous Shock When You Discover This — J. Krishnamurti & David Bohm | Black Screen
00:00 start16:49 why reject organized religion35:22 ‘the centre’ is an illusion39:12 no relationship between me and truth49:27 it’s absolutely worthless53:20…
Zuckerberg slams Apple Vision Pro, says Quest 3 is better in every way
Apple’s Vision Pro may have dazzled the world with its stunning display and sleek design, but not everyone is convinced it’s the best headset on the market. One of its biggest rivals, Meta CEO Mark Zuckerberg, has some pinching words for the device and its maker.
So why is Quest 3 a better overall product according to Zuck?
Zuckerberg took to Instagram on Tuesday to share his thoughts on the Vision Pro, which he tried out for himself. He compared it to Meta’s Quest 3, the latest version of the popular standalone VR headset. He filmed the video using the Quest 3’s video passthrough feature, which lets users see the real world in color through the headset’s cameras.
ChatGPT: Everything you need to know about the AI chatbot
You’ll soon be able to tell ChatGPT to forget things — or remember specific things in future conversations.
Here’s a ChatGPT guide to help understand Open AI’s viral text-generating system. We outline the most recent updates and answer your FAQs.
Unlocking the Cosmos: The SETI Ellipsoid Approach to Technosignature Detection
“New surveys of the sky provide groundbreaking opportunities to search for technosignatures coordinated with supernovae.” said Bárbara Cabrales.
Are we alone in the universe? This longstanding question is what the SETI (Search for Extraterrestrial Intelligence) Institute has been trying to answer for decades as its vast array of radio telescopes continues to scan the heavens for signs of intelligent life beyond Earth, also known as technsigatures. Now, a team of researchers led by the Berkeley SETI Research Center have developed the SETI Ellipsoid with the hope it will offer greater opportunities for identifying technsigatures from intelligent civilizations throughout the cosmos. These findings were recently published in The Astronomical Journal and hold the potential to help scientists better understand the necessary criterion for finding intelligent life beyond Earth.
For the study, the researchers began by hypothesizing that intelligent civilizations could use what’s known as a Schelling point (more commonly called a focal point) during supernovae events as an opportunity to broadcast coordinated signals announcing their existence to the cosmos. The researchers then compared this criterion to data from NASA’s TESS (Transiting Exoplanet Survey Satellite) spacecraft, finding the criterion matched 5 percent of TESS data. After searching through the data using their new SETI Ellipsoid method, the team identified zero technosignatures, but noted this new method could provide unique opportunities for identifying technosignatures in the future.
Animation of the SETI ellipsoid with Earth at the far right and a potential technosignature civilization at the upper left. (Credit: Zayna Sheikh)