Lifeboat Foundation

Previous research published earlier this year in Nature Medicine involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer and Mayo Clinic investigators James L. Kirkland and Tamara Tchkonia, showed it was possible to reduce the burden of damaged cells, termed senescent cells, and extend lifespan and improve health, even when treatment was initiated late in life. They now have shown that treatment of aged mice with the natural product Fisetin, found in many fruits and vegetables, also has significant positive effects on health and lifespan.

As people age, they accumulate damaged cells. When the cells get to a certain level of damage they go through an aging process of their own, called cellular senescence. The cells also release inflammatory factors that tell the immune system to clear those damaged cells. A younger person’s immune system is healthy and is able to clear the damaged cells. But as people age, they aren’t cleared as effectively. Thus they begin to accumulate, cause low level inflammation and release enzymes that can degrade the tissue.

Robbins and fellow researchers found a natural product, called Fisetin, reduces the level of these damaged cells in the body. They found this by treating mice towards the end of life with this compound and see improvement in health and lifespan. The paper, “Fisetin is a senotherapeutic that extends health and lifespan,” was recently published in EBioMedicine.

A new tool using data and AI is hoping to better predict famine and help millions experiencing food insecurity.

Is it time for cosy agricultural era universtites to be seriously disrupted with physical campuses abolished in this modern age when we are all Professor Googles, and when knowledge evolves faster than courses? Why pay rip off fees for information that is out of date before the end of three years?

Senior professors among 300 people alleged to have bullied students and colleagues.

Scientists and dietitians are starting to agree on a recipe for a long, healthy life. It’s not sexy, and it doesn’t involve fancy pills or pricey diet potions.

Fill your plate with plants. Include vegetables, whole grains, healthy fats, and legumes. Don’t include a lot of meat, milk, or highly processed foods that a gardener or farmer wouldn’t recognize.

“There’s absolutely nothing more important for our health than what we eat each and every day,” Sara Seidelmann, a cardiologist and nutrition researcher at Brigham and Women’s Hospital in Boston, told Business Insider.

Continue reading “This Study on Nearly Half a Million People Has Bad News For The Keto Diet” »

Is this good as space food?

The latest entree to join the Army’s roster of M.R.E. field rations is a Sicilian-style slice that stays fresh for years and took decades to develop.

When the California two-spot octopus isn’t attempting to bring more eight-legged cephalopods into this world, it prefers to be alone. Known to scientists as Octopus bimaculoides, the alien-like invertebrate spends most of its time hiding from the world or searching for food, asocial males avoiding asocial females until their biological clocks say it’s time to partner up. That is, until they are on MDMA. In a groundbreaking study released Thursday, researchers describe how octopuses on the drug act similarly to a socially anxious human on MDMA: They open up.

Gül Dölen, Ph.D., is an assistant professor of neuroscience at Johns Hopkins University and the co-author of the new Current Biology paper. She tells Inverse that when octopuses are on MDMA, it’s like watching “an eight-armed hug.”

“They were very loose,” Dölen says. “They just embraced with multiple arms.”

Waste has become a serious problem in Western societies. About a third of the food produced in countries such as the [United Kingdom](http://foodawarecic.org.uk/stats-2/](http://foodawarecic.org.uk/stats-2/), Australia and the United States is wasted. About 40% is wasted by consumers, who buy too much, forget what’s in their refrigerator or cupboards, or throw away food that is past its expiration date yet perfectly edible.

Immense amounts of food is discarded by stores or restaurants because they weren’t sold before the official selling date, or for esthetic reasons – vegetables or fruit that have unusual shapes or are too big or too small, or food packages that are distorted… Waste also occurs with electronic goods that are discarded even though they work just fine and millions of tons of usable paper that are thrown away every year.

I don’t remember what it feels like to live without pain. At 15, I began feeling aching, stabbing, and burning sensations in my lower back and down my legs. Swallowing a few Aleve didn’t help—in fact, nothing did. If I sit or stand for any period of time, or lift something heavy or fall, I pay for it, sometimes for weeks or months. I’ve slept on the kitchen linoleum, because the carpet felt too soft to stand.

For 17 years, I went to doctor after doctor, undergoing scans, physical therapy, and just about every “alternative” treatment that promised relief. Despite some amazing doctors and the expensive tests at their disposal, they could never see anything wrong, so I never got a diagnosis.

That is, until a couple of years ago, when a routine CAT scan finally caught a structural problem with my spine. Because of that, I qualified to have a spinal cord stimulator, an electronic device used to treat chronic pain, implanted into my back. Although I was scared to go under the knife, I was more than willing to become a cyborg in order to find even partial relief. And this type of therapy might also be able to help some of the 100 million Americans who suffer from chronic pain.

A new research discovered the mechanism behind the positive effect of consuming food rich in unsaturated fats. The role of the plasma protein- Apolipo IV as an inhibitor of aggregation of platelets for the diminishing occurrence of heart attack, stroke, atherosclerosis was established.

Foods high in unsaturated fats may protect against cardiovascular disease, and new research published today in Nature Communications has uncovered why.

Apolipoprotein A-IV, known as ApoA-IV, is a plasma protein. Levels of ApoA-IV increase after the digestion of foods, particularly foods high in unsaturated fats, such as olive oil. Higher levels of ApoA-IV in the blood have been reported to be associated with lower rates of cardiovascular disease.

Continue reading “How olive oil and sleep could stave off heart attacks and strokes—new study examines plasma protein’s role” »