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Dramatic expansion of the human cerebral cortex, over the course of evolution, accommodated new areas for specialized cognitive function, including language. Understanding the genetic mechanisms underlying these changes, however, remains a challenge to neuroscientists.

A team of researchers in Japan has now elucidated the mechanisms of cortical evolution. They used molecular techniques to compare the in mouse and monkey brains.

Using the technique called in situ hybridization to visualize the distribution of mRNA transcripts, Okano, Shimogori and their colleagues examined the expression patterns of genes that are known to regulate development of the . They compared these patterns to those of the same genes in the brain of the common marmoset. They found that most of the genes had similar expression patterns in mice and marmosets, but that some had strikingly different patterns between the two species. Notably, some areas of the visual and prefrontal showed expression patterns that were unique to marmosets.

A new UC Davis-led study sheds light on cell type-specific biomarkers, or signs, of melanoma. The research was recently published in the Journal of Investigative Dermatology.

Melanoma, the deadliest of the common skin cancers, is curable with and treatment. However, diagnosing clinically and under the microscope can be complicated by what are called melanocytic nevi—otherwise known as birth marks or moles that are non-cancerous. The development of melanoma is a multi-step process where “melanocytes,” or the cells in the skin that contain melanin, mutate and proliferate. Properly identifying melanoma at an early stage is critical for improved survival.

“The biomarkers of early melanoma evolution and their origin within the tumor and its microenvironment are a potential key to early diagnosis of melanoma,” said corresponding author of the study Maija Kiuru, associate professor of clinical dermatology and pathology at UC Davis Health. “To unravel the mystery, we used high-plex spatial RNA profiling to capture distinct gene expression patterns across cell types during melanoma development. This approach allows studying the expression of hundreds or thousands of genes without disrupting the native architecture of the tumor.”

The motion of a tiny number of charged particles may solve a longstanding mystery about thin gas disks rotating around young stars, according to a new study from Caltech.

These features, called , last tens of millions of years and are an early phase of solar system evolution. They contain a small fraction of the mass of the star around which they swirl; imagine a Saturn-like ring as big as the solar system. They are called accretion disks because the gas in these disks spirals slowly inward toward the star.

Scientists realized long ago that when this inward spiraling occurs, it should cause the radially inner part of the disk to spin faster, according to the law of the conservation of angular momentum. To understand conservation of angular momentum, think of spinning figure skaters: when their arms are outstretched, they spin slowly, but as they draw their arms in, they spin faster.

NLM’s NCBI is introducing the Comparative Genome Viewer (CGV), an easy-to-use visualization tool that helps you quickly compare eukaryotic genome assemblies and easily identify genomic changes that may be significant to biology and evolution. With the new CGV you can view and compare the alignment between two assemblies to see differences in genomic sequence and structure, including deletions, inversions, and translocations. Currently, you can compare assemblies from over 50 annotated animal and plant genomes.

In a trio of studies published on June 27 in the journal Nature Microbiology 0, researchers at The University of Texas at Austin have discovered “fingerprints” of mysterious viruses hidden in an ancient group of microbes that may include the ancestors of all complex life on Earth: from fungi to plants to humans.

Ths discovery is significant; it explores the hypothesis that viruses were imperative to the evolution of humans and other complex life forms.

These microbes – known as Asgard archaea after the abode of the gods in Norse mythology – are usually found in the frigid sediments deep in the ocean and in boiling springs, and existed on Earth before the first eukaryotic cells, which carry their DNA inside a nucleus.

Cosmologist, noted author, Astronomer Royal and recipient of the 2015 Nierenberg Prize for Science in the Public Interest Lord Martin Rees delivers a thought-provoking and insightful perspective on the challenges humanity faces in the future beyond 2050. [3/2016] [Show ID: 30476]

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Science and technology continue to change our lives. University of California scientists are tackling the important questions like climate change, evolution, oceanography, neuroscience and the potential of stem cells.

UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California — teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world.

Researchers at North Carolina State University show that an important gene in maize called HPC1 modulates certain chemical processes that contribute to flowering time, and has its origins in “teosinte mexicana,” a precursor to modern-day corn that grows wild in the highlands of Mexico. The findings provide insight into plant evolution and trait selection, and could have implications for corn and other crops’ adaptation to low temperatures.

“We are broadly interested in understanding how natural variation of lipids are involved in the growth and development of plants, and how these compounds may help plants adapt to their immediate environments,” said Rubén Rellán-Álvarez, assistant professor of structural and molecular biochemistry at NC State and the corresponding author of a paper describing the research. “Specifically, we wanted to learn more about variation in lipids called phospholipids, which consist of phosphorus and fatty acids, and their role in adaptation to cold, low phosphorus, and the regulation of important processes for plant fitness and yield like flowering time.”

Maize grown at higher altitudes, like the highlands of Mexico, needs special accommodations in order to grow successfully. The colder temperatures in these mountainous regions put maize at a slight disadvantage when compared with maize grown at lower elevations and higher temperatures.

New research suggests that Darwinian evolution could be happening up to four times faster than previously thought, based on an analysis of genetic variation.

The more genetic differences there are in a species, the faster evolution can happen, as certain traits die off and stronger ones get established. The team behind this latest study calls it the “fuel of evolution”, and they looked at data on 19 different wild animal groups around the world.

That data analysis revealed this raw material for evolution is more abundant than earlier estimates, and as a result we may have to adjust our expectations for how quickly animals evolve – a pertinent question in our age of climate change.