Toggle light / dark theme

ReadCoor will commercialize the Wyss Institute’s (FISSEQ) fluorescent in situ RNA sequencing technology

Boston-based startup completes $23 million Series A financing to leverage novel imaging platform of gene locations towards gaining diagnostic insights and delivering therapeutics for cancer, immuno-oncology, infectious diseases, neurological and neuromuscular diseases, brain function and cognitive disorders

BOSTON—()—ReadCoor, Inc., today announced completion of an oversubscribed $23 million Series A financing round and its concurrent launch from Harvard University’s Wyss Institute for Biologically Inspired Engineering. ReadCoor will commercialize the Wyss Institute’s FISSEQ (fluorescent in situ sequencing) technology.

Nanosensors help understand how tumors will respond to therapies

MIT researchers have designed nanosensors that can profile tumors and may yield insight into how they will respond to certain therapies. The system is based on levels of enzymes called proteases, which cancer cells use to remodel their surroundings.

Once adapted for humans, this type of sensor could be used to determine how aggressive a tumor is and help doctors choose the best treatment, says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science and a member of MIT’s Koch Institute for Integrative Cancer Research.

“This approach is exciting because people are developing therapies that are protease-activated,” Bhatia says. “Ideally you’d like to be able to stratify patients based on their protease activity and identify which ones would be good candidates for these therapies.”

Stopping Light: Physicists Move Quantum Computers Closer to Reality

Hmmm; like the graphic reminds of one of my posts.


In Brief.

  • Quantum computers would run some 100 million times faster than your PC, but they have proven to be a monumental feat of engineering.
  • In a new experiment, physicists managed to stop light, which helps us overcome challenges and brings us close to optical quantum computing.

A team of researchers at The Australian National University (ANU) may have found another work-around to bring us closer to quantum computing: The physicists have managed to find a new way to stop light.

Light was trapped by shining infrared lasers into ultra-cold atomic vapor. While the atoms absorbed some photons, a large amount were left in a frozen state in the atomic cloud — enhancing photon interaction with atoms or other photons.

Promising biomaterial to build better bones with 3D printing

A Northwestern Engineering research team has developed a 3D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic “bone” material, whose shape can be easily customized, one day could be especially useful for the treatment of bone defects in children.

Bone implantation surgery is never an easy process, but it is particularly painful and complicated for children. With both adults and children, often times bone is harvested from elsewhere in the body to replace the missing bone, which can lead to other complications and pain. Metallic implants are sometimes used, but this is not a permanent fix for growing children.

“Adults have more options when it comes to implants,” said Ramille N. Shah, who led the research. “Pediatric patients do not. If you give them a permanent implant, you have to do more surgeries in the future as they grow. They might face years of difficulty.”

Soon, Tesla Cars Could Power the Grid (and Our Homes)

In Brief.

Tesla and SolarCity are working on making their cars capable of powering a household, and even the entire grid. Using vehicle-to-grid technology, Tesla may be on to something here, and its more than just saving on your electric bills.

Earlier this year, Elon Musk bought SolarCity for at least $2.6 billion, merging the solar engineering company with Tesla. Since then, both have been busy working on a few things. Perhaps the most interesting of these is the promise to cut down on your household electric bill.

A Primer for Deterministic Thermodynamics and Cryodynamics

A Primer for Deterministic Thermodynamics and Cryodynamics

Dedicated to the Founder of Synergetics, Hermann Haken

Otto E. Rossler, Frank Kuske, Dieter Fröhlich, Hans H. Diebner, Thimo Bo¨ hl, Demetris T. Christopoulos, Christophe Letellier

Abstract The basic laws of deterministic many-body systems are summarized in the footsteps of the deterministic approach pioneered by Yakov Sinai. Two fundamental cases, repulsive and attractive, are distinguished. To facilitate comparison, long-range potentials are assumed both in the repulsive case and in the new attractive case. In Part I, thermodynamics – including the thermodynamics of irreversible processes along with chemical and biological evolution – is presented without paying special attention to the ad hoc constraint of long-range repulsion. In Part II, the recently established new fundamental discipline of cryodynamics, based on long-range attraction, is described in a parallel format. In Part III finally, the combination (“dilute hot-plasma dynamics”) is described as a composite third sister discipline with its still largely unknown properties. The latter include the prediction of a paradoxical “double-temperature equilibrium” or at least quasi-equilibrium existing which has a promising technological application in the proposed interactive local control of hot-plasma fusion reactors. The discussion section puts everything into a larger perspective which even touches on cosmology.
Keywords: Sinai gas, chaos theory, heat death, dissipative structures, second arrow, Point Omega, Super Life, paradoxical cooling, antifriction, paradoxical acceleration, Sonnleitner numerical instability, dilute-plasma paradigm, two-temperature equilibrium, ITER, MHD, interactive plasma cooling, McGuire reactor, Hubble law, Zwicky rehabilitated, Perlmutter-Schmidt-Riess wiggle, mean cosmic temperature, van Helmont, Lavoisier, Kant, Poincaré, double-faced Sonnleitner map. (August 26, 2016)

Otto E. Rossler, Frank Kuske, Dieter Fro¨ hlich, Thimo Bo¨ hl
Division of Theoretical Chemistry, University of Tübingen, Auf der Morgenstelle 18, 72076 Tu¨ bingen, Germany

Hans H. Diebner
Department of Medical Informatics, Technical University Dresden, Blasewitzerstr. 86,
01307 Dresden, Germany

Demetris T. Christopoulos
National and Kapodistrian University of Athens, Department of Economics, Sofokleous 1 str.,
10509 Athens, Greece

Christophe Letellier
Physics Department, University of Rouen CORIA, Avenue de l’Université, 76801 Saint-Étienne-du-Rouvray, France

Full paper: http://environmental-safety.webs.com/Deterministic_Thermo_Cryo.pdf

Lawrence Krauss Versus Freeman Dyson on Gravitons

Yesterday, in the New York Review of Books, Freeman Dyson analyzed a trio of recent books on humanity’s future in the larger cosmos. They were How to Make a Spaceship: A Band of Renegades, an Epic Space Race, and the Birth of Private Spaceflight; Beyond Earth: Our Path to a New Home in the Planets; and All These Worlds Are Yours: The Scientific Search for Alien Life.

Dyson is “a brilliant physicist and contrarian,” as the theoretical astrophysicist Lawrence Krauss recently told Nautilus. So I was waiting, as I read his review, to come across his profound and provocative pronouncement about these books, and it came soon enough: “None of them looks at space as a transforming force in the destiny of our species,” he writes. The books are limited in scope by looking at the future of space as a problem of engineering. Dyson has a grander vision. Future humans can seed remote environments with genetic instructions for countless new species. “The purpose is no longer to explore space with unmanned or manned missions, but to expand the domain of life from one small planet to the universe.”

Dyson can be just as final in his opinions on the destiny of scientific investigation. According to Krauss, Dyson once told him, “There’s no way we’re ever going to measure gravitons”—the supposed quantum particles underlying gravitational forces—“because there’s no terrestrial experiment that could ever measure a single graviton.” Dyson told Krauss that, in order to measure one, “you’d have to make the experiment so massive that it would actually collapse to form a black hole before you could make the measurement.” So, Dyson concluded, “There’s no way that we’ll know whether gravity is a quantum theory.”

Room temperature magnetoelectric material created — Uses for next generation computing

Multiferroics – materials that exhibit both magnetic and electric order – are of interest for next-generation computing but difficult to create because the conditions conducive to each of those states are usually mutually exclusive. And in most multiferroics found to date, their respective properties emerge only at extremely low temperatures.

Two years ago, researchers in the labs of Darrell Schlom, the Herbert Fisk Johnson Professor of Industrial Chemistry in the Department of Materials Science and Engineering, and Dan Ralph, the F.R. Newman Professor in the College of Arts and Sciences, in collaboration with professor Ramamoorthy Ramesh at UC Berkeley, published a paper announcing a breakthrough in multiferroics involving the only known material in which magnetism can be controlled by applying an electric field at room temperature: the multiferroic bismuth ferrite.

READ MORE ON CORNELL UNIVERSITY | CORNELL CHRONICLE

Passive Liquid Flow Can Aid Nanotechnology Development, Study Suggests

Again organic nature teaches technology.


A new study, inspired by water’s movement from roots to leaves in tall trees, shows that a certain kind of passive liquid flow, where liquids naturally move in response to surface atomic interactions instead of being driven by external forces like pumps, is remarkably strong. By virtually modeling the way atoms interact at a solid surface, College of Engineering and Computer Science researchers suggest that passive liquid flow could serve as a highly efficient coolant-delivery mechanism without the need for pumps. The results, published in Langmuir, also have implications for the development of new nanoscale technology.