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Novel Therapy Developed for Aggressive Melanoma Subtype

Neuroblastoma RAS viral oncogene homolog (NRAS)-mutant melanoma is an aggressive form of skin cancer that develops because of a RAS genetic mutation within the cells. It is a common mutation in melanoma and accounts for 15–20% of melanoma diagnoses. An individual has greater risk of melanoma when exposed to the sun for extended periods of time. Additionally, individuals may have family history of melanoma that would increase their risk. It is important to regularly visit the dermatologist to confirm pigmented or non-pigmented moles are not cancerous. To evaluate each mole doctor’s access the change in shape, color, size, and unusual growth as time progresses.

Melanoma, specifically the NRAS subtype, can grow rapidly and spread to other areas of the body. Symptoms may also include change in nail appearance, eye issues, and mouth sores. While dependent on the stage of cancer, treatment usually includes drugs that target the NRAS pathway. Immunotherapeutic approaches include a checkpoint inhibitor treatment that activates immune cell response. Other forms of treatment include surgery and combination therapy. Scientists are working to learn more about NRAS melanoma and how to develop better treatments. Recent work has shown particular promise of treating NRAS melanoma in the lab and clinic.

A recent article in Cancer Immunology Research, by Dr. Keiran Smalley and others, demonstrated that blocking the RAS pathway in NRAS-mutated melanoma cells limit tumor growth and expansion. Smalley is a Professor and Scientific Director in the Donald A. Adam Comprehensive Melanoma Research Center of Excellence at Moffitt Cancer Center. His work focuses on understanding melanoma and the immune response after therapeutic treatment. In addition, Smalley is interested in using computational biology and other techniques to not only assess therapeutic benefit but develop novel treatments specific to mutated melanoma cells.

3D-object-making machine forgoes printing for knitting

If you find 3D printers to be just a little too coldly futuristic, this contraption might be more to your liking. Scientists from Cornell University have created a machine that knits solid 3D objects out of nice old-timey conventional yarn.

The prototype device is made mainly of 3D-printed components, and incorporates a bed of knitting needles arranged in a 6 × 6 block. A motorized knitting head dispenses yarn to any of those needles in sequence, as determined by a program on a computer that’s controlling it.

Each of the needles in turn consists of a 3D-printed symmetrical double hook connected to a brass support tube. Because the front and rear sections of the hook move independently, it’s possible for the device to either knit or purl, depending on which section of the hook picks up the first loop of yarn.

Two independent quantum networks successfully fused into one

Many quantum researchers are working toward building technologies that allow for the existence of a global quantum internet, in which any two users on Earth would be able to conduct large-scale quantum computing and communicate securely with the help of quantum entanglement. Although this requires many more technological advancements, a team of researchers at Shanghai Jiao Tong University in China have managed to merge two independent networks, bringing the world a bit closer to realizing a quantum internet.

A true global will require interconnectivity between many networks, and this has proven to be a much more difficult task for than it is for classical networks. While researchers have demonstrated the ability to connect quantum computers within the same network, multi-user fusion remains a major challenge. Fully connected networks using dense wavelength division multiplexing (DWDM) have been achieved, but have scalability and complexity issues.

However, the research team involved in the new study, published in Nature Photonics, has merged two independent networks with 18 different users. All 18 users can communicate securely using -based protocols using this method. This represents the most complex multi-user quantum network to date.

Ultra-thin 3D display delivers wide-angle, highly-detailed images

Researchers have developed an ultra-thin 3D display with a wide viewing angle, clear image quality and vivid display depth. By overcoming tradeoffs that typically limit glasses-free 3D displays, the advance could open new possibilities for highly detailed interactive experiences in health care, education and entertainment.

“The new display is just 28 mm thick, dramatically slimmer than conventional directional backlight systems, which typically exceed 500 mm,” said research team leader Xu Liu, from Zhejiang University in China. “This level of compactness, combined with the substantial boost in resolution we achieved, represents an important step toward making the technology practical for real-world products.”

In Optica, the researchers demonstrate an ultra-slim 32-inch directional backlight-based prototype based on the new display design. The prototype is roughly the size of a large computer monitor, has a wide viewing angle of over 120° and a large 3D display volume of 28 × 16 × 39 inches.

Scientists reveal it is feasible to send quantum signals from Earth to a satellite

Quantum satellites currently beam entangled particles of light from space down to different ground stations for ultra-secure communications. New research shows it is also possible to send these signals upward, from Earth to a satellite; something once thought unfeasible.

This breakthrough overcomes significant barriers to current quantum communications. Ground station transmitters can access more power, are easier to maintain and could generate far stronger signals, enabling future quantum computer networks using satellite relays.

The study, “Quantum entanglement distribution via uplink satellite channels”, by Professor Simon Devitt, Professor Alexander Solntsev and a research team from the University of Technology Sydney (UTS), is published in the journal Physical Review Research.

“We Made the World’s Best Material” — How a Diamond Substitute Could Revolutionize Quantum Computing

Strontium titanate’s remarkable ability to perform at extremely low temperatures makes it a key material for next-generation cryogenic devices used in quantum computing and space exploration. Superconductivity and quantum computing have moved beyond theoretical research to capture the public’s im

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