Cryptocurrency is usually “mined” through the blockchain by asking a computer to perform a complicated mathematical problem in exchange for tokens of cryptocurrency. But in research appearing in the journal Chem a team of chemists has repurposed this process, asking computers to instead generate the largest network ever created of chemical reactions which may have given rise to prebiotic molecules on early Earth.
This work indicates that at least some primitive forms of metabolism might have emerged without the involvement of enzymes, and it shows the potential to use blockchain to solve problems outside the financial sector that would otherwise require the use of expensive, hard to access supercomputers.
“At this point we can say we exhaustively looked for every possible combination of chemical reactivity that scientists believe to had been operative on primitive Earth,” says senior author Bartosz A. Grzybowski of the Korea Institute for Basic Science and the Polish Academy of Sciences.
A novel nanoparticle spray coating process has been shown to all but eliminate the growth of some of the world’s most dangerous bacteria in air filtration systems, significantly reducing the risk of airborne bacterial and viral infections.
That’s the principal finding of a study, led by researchers from IMDEA Materials Institute in collaboration with scientists from the Networking Biomedical Research Center in Respiratory Diseases (CIBERES) and Rey Juan Carlos University (URJC) in Madrid, Spain. The study was published in Materials Chemistry and Physics.
The study, “Control of microbial agents by functionalization of commercial air filters with metal oxide particles,” tested various spray coatings of silver (Ag2O), copper (CuO) and zinc (ZnO) oxides as low-cost antiviral and antibacterial filters when applied to commercially available air filtration systems.
Researchers discovered a method to expedite the study of bacterial gene regulation, which could help fight antibiotic resistance by analyzing DNA replication’s impact on gene expression.
Bacterial infections cause millions of deaths each year, with the global threat made worse by the increasing resistance of the microbes to antibiotic treatments. This is due in part to the ability of bacteria to switch genes on and off as they sense environmental changes, including the presence of drugs. Such switching is accomplished through transcription, which converts the DNA in genes into its chemical cousin in mRNA, which guides the building of proteins that make up the microbe’s structure.
For this reason, understanding how mRNA production is regulated for each bacterial gene is central to efforts to counter resistance, but approaches used to study this regulation to date have been laborious. In a new study, scientists revealed a trick that may speed such efforts.
Tunneling is one of most fundamental processes in quantum mechanics, where the wave packet could traverse a classically insurmountable energy barrier with a certain probability.
On the atomic scale, tunneling effects play an important role in molecular biology, such as accelerating enzyme catalysis, prompting spontaneous mutations in DNA and triggering olfactory signaling cascades.
Photoelectron tunneling is a key process in light-induced chemical reactions, charge and energy transfer and radiation emission. The size of optoelectronic chips and other devices has been close to the sub-nanometer atomic scale, and the quantum tunneling effects between different channels would be significantly enhanced.
The use of NISQ devices for useful quantum simulations of materials and chemistry is still mainly limited by the necessary circuit depth. Here, the authors propose to combine classically-generated effective Hamiltonians, hybrid fermion-to-qubit mapping and circuit optimisations to bring this requirement closer to experimental feasibility.
Chemical analysis of rocks found in South Africa shows that ancient microorganisms sustained themselves in a variety of ways, adding to evidence for an early origin of life on Earth.
The humble membranes that enclose our cells have a surprising superpower: They can push away nano-sized molecules that happen to approach them. A team including scientists at the National Institute of Standards and Technology (NIST) has figured out why, by using artificial membranes that mimic the behavior of natural ones. Their discovery could make a difference in how we design the many drug treatments that target our cells.
The team’s findings, which appear in the Journal of the American Chemical Society, confirm that the powerful electrical fields that cell membranes generate are largely responsible for repelling nanoscale particles from the surface of the cell.
This repulsion notably affects neutral, uncharged nanoparticles, in part because the smaller, charged molecules the electric field attracts crowd the membrane and push away the larger particles. Since many drug treatments are built around proteins and other nanoscale particles that target the membrane, the repulsion could play a role in the treatments’ effectiveness.
The ‘ten electron’ rule provides guidance for the design of single-atom alloy catalysts for targeted chemical reactions.
A collaborative team across four universities have discovered a very simple rule to design single-atom alloy catalysts for chemical reactions. The ‘ten electron rule’ helps scientists identify promising catalysts for their experiments very rapidly. Instead of extensive trial and error experiments of computationally demanding computer simulations, catalysts’ composition can be proposed simply by looking at the periodic table.
Single-atom alloys are a class of catalysts made of two metals: a few atoms of reactive metal, called the dopant, are diluted in an inert metal (copper, silver, or gold). This recent technology is extremely efficient at speeding up chemical reactions but traditional models don’t explain how they work.