Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 958

A.I. Could Solve Some of Humanity’s Hardest Problems. It Already Has

Since the release of ChatGPT, huge amounts of attention and funding have been directed toward chatbots. These A.I. systems are trained on copious amounts of human-generated data and designed to predict the next word in a given sentence. They are hilarious and eerie and at times dangerous.

But what if, instead of building A.I. systems that mimic humans, we built those systems to solve some of the most vexing problems facing humanity?

In 2020, Google DeepMind unveiled AlphaFold, an A.I. system that uses deep learning to solve one of the most important challenges in all of biology: the so-called protein-folding problem. The ability to predict the shape of proteins is essential for addressing numerous scientific challenges, from vaccine and drug development to curing genetic diseases. But in the 50-plus years since the protein-folding problem had been discovered, scientists had made frustratingly little progress.

Enter AlphaFold. By 2022, the system had identified 200 million protein shapes, nearly all the proteins known to humans. And DeepMind is also building similar systems to accelerate efforts at nuclear fusion and has spun off Isomorphic Labs, a company developing A.I. tools for drug discovery.

Demis Hassabis is the chief executive of Google DeepMind and the leading architect behind AlphaFold. So I asked him on the show to talk me through how AlphaFold actually works, the kinds of problems similar systems could solve and what an alternative pathway for A.I. development could look like.

Mentioned:

Continue reading “A.I. Could Solve Some of Humanity’s Hardest Problems. It Already Has” | >

Is Glutamate A Marker Of Low NAD?

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Discount Links:
At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten.
Use Code: CONQUERAGING At Checkout.

NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout.

Epigenetic Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ6…M0&irgwc=1
Use Code: CONQUERAGING

At-Home Blood Testing (SiPhox Health): https://getquantify.io/mlustgarten.

Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten.

Continue reading “Is Glutamate A Marker Of Low NAD?” | >

Advancing human healthspan: Longevity Summit Dublin’s agenda unveiled

The Longevity Summit Dublin is dedicated to the recognition of emerging research developments aimed at extending the human healthspan. This much-anticipated event brings together leading scientists from around the world, fostering collaboration and knowledge exchange in pursuit of this critical objective.

The summit serves as a premier platform for showcasing the latest research and innovations within the longevity industry. Notably, keynote presentations by esteemed experts in the aging field provide valuable insights into the advancements being made towards enhancing overall well-being and extending lifespans.

Longevity. Technology: Scheduled to take place from the 17th to the 20th of August 2023, the Longevity Summit Dublin boasts a remarkable lineup of over 40 pioneering scientists, researchers and executives, as well as high net-worth investors – all of the attendees share a common focus on addressing the challenges posed by chronic diseases.

Is breast cancer more common on the left side?

A study published in Nature last fall suggests that breast cancer is slightly more common on the left side of the body than it is on the right. That same study also indicates that left-sided breast cancer is more aggressive and associated with poorer treatment outcomes.

But what does that mean for people with breast cancer? And, is there anything you can do about it if you have left-sided breast cancer? We went to medical oncologist Giancarlo Moscol, M.D., who specializes in the treatment of breast cancers. Here’s what he shared.

So, is breast cancer more common on the left side than on the right?

Editorial: Augmentation of Brain Function: Facts, Fiction and Controversy

This research topic consists of 148 articles on various aspects of brain augmentation contributed by more than 600 authors. At the time of writing, the articles have been viewed online more than 1.3 million times and received plentiful citations in the scientific literature. The topic won the 2017 Frontiers Spotlight Award.

The topic theme, “Augmentation of brain function,” is an umbrella term for the approaches from different disciplines, aimed at the improvement of brain performance in both healthy people and patients suffering from neurological disabilities. Functions of the brain that scientists hope to augment belong to sensory, motor and cognitive domains. Brain enhancements could be achieved pharmacologically or using neurostimulation. Functional improvements can be also achieved with brain training techniques that employ modern technologies like computer games and virtual reality. Furthermore, brain performance can be augmented using brain-machine interfaces (BMIs), the pathways that connect neuronal circuits to external assistive devices, such as limb prostheses, exoskeletons, and communication aids. In addition to sending commands to external devices, BMIs can enable bidirectional communications, where artificial sensory signals are delivered to the brain while information is being decoded from neural recordings.

Even though many of the brain-augmenting ideas sound like science fiction, the topic authors feel optimistic about most of them. The overall consensus is that brain performance can be improved with artificial components, and this approach will lead to practical applications in the not-too-distant future. Many of the techniques covered in the topic, for example BMIs and noninvasive stimulation, have already experienced an explosive development. While expectations are high for the augmentation approaches, philosophers are warning about the ethical issues related to technologies that interfere with the mind, possibly in unpredictable ways. Although some of these concerns seem far-fetched, it is important that ethical standards are kept high as these revolutionary brain-augmenting methods are being developed.

Cutting Edge Levitation Technologies Aim to Revolutionize Bioprinting and Space Travel

A new project is using cutting-edge levitation techniques to make bioprinting heart models and other complex tissues a reality.

Dubbed PULSE, the project combines the recently developed techniques of acoustic levitation and magnetic levitation to manipulate individual components without actually touching them. It’s a process that the researchers involved hope will one day facilitate the bioprinting of organs and other human tissues in much greater detail and complexity than what is achievable with current techniques.

If perfected, the researchers also hope this type of bioprinting could even help on long-term space missions as more accurate organ models can create more accurate defenses against radiation and other stresses of space travel.

Could Rotifers be the Next Great Laboratory Model?

Rotifers are multicellular, microscopic marine animals that live in soils and freshwater environments. They are transparent and can be easily grown in large numbers. As such, they have been used in some laboratories as research subjects for many years. Now scientists have found a way to manipulate the rotifer genome, which can make them far more useful for many different research applications.

In new work reported in PLOS Biology, scientists used the CRISPR-Cas9 gene editing tool to alter two rotifer genes. These edits were then passed down to future generations of rotifers. This effort can now help others use these organisms in their laboratories.

Fast-Spreading EG.5 Coronavirus Variant Sparks Global Concerns

Disclaimer: It’s important to note that this article is solely intended for educational and informational purposes, and no affiliate links are included. The outline for this article was written with the help of AI. All information is open and available to the public.

Emerging Threat: EG.5 Variant Raises Global Concerns

A new and fast-spreading variant of the coronavirus, known as EG.5, is causing worries worldwide. This variant is contributing to at least 8% of new COVID-19 cases, a significant increase from the previous month. To help us understand this situation, we’re joined by Dr. Bob, the Director of the Institute for Autoimmune and Rheumatic Diseases at St. Joseph Health, and an expert in this field.

/* */