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Category: biotech/medical – Page 941

Cleveland Clinic Study Shows Deep Brain Stimulation Encouraging for Stroke Patients

Click image for animation of DBS for post-stroke rehabilitation

A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients by Cleveland Clinic researchers has shown that using DBS to target the dentate nucleus – which regulates fine-control of voluntary movements, cognition, language, and sensory functions in the brain – is safe and feasible.

The EDEN trial (Electrical Stimulation of the Dentate Nucleus for Upper Extremity Hemiparesis Due to Ischemic Stroke) also shows that the majority of participants (nine out of 12) demonstrated improvements in both motor impairment and function. Importantly, the study found that participants with at least minimal preservation of distal motor function at enrollment showed gains that almost tripled their initial scores.

Researchers find risk of premature birth 50% higher in mothers with poor mental health

New work led by researchers at the University of Exeter, King’s College London, the London School of Hygiene and Tropical Medicine and the University of Liverpool has found that women who had at least one contact with mental health services in the seven years prior to their pregnancy were at increased risk of preterm birth.

The study, “Obstetric and neonatal outcomes in pregnant women with and without a history of specialist mental care: a national population-based cohort study using linked routinely collected data in England,” published in Lancet Psychiatry, analyzed data from more than two million , and found that one in 10 women who had used mental health services before their pregnancy had a , compared to one in 15 in those who had not.

Researchers also found that women who had used mental health services faced a higher risk of giving birth to a baby that was small for its gestational age, increasing from 65 per 1,000 births in women who had not used mental health services to 75 per 1,000 births in women who had.

Hand-held tube containing aluminum foil balls produces enough electricity to power LED array when shaken

A team of mechanical engineers from Chung-Ang University, Massachusetts General Hospital, LS Materials and Yonsei University has found that a hand-held cylinder containing crumpled aluminum foil balls is capable of producing enough electricity when shaken to light a small LED grid. In their paper published in the journal Advanced Science, the group describes other materials used in the cylinder and possible uses for such a device.

Prior research has shown that a wide variety of materials can be used to generate , and that some constructions can capture that . Researchers have suggested such devices could be useful as the power needs of personal electronics decrease. In this new effort, the researchers have looked to aluminum foil as a material for generating static electricity and capturing it to power an external device.

The device the team built is shaped as a with a cap on the top and bottom—about the size of a Pringle’s can. The tube was made using an acrylic substrate covered with a polytetrafluoroethylene layer. The caps, which serve as electrodes, were made of aluminum. The team then crumpled three wads of into balls and placed them inside the tube.

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Australian Researchers Create Technique for Engineering Blood Vessels Using Natural Tissue

Blood vessels form the transportation network within our bodies. They are streets where red and white blood cells drive. They are the delivery system to oxygenate our brain and other vital organs and muscles. There are other highways in our bodies such as our nervous and lymphatic systems, but blood vessels are the ones that are central to healthy heart function and keeping our brain supplied with oxygen. When blood vessels are compromised we can suffer a stroke, heart attack, aneurysm or die.

When usual causes of heart attacks are blocked coronary arteries. The coronary arteries supply blood and oxygen to the heart. When partially blocked people experience symptoms like angina. When blocked they can suffer a myocardial infarction, the fancy name for a heart attack.

Today, harvested blood vessel grafts from human donors or the patient are used for bypassing coronary blood vessel blockages. But researchers at the University of Melbourne believe that fabricated blood vessel tissue that can be shaped to any need would be an effective substitute for existing grafts. The team in its search for a graft alternative has combined a variety of materials and living tissue with a fabrication technique to create complex blood vessels that can serve multiple purposes.

Scientific Proof We Can Reverse Aging | Raj Agni Podcast

Scientist, longevity expert and biotechnology patent holder Raj Agni (aka Steven Schorr) beams in to discuss age deceleration, telomere extension and revolutionary plant-based anti-aging supplements on episode 114 of the Far Out with Faust podcast.

Raj Agni, also known as Steven M. Schorr, is a metaphysician, author, inventor, healer, alchemist, artist, musician, entrepreneur, and creator of Extended Longevity products designed to rebuild your telomeres. His clinics have operated for 14 years on Maui, Hawaii and he has treated over twenty thousand people.

Raj has authored 20 U.S. and International Patents, including his patent on the aeroponic technology, and four patents for innovations in the Airponic™ process and product design. Raj is a published author whose books include “Keeper of Secrets, 1997, a translation of the Yoga Sutras of Patanjali, ” Perceptions of Truth”; 2013, and ” The Path to an Illuminated Awakening”, published in 2014. These books are currently available on Amazon.com.

In this episode, Raj catches Faust up on the anti-aging and age reversal insights and results he’s found since his first appearance on episode 18. He delves into these topics, and more:

-Can you stop, or even reverse, aging?
–How does aging work?
–What are telomeres?
–Are there supplements that can reverse aging?
–How can you test to see what your biological age is?
–What should you do if you have lingering side effects from the past three years?

This is Raj’s second appearance on the show. Link to episode 18: https://youtu.be/gxkGbO-jhY4

Continue reading “Scientific Proof We Can Reverse Aging | Raj Agni Podcast” | >

Scientists develop efficient spray technique for bioactive materials

Rutgers University scientists have devised a highly accurate method for creating coatings of biologically active materials for a variety of medical products. Such a technique could pave the way for a new era of transdermal medication, including shot-free vaccinations, the researchers said.

Writing in Nature Communications, the researchers described a new approach to deposition, an industrial spray-coating process. Essentially, the team developed a way to better control the target region within a spray zone as well as the electrical properties of microscopic particles that are being deposited. The greater command of those two properties means that more of the spray is likely to hit its microscopic target.

In electrospray deposition, manufacturers apply a to a flowing liquid, such as a biopharmaceutical, converting it into fine particles. Each of those droplets evaporates as it travels to a target area, depositing a solid precipitate from the original solution.

Genetics: how they impact disease risk, what you can do about it, testing & more [AMA 50 sneak peek]

Watch the full episode and view show notes here: https://bit.ly/3Oo9mE5
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In this “Ask Me Anything” (AMA) episode, Peter delves into the realm of genetics, unraveling its connection to disease and emphasizing the value of understanding one’s genetic risks. He elucidates essential background knowledge on genetics before delving into the myriad reasons why individuals might consider genetic testing. Peter differentiates scenarios where genetic testing provides genuine insights from those where it may not be as useful. From there, Peter explores a comprehensive comparison of commercial direct-to-consumer genetic tests, providing insights on interpreting results and identifying the standout options for gaining insights into personal health.

In this sneak peek, we discuss:
00:00 — Intro.
02:09 — Defining the term “genetics” and why it’s important.
04:03 — What is DNA, and how does it impact our biology and traits?
07:13 — How are genetics passed down from parent to child?
11:44 — How much do genes vary across individuals?
16:22 — Which traits are determined by genetics versus experience or environmental factors?
22:30 — Reasons for genetic testing.

In the full episode, we also discuss:
–What exactly is being measured by a genetic test?;
–Testing for monogenic disorders;
–Understanding polygenic risk;
–Is genetic testing more important for someone who doesn’t know their family history?;
–What does it mean to be positive for a particular variant?;
–What does it mean to be negative for a particular variant?;
–How does someone get genetic testing through their healthcare provider, and how are these tests performed?;
–The financial cost of various genetic tests;
–Could having a risk allele for a disease result in an increase in one’s insurance premium?;
–Other risks associated with genetic testing;
–How do commercial, direct-to-consumer genetic tests compare to the information one might receive from clinical genetic testing?;
–Are certain direct-to-consumer tests better than others?;
–How long until whole genome sequencing becomes genuinely useful?;
–How useful are personalized dietary recommendations based on genetics?;
–Final thoughts and advice regarding genetic testing; and.
–More.

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About:

The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.

Continue reading “Genetics: how they impact disease risk, what you can do about it, testing & more [AMA 50 sneak peek]” | >