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Category: biotech/medical – Page 831

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Scientists in Finland have developed a nanodevice that can measure the absolute power of microwave radiation down to the femtowatt level at ultra-low temperatures—a scale trillion times lower than routinely used in verifiable power measurements. The device has the potential to significantly advance microwave measurements in quantum technology.

Quantum science takes place mostly at using devices called dilution refrigerators. The experiments also have to be done at tiny energy levels—down to the energy level of single photons or even less. Researchers have to measure these extremely low energy levels as accurately as possible, which means also accounting for heat—a persistent problem for .

To measure heat in quantum experiments, scientists use a special type of thermometer called a bolometer. An exceptionally accurate bolometer was recently developed at Aalto University by a team led by Mikko Möttönen, associate professor of quantum technology at Aalto and VTT, but the device had more uncertainty than they had hoped for. Although it enabled them to observe the relative level, they couldn’t determine the absolute amount of energy very accurately.

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Scientists have found a way to restore the brain and spinal cord interface, developing an implantable device that enables paralyzed patient to stand and walk again.

A spinal cord injury (SCI) can be debilitating for some people, making it difficult for them to walk normally again. Some individuals may take weeks to recover their ability to walk after an injury, while others may take months or even suffer from paralysis.

This is mainly due to the SCI hindering communication between the brain and the region of the spinal cord responsible for limb movement.

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After three years of upgrading and waiting, due in part to the coronavirus pandemic, the Laser Interferometer Gravitational-wave Observatory has officially resumed its hunt for the signatures of crashing black holes and neutron stars.

“Our LIGO teams have worked through hardship during the past two-plus years to be ready for this moment, and we are indeed ready,” Caltech physicist Albert Lazzarini, the deputy director of the LIGO Laboratory, said in a news release.

Lazzarini said the engineering tests leading up to today’s official start of Observing Run 4, or O4, have already revealed a number of candidate events that have been shared with the astronomical community.

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With the new method, scientists can explore many cancer mutations whose roles are unknown, helping them develop new drugs that target those mutations.

MIT

MIT is an acronym for the Massachusetts Institute of Technology. It is a prestigious private research university in Cambridge, Massachusetts that was founded in 1861. It is organized into five Schools: architecture and planning; engineering; humanities, arts, and social sciences; management; and science. MIT’s impact includes many scientific breakthroughs and technological advances. Their stated goal is to make a better world through education, research, and innovation.

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In short blood dilution is very, very good for you.

In this talk, Dr. Irina Conboy discusses the role of repair and regeneration in lifespan and healthspan, contending that these factors, rather than entropy and time progression, truly govern our aging process. She describes the research her team is pursuing, investigating whether improving the efficiency of bodily repair in older individuals could effectively make them younger. She suggests that biological age could potentially be reversed and discusses heterochronic parabiosis and plasma dilution as potential ways to accomplish that. Conboy highlights recent research suggesting that old blood has a greater impact on cellular health and function than young blood. She presents her team’s experimental research on the rejuvenation effects of plasma dilution, demonstrating its significant impact on reducing senescence, neuroinflammation, and promoting neurogenesis in the brains of old mice.

00:00:00 — Importance of repair and regeneration in aging.
00:04:45 — Young blood vs. old blood, heterochronic parabiosis.
00:10:17 — Plasma dilution is key.
00:15:49 — Kiana Aran’s blood heterochronicity on a chip.
00:17:56 — The role of senescence in parabiosis and blood exchange.
00:27:53 — Measurements of biological age.
00:36:57 — Systemic calibration is globally rejuvenative.
00:37:30 — Conclusions.

About the Speaker:
Irina Conboy is a Professor at the University of California, Berkeley in the Department of Bioengineering. Her discovery of the rejuvenating effects of young blood through parabiosis in a seminal paper published in Nature in 2005 paved the way for a thriving field of rejuvenation biology. The Conboy lab currently focuses on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, elucidating the mechanisms underlying muscle stem cell aging, directed organogenesis, and making CRISPR a therapeutic reality.

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Autophagy is the process by which cells break down waste and gunk inside them.

There’s a cleaning process happening in our bodies daily. Derived from Greek, the process is called autophagy, which means self-eating.

It plays a vital role in immunity and host defense. In the human body, self-eating is the process by which our cells break down, remove abnormal proteins and old waste macromolecules and organelles in its cytoplasm, and kill invading microorganisms.

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The device can track body signals from tissues as deep as 164 mm for up to twelve hours at a time.

A team of researchers and scientists from the University of California San Diego have developed a stick-on ultrasound patch, also called an ultrasonic system-on-patch (USoP), which a person can wear on the go as the device gives insight on the blood pressure, heart rate, and other physiological signs of the subject wearing it.

As per the press release, the USoP tracks these body signals from tissues as deep as 164 mm for up to twelve hours at a time.

Lin et al.

As per the press release, the USoP tracks these body signals from tissues as deep as 164 mm for up to twelve hours at a time.

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A paralysed man has regained the ability to walk smoothly using only his thoughts for the first time, researchers said on Wednesday, thanks to two implants that restored communication between brain and spinal cord.

The patient Gert-Jan, who did not want to reveal his surname, said the breakthrough had given him “a freedom that I did not have” before.

The 40-year-old Dutchman has been paralysed in his legs for more than a decade after suffering a spinal cord injury during a bicycle accident.

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