Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 740

The threat group behind the fast-growing Rhysida ransomware-as-a-service operation has claimed credit for an Aug. 19 attack that crippled systems at Singing River Health System, one of Mississippi’s largest healthcare entities.

The attack follows one against California’s Prospect Medical Holdings in August that affected 16 hospitals and more than 160 clinics around the country. The wide scope of that incident prompted an alert from the Health Sector Cybersecurity Coordination Center to other organizations in the industry.

The attack on Singing River impacted three hospitals and some 10 clinics belonging to the system and is likely to reinforce Rhysida’s credentials as a growing threat to healthcare organizations in the US. It’s also a reminder of the surging interest in the sector from ransomware actors who, early in the COVID-19 pandemic, had piously vowed to stay away from attacking hospitals and other healthcare entities.

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A hairless, pale-skinned lamb lies on its side in what appears to be an oversized sandwich bag filled with hazy fluid. Its eyes are closed, and its snout and limbs jerk as if the animal — which is only about three-quarters of the way through its gestation period — is dreaming.

The lamb was one of eight in a 2017 artificial-womb experiment carried out by researchers at the Children’s Hospital of Philadelphia (CHOP) in Pennsylvania. When the team published its research1 in April of that year, it released a video of the experiments that spread widely and captured imaginations — for some, evoking science-fiction fantasies of humans being conceived and grown entirely in a laboratory.

Now, the… More.

US regulators will consider clinical trials of a system that mimics the womb, which could reduce deaths and disability for babies born extremely preterm.

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Scientists in Israel have created a model of a human embryo from stem cells in the laboratory, without using sperm, eggs or a womb, offering a unique glimpse into the early stages of embryonic development.

The model resembles an embryo at day 14, when it acquires internal structures but before it lays down the foundations for body organs, according to the team at Israel’s Weizmann Institute of Science.

The Israeli team emphasised that they were a long way from being able to create an embryo from scratch.

“The question is, when does an embryo model become considered an embryo? When that happens, we know the regulations. At the moment we are really, really far off from that point,” said team leader Jacob Hanna.

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Please attend our Virtual Realilty Ending Aging Forum!

This event will showcase the newest breakthroughs in rejuvenation biotechnologies happening at the SENS Research Foundation’s Research Center in Mountain View, CA, as well as the research funded at extramural labs.

The Forum will be hosted virtually through Meetaverse, a state-of-the-art Virtual Reality platform.

This virtual event is your opportunity to hear first-hand about the latest advances that our in-house researchers are making toward new rejuvenation biotechnologies, along with some of our young scientists-in-training and outside researchers whose research we fund.

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Summary: Researchers have unearthed how human brains inherently perform calculations akin to high-powered computers through Bayesian inference, enabling precise, swift environmental interpretation. This statistical method melds prior knowledge and new evidence, permitting us to quickly and accurately discern our surroundings.

This study showcases how our brain’s visual system structure is innately designed to execute Bayesian inference on the sensory data it gathers. Such revelations promise breakthroughs in areas spanning from AI’s machine learning to novel therapeutic strategies in clinical neurology.

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I hope this isn’t a duplicate but that’s amazing! I dunno if I shared the latest Google cloud security conference? It’s an hour and they’re using advanced AI and even collaborating with Israel I think.

After 17 medical consultations led to dead ends, a mother turned to ChatGPT for help. Then, AI came up with a diagnosis.

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Researchers have shown that high concentrations of key proteins in human breast milk, especially osteopontin and κ-casein, are associated with a greater abundance of two species of bacteria in the gut of babies: Clostridium butyricum and Parabacteroides distasonis, known to be beneficial for human health and used as probiotics. These results suggest that proteins in breast milk influence the abundance of beneficial gut microbes in infants, playing an important role in early immune and metabolic development

More than 320 million years of mammalian evolution has adapted breast milk to meet all the physiological needs of babies: it contains not only nutrients, but also hormones, antimicrobials, digestive enzymes, and growth factors. Furthermore, many of the proteins in breast milk, for example casein and milk fat globule membrane proteins, aren’t just sources of energy and molecular building blocks, but also directly stimulate immunity, at least under preclinical conditions.

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Naked mole rats are rodents that are about the size of a mouse with a key difference, aside from having no fur — they’re extremely long-lived — reaching ages of around 40 years old. For comparison, lab mice live an average of about three and a half years. To explain their extensive lifespans, researchers have sought to pinpoint how naked mole rats evade the onset of age-related diseases like cancer. In doing so, they’ve identified a form of gelatinous substance called hyaluronan, which has anti-inflammatory and anticancer properties. Now, the question of whether the benefits of the naked mole rat’s abundant levels of this form of hyaluronan — called high molecular mass hyaluronic acid (HMM-HA) — can be exported to other species has recently drawn attention.

Published in Nature, Gorbunova and colleagues from the University of Rochester show that genetically modifying mice to harbor an enzyme that produces HMM-HA extends their lifespan. The researchers go on to show that increasing HMM-HA reduces the prevalence of cancer. Additionally, the nmrHAS2 gene improves the healthspan of mice by countering physiological dysfunction, as measured with a frailty score. These findings provide the first evidence that genes from long-lived species can be exported to other species, perhaps conferring benefits to humans one day.

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Flat screen TVs that incorporate quantum dots are now commercially available, but it has been more difficult to create arrays of their elongated cousins, quantum rods, for commercial devices. Quantum rods can control both the polarization and color of light, to generate 3D images for virtual reality devices.

Using scaffolds made of folded DNA, MIT engineers have come up with a new way to precisely assemble arrays of quantum rods. By depositing quantum rods onto a DNA scaffold in a highly controlled way, the researchers can regulate their orientation, which is a key factor in determining the polarization of light emitted by the array. This makes it easier to add depth and dimensionality to a virtual scene.

“One of the challenges with quantum rods is: How do you align them all at the nanoscale so they’re all pointing in the same direction?” says Mark Bathe, an MIT professor of biological engineering and the senior author of the new study. “When they’re all pointing in the same direction on a 2D surface, then they all have the same properties of how they interact with light and control its polarization.”

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