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Two lifeforms merge in once-in-a-billion-years evolutionary event

Scientists have caught a once-in-a-billion-years evolutionary event in progress, as two lifeforms have merged into one organism that boasts abilities its peers would envy. Last time this happened, Earth got plants.

The phenomenon is called primary endosymbiosis, and it occurs when one microbial organism engulfs another, and starts using it like an internal organ. In exchange, the host cell provides nutrients, energy, protection and other benefits to the symbiote, until eventually it can no longer survive on its own and essentially ends up becoming an organ for the host – or what’s known as an organelle in microbial cells.

Imagine if kidneys were actually little animals running around, and humans had to manually filter their blood through a dialysis machine. Then one day some guy somehow gets one of these kidney critters stuck… Internally (who are we to judge how?) – and realizes he no longer needs his dialysis machine. Neither do his kids, until eventually we’re all born with these helpful little fellas inside us. That’s kind of what’s happening here.

Intermittent Fasting Linked to Vastly Increased Chance of Heart Attack and Stroke

This regimented approach to dieting has helped many people achieve the discipline they need to lose weight, and some research has shown that it can provide a myriad of health benefits, including improved blood pressure.

But a new yet-to-be-published study, presented this week at a meeting of the American Heart Association, suggests that intermittent fasting could have serious consequences for your cardiovascular health.

In an analysis of over 20,000 US adults, the study found that those who eat in just an eight hour window or less per day — thereby fasting for at least 16 hours — had a 91 percent higher chance of dying from heart disease.

Rare black-footed ferrets successfully cloned from frozen tissue samples

Noreen and Antonia were born back in February, but the organisation announced the news on Thursday, local time.

Both are healthy and continue to reach expected development and behavioural milestones.

Noreen was born at the National Black-footed Ferret Conservation Center in Colorado, while Antonia resides at the Smithsonian’s National Zoo and Conservation Biology Institute in Virginia.

New Vaccine Could Protect Against Any Strain of a Virus With One Shot

Scientists seem to be close to creating a “one-and-done” vaccine that can protect against any strain of a virus with just one shot.

In a press release from the University of California — Riverside, one of the researchers behind the new RNA vaccine, Rong Hai, explained why he and his colleagues are so excited about their experimental — and allegedly universal — shot.

“What I want to emphasize about this vaccine strategy is that it is broad,” said Hai, a virologist and coauthor of a new paper on the vaccine candidate in the Proceedings of the National Academy of Sciences. “It is broadly applicable to any number of viruses, broadly effective against any variant of a virus, and safe for a broad spectrum of people.”

Forms of life, forms of mind

We lost a really great human today – philosopher Daniel C. Dennett.

Dan was a kind, honest, generous guy. He had a brilliant mind – insightful, critical, with an encyclopedic knowledge of pithy analogies and clinical examples (“intuition pumps” he called them), as well as who came up with them. And despite all of his experience and accomplishments, he always had a kind of childish excitement about new ideas, and new experiments. What he liked best was new insights, wild ideas, honest argument. I first heard the concept of “steel-manning” from him (opposite of “straw man” – putting forth the strongest, best version of an argument you want to critique). He was not interested in cheap wins or rhetorical bullying – he wanted to get to the best version of every story about nature and about ourselves.

I first came into contact with Dan through his books. As a teenager, Brainstorms, Elbow Room, and The Intentional Stance were a fantastic introduction to the most interesting questions, and ways of thinking about them. My dad and I would hit the bookstores every Saturday and there was no way a Dennett book would escape us if a new one came out. We had lots of great times discussing the topics in his books. I eventually was able to ask Dan to sign a few of them for dad, as birthday presents.

Prof. Dr. Thomas Rademacher, MD, PhD — CEO & Co-Founder, Emergex — T-Cell Priming Immunotherapies

T-Cell Priming Immunotherapies To Provide Broad And Robust, Long-Term Immunity — Prof. Dr. Thomas Rademacher, MD, PhD — CEO & Co-Founder, Emergex Vaccines


Professor Dr. Thomas Rademacher, MD, PhD, is CEO and Co-Founder of Emergex (https://emergexvaccines.com/), a company that has developed a novel nanoparticle-based vaccine technology to deliver synthetic viral fragments via microneedles on a skin-adhesive patch. Emergex’s approach works on the principle of priming immune T-cells, opening the door for the development of universal vaccines against highly mutagenic viruses such as the seasonal flu and covid. T-cell priming offers a superior inoculation strategy over traditional vaccines, which rely on the body’s generation of antibodies and fail to keep up with seasonal mutations.

A serial entrepreneur, Professor Rademacher also serves as Emeritus Professor of Molecular Medicine at University College London (UCL) and is widely considered one of the founders of biotech from the early 1980s (having been involved in many of it’s core disciplines – from recombinant proteins, to monoclonal antibodies, to glycobiology).

Professor Rademacher has authored over 200 publications and 50 patents – 19 of which are in the nanomedicine field. In addition to being a world leader in nanomedicine, he is also an expert in fetal-maternal medicine, having produced 25 publications and filed 5 patents related to preeclampsia.

Professor Rademacher was co-Founder of the field of Glycobiology and subsequent Glycobiology Institute in Oxford and co-founded Oxford GlycoSciences, the first of Oxford University’s biotech spinouts, which, in 1998, was listed on the London Stock Exchange and reached a market capitalization of £1.7 billion. After moving to UCL, Professor Rademacher founded several biotech spin-out companies, including Rodaris Pharmaceuticals Ltd.

Ashley Kalinauskas — Founder & CEO, Torigen Pharmaceuticals — Providing Hope For Animals With Cancer

Is the Founder and CEO of Torigen Pharmaceuticals (https://www.torigen.com/), a company dedicated to researching and developing novel immuno-oncology products and services specifically for the veterinary market, with a focus on autologous cancer vaccines.

Torigen Pharmaceuticals is a start‑up that resulted from Ashley’s graduate thesis project at the University of Notre Dame, as she was working on her Masters in Engineering, Science and Technology Entrepreneurship in collaboration with Dr. Mark Suckow (https://www.research.uky.edu/staff/ma…). Ashley also received an undergraduate degree in Veterinary Pathology and Pathobiology from University of Connecticut.

Risk of bird flu spreading to humans is ‘enormous concern’, says WHO

“This remains I think an enormous concern,” the UN health agency’s chief scientist, Jeremy Farrar, told reporters in Geneva.

Cows and goats joined the list of species affected last month – a surprising development for experts because they were not thought susceptible to this type of influenza. US authorities reported this month that a person in Texas was recovering from bird flu after being exposed to dairy cattle, with 16 herds across six states infected apparently after exposure to wild birds.

The A(H5N1) variant has become “a global zoonotic animal pandemic”, Farrar said.

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