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Under-the-skin electrode allows for real-world epilepsy tracking

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London in partnership with the Mayo Clinic and UNEEG medical, has found that an electronic device placed under the scalp is an effective and feasible means of accurately tracking epilepsy.

In their study, published in Epilepsia, researchers demonstrated that seizures can be tracked in the , giving clinicians access to data that could have a dramatic impact on the way in which is treated in the future.

Tracking over time is challenging and relies upon a person keeping a subjective diary. It is an unreliable format, as people with epilepsy can experience seizures without realizing it, due to impairment of consciousness and memory loss, or might misinterpret several symptoms as seizures when they are not. This is particularly important for those with treatment resistant epilepsy, who have ongoing seizures despite treatment with anti-seizure medication—known to occur in around a third of people with epilepsy.

From Genome to Geroscience: How DNA Damage Shapes Systemic Decline

Persistent genomic instability compromises cellular viability while also triggers non-cell-autonomous responses that drive dysfunction across tissues, contributing to aging. Recent evidence suggests that DNA damage activates secretory programs, including the release of inflammatory cytokines, damage-associated molecular patterns, and extracellular vesicles, that reshape immune homeostasis, stem cell function, and metabolic balance. Although these responses may initially support tissue integrity and organismal survival, their chronic activation has been associated with tissue degenerative changes and systemic decline. Here, we discuss how nuclear DNA damage responses trigger the activation of cytoplasmic sensing pathways, promote secretory phenotypes, and affect organismal physiology. Targeting DNA damage-driven mechanisms may help buffer harmful systemic responses while preserving regeneration and immune surveillance, offering new ways to delay aging-related decline.

© 2025 The Author(s). BioEssays published by Wiley‐VCH GmbH.

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Scientists Discover “Master Key” Protein for Stronger Memory and Learning

Research led by Rutgers suggests there could be significant new possibilities for treating neurodegenerative diseases and brain injuries.

Researchers have uncovered how a specific protein supports the stability of connections between brain cells, which are essential for learning and memory.

According to the scientists, their findings, published in the journal Science Advances.

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